Navigation Links
York mathematician probes geometric route to combat viruses

A mathematician at the University of York has been awarded a Research Leadership Award of more than £700,000 by the Leverhulme Trust to study the geometry of viruses.

Dr Reidun Twarock, an Anniversary Reader in the Departments of Biology and Mathematics, will study the structure and assembly of viruses, which will help to develop new anti-viral strategies.

Viruses have highly symmetrical external shells formed from proteins that encapsulate the viral genome. Dr Twarock has developed a method for encoding the structures of these protein shells that pinpoint the locations of the proteins and the bonds between them. With collaborators Professor Cristian Micheletti, from the International School for Advanced Studies (SISSA) in Trieste, Italy, and Professor Anne Taormina, from the University of Durham, she has used these results to model the assembly of viruses.

Subsequent work with collaborators Professor Peter Stockley, Dr Neil Ranson and their groups at the Astbury Centre for Structural Molecular Biology at the University of Leeds suggests that not only the geometry of the viral capsids themselves but also the full three-dimensional structures of the particles are constrained. The implications of this discovery on virus assembly are currently being investigated.

Dr Twarock said: “I would like to use the Leverhulme Trust Award to build up a group of mathematicians, computational biologists and biophysicists to address a portfolio of projects arising from these results.?

This grant will enable Dr Twarock to expand her group and fund three postdoctoral positions and four PhD students. The group will collaborate closely with the Astbury Centre in Leeds, and they will jointly organise a workshop on Mathematical Virology at the International Centre for Mathematical Sciences in August 2007.

Dr Twarock’s group will be part of the York Centre of Complex Systems Analysis (YCCSA), including biologists, mathematicians and computer scientists, which is based in the Department of Biology at York.


'"/>

Source:University of York


Related biology news :

1. Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
2. Products containing specific probes for detecting alternative splice forms protected
3. Smart nanoprobes light up disease
4. UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice
5. BRCA1 causes ovarian cancer through indirect, biochemical route
6. UIC researchers show protein routes messages in nerve cells
7. Researchers discover new route to hemoglobin synthesis
8. Evolution reveals an independent route for diversity in animal form
9. Molecular machine may lead to new drugs to combat human diseases
10. A bacterial genome reveals new targets to combat infectious disease
11. Light therapy may combat fungal infections, new evidence suggests
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/26/2016)... 2016 Research and Markets has ... Market 2016-2020"  report to their offering.  , ,     ... The analysts forecast the global multimodal biometrics market ... the period 2016-2020.  Multimodal biometrics is ... as the healthcare, BFSI, transportation, automotive, and government ...
(Date:4/13/2016)... -- IMPOWER physicians supporting Medicaid patients in Central ... in telehealth thanks to a new partnership with higi. ... patients can routinely track key health measurements, such as ... when they opt in, share them with IMPOWER clinicians ... retail location at no cost. By leveraging this data, ...
(Date:3/22/2016)... , March 22, 2016 ... report "Electronic Sensors Market for Consumer Industry by Type ... Others), Application (Communication & IT, Entertainment, Home ... Global Forecast to 2022", published by MarketsandMarkets, ... expected to reach USD 26.76 Billion by ...
Breaking Biology News(10 mins):
(Date:4/28/2016)... ... April 28, 2016 , ... As part of an ... experts, and expanding its LATAM network and logistics capabilities. Enhancements have been ... their clinical trial projects. , The expansion will provide unmatched clinical trial logistics ...
(Date:4/27/2016)... ... April 27, 2016 , ... Most consumers engage with ... recognition for secure access, voice recognition for hands-free communication, and facial recognition to ... with biometrics technology today. But if they asked Joey Pritikin, Vice President ...
(Date:4/27/2016)... ... April 27, 2016 , ... PathSensors, Inc., a leading environmental ... Lamka will assist PathSensors in expanding the use of the company’s CANARY® technology ... test platform for the detection of harmful pathogens, including a number of bacteria, ...
(Date:4/27/2016)... 27, 2016 ReportsnReports.com adds ... specific focus on US, EU, China ... to the healthcare business intelligence collection of its ... Complete report on the Flow Cytometry market spread ... with 282 tables and figures is now available ...
Breaking Biology Technology: