|Products||Antisense oligonucleotides from Thermo Scientific|
|Description|| Phosphothioate (PTO) oligonucleotides: |
PTOs are internucleotide modifications, where one oxygen atom in the phosphate backbone is replaced by a sulphur atom. This modification stabilises the oligonucleotide against nuclease degradation. PTOs are available as
All internucleotide linkages are phosphothioates
Oligonucleotides with thio-caps
Several internucleotide linkages at the 3 and/or 5 end are synthesised as phosphothioates (PTOs) to prevent enzymatic degradation.
|Info|| Thermo Scientific|
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