Navigation Links
Young Blood Revives Aging Muscles, Stanford Researchers Find

had found that satellite cells in younger muscles begin producing a protein dubbed Delta in response to muscle damage. Older muscles maintained the same pre-injury levels of Delta even after muscle damage. However, in the current study he found that satellite cells in elderly mice joined to younger partners ramped up Delta production to youthful levels after an injury.

The group confirmed their results by putting satellite cells from old and young mice in a lab dish with either old or young blood serum. Old satellite cells in old serum and young satellite cells in young serum both behaved as expected. But when old satellite cells were bathed in young serum they cranked up their production of Delta and began dividing. Likewise, young satellite cells decreased the amount of Delta they produced when in a dish with older serum and divided less frequently.

Rando said that it may be a general phenomenon that a person's inability to repair tissues with age-whether it's muscle, liver, skin or brain-is a matter of the regenerative cell's environment rather than the cells themselves.

Rando said that finding the youth-promoting factors in the blood is no small task. "It's as big a fishing expedition as you can possibly imagine," he said. With thousands of proteins, lipids, sugars and other small molecules in the blood serum, deciding where to look first would be tantamount to a roll of the dice. What's more, there's no evidence that the same blood component is responsible for reviving the different types of cells.

"Another approach is to pick factors that are good candidates and see if any of them or some combination recapitulate the effect of the younger blood," Rando said. His group is now looking for likely targets. He said that for some degenerative diseases such as Alzheimer's or muscular dystrophy, such blood-borne factors may be able to reactivate the regenerative cell's ability to repair tissue that has been damaged.

###


'"/>

Source:Stanford University Medical Center


Page: 1 2 3

Related biology news :

1. Young scientists turn to gel to ease side-effects of cancer treatment
2. Placenta Is A Rich Source Of Blood Stem Cells
3. Infants With Rare Genetic Disease Saved by Cord Blood Stem Cells
4. White Blood Cell Waste Disposal System Plays Critical Regulatory Role
5. Mystery Blood Vessel Disorder Implicated In Mini Strokes
6. Infants with Rare Genetic Disease Saved By Cord Blood Stem Cells
7. Stem Cells to Solve the Blood Shortage Problem?
8. Blood flow in brain takes a twist, affecting views of Alzheimers
9. Blood test predicts success of quitting smoking using the nicotine patch
10. Blood-compatible nanoscale materials possible using heparin
11. Blood transfusion-transmitted infections: A global perspective
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Young Blood Revives Aging Muscles Stanford Researchers Find

