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ApoBrdU Red DNA Fragmentation Kit from MBL International

ProductsApoBrdU Red DNA Fragmentation Kit from MBL International
Company MBL International
Item ApoBrdU Red DNA Fragmentation Kit
Price 
Description The TUNEL-based assay kit provides complete components including positive and negative control cells for convenient detection of DNA fragmentation in cultured cells and tissue sections. The incorporation of BrdU in the procedure provides greater sensitivity than biotinylated or digoxigenylated methods. Results can be analyzed by flow cytometry. The kit works well with GFP transfected cells

Internucleosomal DNA fragmentation is a hallmark of apoptosis in mammalian cells. MBLs Apo-BrdU In Situ DNA Fragmentation Assay Kit provides complete components including positive and negative control cells for conveniently detecting DNA fragmentation by fluorescence microscopy or flow cytometry. The kit utilizes Br-dUTP (bromolated deoxyuridine triphosphate nucleotides) which is more readily incorporated into DNA strand breaks than other larger ligands (e.g., fluorescein, biotin or digoxigenin). The greater incorporation gives rise to brighter signal when the Br-dUTP sites are identified by a red TRITC-labeled anti-BrdU monoclonal antibody. The assay is suitable for studying apoptosis in GFP- or Azami Green-transfected cells.
Info MBL InternationalMBL International
15 B Constitution Way
Woburn, MA 01801
Customer Service: 781-939-6964
Fax Number: 781-939-6963
Web Site: http://mblintl.com
NOTE: Price information is approximate list price and actual prices may vary.

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