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Anti-Cullin-3 (CUL-3) Ab-1 Polyclonal Antibody, Unconjugated from Lab Vision

ProductsAnti-Cullin-3 (CUL-3) Ab-1 Polyclonal Antibody, Unconjugated from Lab Vision
Company Lab Vision
Item Anti-Cullin-3 (CUL-3) Ab-1 Polyclonal Antibody, Unconjugated
Price $85.00
Description CUL-3 is a member of the family of human cullin genes (CUL-1, -2, -3, -4a, -4b, and -5), homologous to the S. cerevisiae cdc53 gene. Cullin-3 is proposed to be a part of E3 protein-ubiqutinnn ligase. It forms a tight complex with cyclin E and targets it for ubiquitination, which leads to its degradation by protesomes. Cyclin E is an activator of cdk2, which leads the cell to S phase. Cul-3-/- mice show increased accumulation of Cyclin E protein and disruption of normal cell cycle regulation in vivo. Thus Cullin-3 is important in the regulation of S phase of cell cycle.
Species Reactivity: Human and Mouse. Others-not tested.
Info Lab VisionLab Vision
47777 Warm Springs Blvd.
Fremont, CA 94539
Customer Service: 800-828-1628
Fax Number: 510-991-2826
Web Site: http://www.labvision.com
NOTE: Price information is approximate list price and actual prices may vary.

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