Navigation Links
York mathematician probes geometric route to combat viruses

A mathematician at the University of York has been awarded a Research Leadership Award of more than £700,000 by the Leverhulme Trust to study the geometry of viruses.

Dr Reidun Twarock, an Anniversary Reader in the Departments of Biology and Mathematics, will study the structure and assembly of viruses, which will help to develop new anti-viral strategies.

Viruses have highly symmetrical external shells formed from proteins that encapsulate the viral genome. Dr Twarock has developed a method for encoding the structures of these protein shells that pinpoint the locations of the proteins and the bonds between them. With collaborators Professor Cristian Micheletti, from the International School for Advanced Studies (SISSA) in Trieste, Italy, and Professor Anne Taormina, from the University of Durham, she has used these results to model the assembly of viruses.

Subsequent work with collaborators Professor Peter Stockley, Dr Neil Ranson and their groups at the Astbury Centre for Structural Molecular Biology at the University of Leeds suggests that not only the geometry of the viral capsids themselves but also the full three-dimensional structures of the particles are constrained. The implications of this discovery on virus assembly are currently being investigated.

Dr Twarock said: “I would like to use the Leverhulme Trust Award to build up a group of mathematicians, computational biologists and biophysicists to address a portfolio of projects arising from these results.?

This grant will enable Dr Twarock to expand her group and fund three postdoctoral positions and four PhD students. The group will collaborate closely with the Astbury Centre in Leeds, and they will jointly organise a workshop on Mathematical Virology at the International Centre for Mathematical Sciences in August 2007.

Dr Twarock’s group will be part of the York Centre of Complex Systems Analysis (YCCSA), including biologists, mathematicians and
'"/>

Source:University of York


Page: 1 2

Related biology news :

1. Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
2. Products containing specific probes for detecting alternative splice forms protected
3. Smart nanoprobes light up disease
4. UC Davis researchers use heated nanoprobes to destroy breast cancer cells in mice
5. BRCA1 causes ovarian cancer through indirect, biochemical route
6. UIC researchers show protein routes messages in nerve cells
7. Researchers discover new route to hemoglobin synthesis
8. Evolution reveals an independent route for diversity in animal form
9. Molecular machine may lead to new drugs to combat human diseases
10. A bacterial genome reveals new targets to combat infectious disease
11. Light therapy may combat fungal infections, new evidence suggests
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: York mathematician probes geometric route combat viruses

(Date:5/28/2015)... 28, 2015 Industry analyst firm n-tech ... report titled "Markets for Self-Healing Materials: 2015-2022." According to ... and vascular systems, biomaterials, relevant shape memory materials ... $2.7 billion by 2020. The report ... of smart materials. Other recent n-tech reports have included ...
(Date:5/22/2015)... According to a new market ... Thermal, Emotion, Forensic), by Software (Middleware, Databases), by Hardware (Cameras, ... and Home) - Global Forecast to 2020", published by ... in 2015 to $6.19 Billion by 2020, at a ... data Tables and   43 Figures spread through 140 ...
(Date:5/19/2015)... Fingerprint Cards (FPC) has received an ... and FPC1035 from one if its module partners. Deliveries are ... 2015 and the sensors will be used by smartphone manufacturers ... 2015 hereby amount to 740 MSEK to date. In addition ... and a number of smaller orders not separately communicated amounting ...
Breaking Biology News(10 mins):The Market for Self-Healing Materials to Reach $2.7 Billion by 2020 Says New n-tech Research Study 2The Market for Self-Healing Materials to Reach $2.7 Billion by 2020 Says New n-tech Research Study 3Facial Recognition Market Worth $6.19 Billion by 2020 2Facial Recognition Market Worth $6.19 Billion by 2020 3Fingerprint Cards Receives Touch Fingerprint Sensor Order of SEK 230 Million and Raises Revenue Guidance for 2015 2
... GAINESVILLE, Fla. New University of Florida research puts to ... the last glacial period. It turns out it ended up ... The findings have implications for modern-day global warming, said ... of the paper, which is published in this week,s journal ...
... team of researchers based at the Institute of Vertebrate ... professor at Washington University in St. Louis, has discovered ... anthropologists perceptions of the emergence of modern humans in ... published Oct. 25 in the online early edition of ...
... HOUSTON, Oct. 25, 2010 Some unexpected effects ... and reverse blindness have been uncovered by a University ... Donald A. Fox, a professor of vision sciences ... findings in a paper titled "Low-Level Gestational Lead Exposure ...
Cached Biology News:UF research gives clues about carbon dioxide patterns at end of Ice Age 2UF research gives clues about carbon dioxide patterns at end of Ice Age 3Unexpected findings of lead exposure may lead to treating blindness 2Unexpected findings of lead exposure may lead to treating blindness 3
(Date:5/29/2015)... LONDON , May 29, 2015 ... forward as p ersonalized   treatments enter ... