|Products||Mammals microRNA Microarray from LC Sciences|
|Item||Mammals microRNA Microarray|
|Description|| Microarrays designed for genome-wide microRNA expression profiling and built on the flexible and powerful µParaflo™ microfluidic on-chip synthesis platform. These microarrays are available as part of our comprehensive microRNA Expression Profiling Service.|
The Mammals microRNA Microarray contains all known mammal microRNAs (873 unique mature sequences). The comprehensive probe content is based on the latest version of the Sanger miRBase sequence database (Release 12.0, Sept 2008). Add up to 100 custom sequences at no extra charge.
These are not spotted arrays. The µParaflo™ microfluidic technology enables on-chip synthesis ensuring high probe quality, tight process control, and complete content flexibility. In addition, the microfluidic technology produces a uniform distribution of the sample solutions on the array and enhances binding reactions and stringency wash processes.
The Tms of our detection probes are balanced by incorporation of modified nucleotides with increased binding affinities that improve detectability and specificity in our arrays compared to those made from regular DNA probes.
Multiple QC steps are implemented at various stages of the array manufacturing process. Based on the reading from 16 sets of control probes spatially distributed across the array, signal intensities, spot uniformity, cross-array spot-to-spot uniformity, and perfect-match vs. mismatch specificities are thoroughly evaluated.
LC Sciences is a genomics and proteomics company offering innovative, customizable, and comprehensive microarray services for nucleic acid/protein profiling and functional analysis, biomarker-discovery, novel drug screening, and the custom development of diagnostic devices. We provide unique one-stop products and services for assays of DNA, RNA, protein, enzymes, antibodies, or small molecules, as well as proven microfluidic technology and novel microarray chemistry for design of your miniaturized assay devices for diagnostics and biosensing applications.
Our microarray services include the use of custom synthesized microarrays based on the µParaflo™ on-chip synthesis technology which enables the total customization of content on each individual microarray. Our customers have the flexibility to use our standard probe content or their own custom designed probe content and to use probes of their chosen lengths and number of replicates. The µParaflo™ technology also provides the flexibility of synthesizing microarrays containing probes with modifications such as, 5’-amino linker, phosphate, biotin, and various methylation or other types of modifications. Incorporation of modifications greatly increases the number of applications for these microarrays.
LC Sciences offers additional µParaflo™ technology derived products that serve customer’s needs for construction of biomolecular libraries containing up to millions of different biomolecules of defined sequences. These products significantly reduce the cost and increase the speed of highly multiplexing genome-scale experiments such as exploration of small RNAs and designer gene/DNA library synthesis.
|Info|| LC Sciences|
2575 W. Bellfort
Houston, TX 77054
Fax Number: (713) 664-8181
Web Site: http://www.lcsciences.com/miRNA_product_pages/mammals_array.html