Navigation Links
ATTO-TAG CBQCA derivatization reagent (CBQCA; 3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde) from Molecular Probes (Invitrogen)

ProductsATTO-TAG CBQCA derivatization reagent (CBQCA; 3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde) from Molecular Probes (Invitrogen)
Company Molecular Probes (Invitrogen)
Item ATTO-TAG CBQCA derivatization reagent (CBQCA; 3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde)
Price 
Description Molecular Probes is pleased to offer the ATTO-TAG series of reagents for the ultrasensitive detection of primary amines. Developed by Novotny and collaborators at Indiana University, the ATTO-TAG reagents are similar to the important reagents o-phthaldialdehyde (OPA), naphthalene-2,3-dicarboxaldehyde (NDA) and anthracene-2,3-dicarboxaldehyde, all of which are also available in high purity form from Molecular Probes.


Principle:
ATTO-TAG CBQCA (3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde or CBQCA 1) and ATTO-TAG FQ (3-(2-furoyl) quinoline-2-carboxaldehyde 2) react specifically with primary amines to form conjugates that can be analyzed by electrophoretic or chromatographic methods. Unlike OPA and NDA, ATTO-TAG CBQCA will also react with hydrophilic peptides and amino sugars. The resulting products of CBQCA ? highly fluorescent 7-aza-1-cyano-5,6-benzisoindoles are maximally excited at 450nm or by the 442 nm spectral line of the He-Cd laser and have emission maxima at ~550 nm. The products of ATTO-TAG FQ are maximally excited at 480 nm or by the 488 nm line of the argon-ion laser and have emission maxima at ~590 nm. In capillary zone electrophoresis (CZE), the sensitivity of detection of ATTO-TAG CBQCA conjugates should be in the attomole range (10-18 moles). The high sensitivity, freedom from background and long-wavelength excitability make these potential reagents for research, diagnostic and forensic applications, including drug analysis. The ATTO-TAG reagents can, of course, be used in HPLC and other modes of chromatography with either absorbance or fluorescence detection. The principal limitation to obtaining ultrasensitive detection using chemical derivatization reagents, including the ATTO-TAG reagents, is that relatively high concentrations of the derivatizing reagent are required to obtain adequate kinetics and sufficient modification of the analyte. A recently described technique employs ATTOTAG FQ for the solid-phase derivatization of dilute solutions (10-8 M) of peptides that have been immobilized on Immobilon-CD membranes. This method permits the quantitative derivatization and analysis by capillary electrophoresis of only a few picomoles of the analyte.
Info Molecular Probes (Invitrogen)Molecular Probes (Invitrogen)
PO Box 22010
Eugene, OR 97402-0469

Call Molecular Probes (Invitrogen) to buy products (US and Canada only; other locations use numbers below)
USA Canada 1-541-359-2658
Customer Service: 1-541-465-8300
Fax Number: 1-541-344-6504
Web Site: http://probes.invitrogen.com
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. ATTO-TAG FQ Amine-Derivatization Kit from Molecular Probes (Invitrogen)
2. ATTO-TAG CBQCA Amine-Derivatization Kit from Molecular Probes (Invitrogen)
3. Mouse Anti-Ubiquitin, Multi Monoclonal Antibody, Unconjugated, Clone FK2 from Assay Designs/Stressgen Bioreagents
4. Rabbit Anti-Human ErbB-2, phospho (Tyr1248) Polyclonal Antibody, Unconjugated from Assay Designs/Stressgen Bioreagents
5. Flashlight-Trigger Solution from Assay Designs/Stressgen Bioreagents
6. Acridinium Ester Trigger Solutions from Assay Designs/Stressgen Bioreagents
7. Acridinium C2 NHS Ester from Assay Designs/Stressgen Bioreagents
8. COX Chemiluminescence Assay Kit from Assay Designs/Stressgen Bioreagents
9. Rat Osteopontin EIA Kit from Assay Designs/Stressgen Bioreagents
10. Protein G EIA Kit from Assay Designs/Stressgen Bioreagents
11. Mouse IgG3 EIA Kit from Assay Designs/Stressgen Bioreagents
Request Info...
... X-Gal ,MOLECULAR BIOLOGY GRADE ,5-Bromo-4-chloro-3-indoxyl-beta-D-galactopyranoside C ... Cl N O 6 ,M.W.= ... ,Solution: Clear (2% in DMF) ,Biological ... and M13 ,Elemental Analysis: Agrees with ...
...
... Casein Kinase 1, active MW: ... 150mM NaCl, 0.02% Brij-35, 1mM dithiothreitiol ... Activity data, refer to the Certificate ... enzyme. Purification: ammonium salt precipitation followed ...
Biology Products:
(Date:7/7/2015)... 30, 2015 Research ... addition of the "Capacitive Fingerprint Sensors Patent ... To this date, fingerprint sensing technology is the ... sensors are well developed. This patent landscape focuses ... The domain of capacitive fingerprint sensors is ...
(Date:7/2/2015)... -- Research and Markets( http://www.researchandmarkets.com/research/jvft55/next_generation ) ... Biometrics Market by Application, Technology, Function & Geography - ... The next generation biometrics market is expected ... of 17.9% between 2015 and 2020 Travel ... Safran SA ( France ), ...
(Date:6/29/2015)... Research and Markets( http://www.researchandmarkets.com/research/zj7h4f/latin_america ... America Biomedical Sensors Market - Growth, Trends & Forecasts ... Latin America Biomedical Sensors market is estimated at $0.65 ... the period 2014-2020 The near future will ... formulation of each individual. These sensors can be set ...
Breaking Biology News(10 mins):Worldwide Capacitive Fingerprint Sensors Patent Landscape Market Report 2015-2020 - Main IP Holders include Seiko Epson, AuthenTec, Sony and STMicroelectronics 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 2Next Generation Biometrics Market 2015 - Global Forecast to 2020 with Safran, NEC, 3M Cogent, Fujitsu & Suprema Dominating the $24 Billion Market 3Latin America Biomedical Sensors Market Report 2015-2020 2
... New York Researchers at the Polytechnic Institute of ... Dentistry (NYUCD) have developed a carrier in their lab ... into cells than today,s commercial delivery methodsreagent vectors. This ... separate, less effective vectors that are used to carry ...
... CAMBRIDGE, Mass. Discussions on curbing climate change tend ... scheme aimed at controlling carbon, or a tax on ... at MIT finds that a "segmental" approach involving ... regulations or incentives can play an important role ...
... - A team of scientists from Washington State University ... known viruses employs burglary-ring-like teamwork to infiltrate the human ... the nation,s top infectious disease experts served as consultants ... which is based on a global Nipah outbreak. ...
Cached Biology News:Researchers engineer a hybrid 5 times more effective in delivering genetic material into cells 2Study finds piece-by-piece approach to emissions policies can be effective 2Study finds piece-by-piece approach to emissions policies can be effective 3WSU scientists find burglary-ring-like mechanism in lethal 'Contagion' virus 2WSU scientists find burglary-ring-like mechanism in lethal 'Contagion' virus 3
(Date:7/30/2015)... globe, ISN improves the efficiency and effectiveness of contractor management systems. ISN,s online contractor ... in over 80 countries. ... ... Over 60,000 Worldwide Customers In More Than 80 Countries ... Dallas, TX , ISN has additional offices in Calgary , ...
(Date:7/30/2015)... WARRINGTON, Pa. , July 30, 2015 /PRNewswire/ ... announced that it has received the second $1.0M ... Business Innovation Research (SBIR) grant valued at up ... the company,s aerosolized KL4 surfactant as a potential ... lung injury.  Discovery Labs was awarded an initial ...
(Date:7/29/2015)... Sanofi, a global and ... quarter of 2015. CEO Olivier Brandicourt ... in different businesses. Watch video interview ... Topics covered in the interview include:  ... Performance drivers - Diabetes ...
(Date:7/29/2015)... , July 29, 2015 US-Australian drug ... ) today confirmed it is committed to progressing its ... soon as practicable and to ensure the Company delivers ... Executive Officer, Iain Ross , said the Company ... the lead pre-clinical programs, discovery programs and academic partnerships ...
Breaking Biology Technology:ISN Reaches Over 60,000 Worldwide Customers 2ISN Reaches Over 60,000 Worldwide Customers 3Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 2Discovery Labs Receives $1.0 million under an SBIR Grant in Continuing Support of the Development of Aerosolized KL4 Surfactant to Address Radiation-Induced Lung Injury 3Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 2Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 3Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 4Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 5Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 6Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 7Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 8Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 9Newly Appointed Acting CEO Outlines Immediate Plans for Novogen 10