|Products||DNA/RNA Aptamer Microarray - Comprehensive Service from LC Sciences|
|Item||DNA/RNA Aptamer Microarray - Comprehensive Service|
|Description|| LC Sciences provides unique aptamer microarray services using a novel Paraflo technology, aptamer sequence databases, and sequence design software to suit your needs for basic research and screening of aptamers as drug candidates. This comprehensive service includes assistance with sequence design, synthesis of standard or custom DNA/RNA (2-OMe) microarrays, binding assays using proteins, nucleic acids, carbohydrates, or other kinds of small molecules provided by you, single or dual color detection of the binding using a suitable method, image data processing, and signal data processing. Two-four weeks after receiving your sample(s), we send you the analyzed data, representative and original images of the array, and raw data. We offer additional services for in-depth binding data analysis and curve analysis of quantitative measurements.|
LC Sciences is a genomics and proteomics company offering innovative, customizable, and comprehensive microarray services for nucleic acid/protein profiling and functional analysis, biomarker-discovery, novel drug screening, and the custom development of diagnostic devices. We provide unique one-stop products and services for assays of DNA, RNA, protein, enzymes, antibodies, or small molecules, as well as proven microfluidic technology and novel microarray chemistry for design of your miniaturized assay devices for diagnostics and biosensing applications.
Our microarray services include the use of custom synthesized microarrays based on the Paraflo on-chip synthesis technology (1,2) which enables the total customization of content on each individual microarray. Our customers have the flexibility to use our standard probe content or their own custom designed probe content and to use probes of their chosen lengths and number of replicates. The Paraflo technology also provides the flexibility of synthesizing microarrays containing probes with modifications such as, 5-amino linker, phosphate, biotin, and various methylation or other types of modifications. Incorporation of modifications greatly increases the number of applications for these microarrays.
LC Sciences offers additional Paraflo technology derived products that serve customers needs for construction of biomolecular libraries containing up to millions of different biomolecules of defined sequences. These products significantly reduce the cost and increase the speed of highly multiplexing genome-scale experiments such as exploration of small RNAs and designer gene/DNA library synthesis.
(1) Tian, J., Gong, H., Sheng, N., Zhou, X., Gulari, E., Gao, X., and Church, G. (2004) Accurate multiplex gene synthesis from programmable DNA chips. Nature 432, 1050-1054.
(2) Zhou, X., Cai, S., Hong, A., Yu, P., Sheng, N., Srivannavit, O., Yong, Q., Muranjan, S., Rouillard, J. M., Xia, Y., Zhang, X., Xiang, Q., Ganesh, R., Zhu, Q., Makejko, A., Gulari, E., and Gao, X. (2004) Microfluidic picoarray synthesis of oligodeoxynucleotides and simultaneously assembling of multiple DNA sequences. Nucleic Acids Res. 32, 5409-5417.
|Info|| LC Sciences|
2575 W. Bellfort
Houston, TX 77054
Fax Number: (713) 664-8181
Web Site: http://www.lcsciences.com