(Date:7/9/2014)... has uncovered how a complex protein pivotal in the ... activated. The discovery answers a key question about one ... has been the subject of tens of thousands of ... , Jiazhen Zhang, a research student in Professor Sir ... how the protein complex, called NF-κB, is activated. ...
(Date:7/9/2014)... out one gene for another in a line of ... to reality within this decade. As with any new ... fixing disease-causing genes in humans, for example--as well as ... one of those concerns to rest: using gene-editing techniques ... mutations in the cells. The new results were published ...
(Date:7/9/2014)... geographic ranges in which animals can be found, concern ... Does an increased range for a host mean new ... says a team of UC Santa Barbara scientists, including ... published in the Journal of Biogeography , Hechinger, ... opposite may happen: Hosts may actually lose their parasites ...
Breaking Biology News(10 mins):Research reveals how key controller protein is switched on 2No extra mutations in modified stem cells, study finds 2No extra mutations in modified stem cells, study finds 3Not at home on the range 2Not at home on the range 3Not at home on the range 4
... structure of feathers in bird-like dinosaurs has shed light on ... have evolved. Academics at the Universities of Bristol, ... much more primitive version of the wings we see today, ... gliding. Close examination of the earliest theropod dinosaurs suggests ...
... of The Journal of Experimental Biology are pleased ... this year,s JEB Outstanding Paper Prize. Awarded in memory of ... the junior author who made the most significant contribution to ... by the Editors from a short list of eight articles ...
... to find out about its migrations, various research centres ... and Switzerland have conducted research detailing its routes and ... it is that the wasps returning to Europe from ... which makes them more resistant to their natural European ...
Cached Biology News:New evidence of dinosaurs' role in the evolution of bird flight 2Nicole George wins 2012 Journal of Experimental Biology Outstanding Paper Prize 2Nicole George wins 2012 Journal of Experimental Biology Outstanding Paper Prize 3Nicole George wins 2012 Journal of Experimental Biology Outstanding Paper Prize 4Researchers detail the migrations of the wood wasp Sirex noctilio 2
(Date:1/15/2014)... The Pittcon Organizing Committee is pleased to announce ... , an e-Journal and producer of Food Labs ... year for the co-location of Food Labs Conference to be ... the registration fee to attend the two-day Food Lab Conference, ...
(Date:1/15/2014)... Jan. 15, 2014 ­ RedBrick Health , a ... technology, today announces that EmblemHealth , the ... company, is now providing the RedBrick Compass health assessment, ... to all of its members. EmblemHealth is among the ...
(Date:1/15/2014)... (PRWEB) January 15, 2014 The Microcompetition with ... major disease. One of these latent viruses is the Epstein ... arthritis (RA). Rheumatoid arthritis (RA) is a chronic inflammatory disease ... a study found that RA patients have high concentrations of ...
(Date:1/15/2014)... Jan. 15, 2014 TaiGen Biotechnology Company, Limited ("TaiGen") ... with R-Pharm, a leading Russian pharmaceutical company, to develop ... Russian Federation , Turkey ... (CIS). Nemonoxacin is a novel antibiotic for the treatment of ...
Breaking Biology Technology:Pittcon Announces Second Year Partnership With Food Safety Tech 2Pittcon Announces Second Year Partnership With Food Safety Tech 3EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 2EmblemHealth Selects RedBrick Health to Power its Next-Generation Health Engagement and Behavior Change System 3Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 2Study: Rheumatoid Arthritis (RA) Patients Have EBV; The CBCD Says this is Consistent with Microcompetition 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 2TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 3TaiGen Biotechnology Signed Exclusive License Agreement with R-Pharm for Nemonoxacin (Taigexyn(R)) 4
... Southwestern to Leverage WaferGen,s SmartChip Platform to ... SCOTTSDALE, Ariz., March 24 WaferGen Biosystems, ... developer of state-of-the-art genetic analysis systems, and ... IRBS), a development-stage biotechnology company focused on ...
... - Stemgent to provide CellDesign,s proprietary adipocyte differentiation ... 24 Stemgent has signed a co-exclusive license ... MaxiKit, which enable researchers to grow and study ... strengthens Stemgent,s position as a provider of leading ...
... HHOMonster.com launches it,s website full of products that help burn gasoline ... ... 2009 -- HHOMonster.com (HHOMonster LLC), a company located near Orlando, Florida, ... Injection Systems (Hydrogen Generators). These units use the electricity generated ...
Cached Biology Technology:WaferGen Biosystems, ImmuneRegen BioSciences and University of Texas Southwestern Medical Center to Collaborate on Novel Wound Healing Research 2WaferGen Biosystems, ImmuneRegen BioSciences and University of Texas Southwestern Medical Center to Collaborate on Novel Wound Healing Research 3WaferGen Biosystems, ImmuneRegen BioSciences and University of Texas Southwestern Medical Center to Collaborate on Novel Wound Healing Research 4WaferGen Biosystems, ImmuneRegen BioSciences and University of Texas Southwestern Medical Center to Collaborate on Novel Wound Healing Research 5WaferGen Biosystems, ImmuneRegen BioSciences and University of Texas Southwestern Medical Center to Collaborate on Novel Wound Healing Research 6WaferGen Biosystems, ImmuneRegen BioSciences and University of Texas Southwestern Medical Center to Collaborate on Novel Wound Healing Research 7Stemgent, CellDesign Sign Co-Exclusive Marketing Agreement on Stem Cell-Based Adipocyte Research Products 2New Website Offers Fuel Saving Products Such as Hydrogen Injection Systems and Hydrogen Generators 2
GOAT ANTI HUMAN PSA (ISOFORM 1)...
Human Carnosine Dipeptidase 1 Affinity Purified PAb...
... and P-selectin glycoprotein ligand-1 (PSGL-1) mediate the ... surface of endothelial cells at sites of ... of PSGL-1 in mediating the interaction between ... completely blocks recognition of PSGL-1 by either ...
Mouse Anti-Human MCAF-(MCP-1)...
Biology Products: