Navigation Links
ATTO-TAG CBQCA derivatization reagent (CBQCA; 3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde) from Molecular Probes (Invitrogen)

ProductsATTO-TAG CBQCA derivatization reagent (CBQCA; 3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde) from Molecular Probes (Invitrogen)
Company Molecular Probes (Invitrogen)
Item ATTO-TAG CBQCA derivatization reagent (CBQCA; 3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde)
Price 
Description Molecular Probes is pleased to offer the ATTO-TAG series of reagents for the ultrasensitive detection of primary amines. Developed by Novotny and collaborators at Indiana University, the ATTO-TAG reagents are similar to the important reagents o-phthaldialdehyde (OPA), naphthalene-2,3-dicarboxaldehyde (NDA) and anthracene-2,3-dicarboxaldehyde, all of which are also available in high purity form from Molecular Probes.


Principle:
ATTO-TAG CBQCA (3-(4-carboxybenzoyl)quinoline-2-carboxaldehyde or CBQCA 1) and ATTO-TAG FQ (3-(2-furoyl) quinoline-2-carboxaldehyde 2) react specifically with primary amines to form conjugates that can be analyzed by electrophoretic or chromatographic methods. Unlike OPA and NDA, ATTO-TAG CBQCA will also react with hydrophilic peptides and amino sugars. The resulting products of CBQCA ? highly fluorescent 7-aza-1-cyano-5,6-benzisoindoles are maximally excited at 450nm or by the 442 nm spectral line of the He-Cd laser and have emission maxima at ~550 nm. The products of ATTO-TAG FQ are maximally excited at 480 nm or by the 488 nm line of the argon-ion laser and have emission maxima at ~590 nm. In capillary zone electrophoresis (CZE), the sensitivity of detection of ATTO-TAG CBQCA conjugates should be in the attomole range (10-18 moles). The high sensitivity, freedom from background and long-wavelength excitability make these potential reagents for research, diagnostic and forensic applications, including drug analysis. The ATTO-TAG reagents can, of course, be used in HPLC and other modes of chromatography with either absorbance or fluorescence detection. The principal limitation to obtaining ultrasensitive detection using chemical derivatization reagents, including the ATTO-TAG reagents, is that relatively high concentrations of the derivatizing reagent are required to obtain adequate kinetics and sufficient modification of the analyte. A recently described technique employs ATTOTAG FQ for the solid-phase derivatization of dilute solutions (10-8 M) of peptides that have been immobilized on Immobilon-CD membranes. This method permits the quantitative derivatization and analysis by capillary electrophoresis of only a few picomoles of the analyte.
Info Molecular Probes (Invitrogen)Molecular Probes (Invitrogen)
PO Box 22010
Eugene, OR 97402-0469

Call Molecular Probes (Invitrogen) to buy products (US and Canada only; other locations use numbers below)
USA Canada 1-541-359-2658
Customer Service: 1-541-465-8300
Fax Number: 1-541-344-6504
Web Site: http://probes.invitrogen.com
NOTE: Price information is approximate list price and actual prices may vary.

Related biology products :

1. ATTO-TAG FQ Amine-Derivatization Kit from Molecular Probes (Invitrogen)
2. ATTO-TAG CBQCA Amine-Derivatization Kit from Molecular Probes (Invitrogen)
3. Mouse Anti-Ubiquitin, Multi Monoclonal Antibody, Unconjugated, Clone FK2 from Assay Designs/Stressgen Bioreagents
4. Rabbit Anti-Human ErbB-2, phospho (Tyr1248) Polyclonal Antibody, Unconjugated from Assay Designs/Stressgen Bioreagents
5. Flashlight-Trigger Solution from Assay Designs/Stressgen Bioreagents
6. Acridinium Ester Trigger Solutions from Assay Designs/Stressgen Bioreagents
7. Acridinium C2 NHS Ester from Assay Designs/Stressgen Bioreagents
8. COX Chemiluminescence Assay Kit from Assay Designs/Stressgen Bioreagents
9. Rat Osteopontin EIA Kit from Assay Designs/Stressgen Bioreagents
10. Protein G EIA Kit from Assay Designs/Stressgen Bioreagents
11. Mouse IgG3 EIA Kit from Assay Designs/Stressgen Bioreagents
Request Info...
ZBP-89 (S-15)...
... UNOsphere ion exchange ... supports with high binding ... support is a strong ... particle size of 120 ...
... This CLS number is a new ... Cornings product number. If showing no ... old Sigma-Aldrich number (Z71,487-9) or contact ... clarifier: centre neck 100 mm, No. ...
Biology Products:
(Date:3/30/2017)... March 30, 2017  On April 6-7, 2017, Sequencing.com ... Genome hackathon at Microsoft,s headquarters in ... will focus on developing health and wellness apps that ... Hack the Genome is the first hackathon for ... world,s largest companies in the genomics, tech and health ...
(Date:3/27/2017)... N.Y. , March 27, 2017  Catholic ... Information and Management Systems Society (HIMSS) Analytics for ... EMR Adoption Model sm . In addition, CHS ... of U.S. hospitals using an electronic medical record ... for its high level of EMR usage in ...
(Date:3/22/2017)... March 21, 2017   Neurotechnology , a ... technologies, today announced the release of the ... provides improved facial recognition using up to 10 ... single computer. The new version uses deep neural-network-based ... and it utilizes a Graphing Processing Unit (GPU) ...
Breaking Biology News(10 mins):
(Date:4/21/2017)... ... April 21, 2017 , ... The AMA is happy to announce that $48,000 ... the nation. The scholarships are created through funds donated by model aviation organizations and ... set by the AMA Scholarship Committee, which is made up of model aviation pilots ...
(Date:4/21/2017)... ... April 21, 2017 , ... Frederick Innovative Technology ... of emerging technology-based businesses, recently earned a $77,518 grant from the Rural Maryland ... in 2004, FITCI is Frederick’s first incubator. A non-profit corporation, FITCI is a ...
(Date:4/20/2017)... ... April 20, 2017 , ... ... announced their strategic partnership to offer a full spectrum of digital security goods ... suite of biometric products and the ground-breaking proactive cybersecurity services and products through ...
(Date:4/20/2017)... (PRWEB) , ... April 20, 2017 , ... USDM ... for the life sciences and healthcare industries, is pleased to announce Holger Braemer ... established USDM subsidiary “USDM Europe GmbH” based in Germany. , Braemer is an ...
Breaking Biology Technology: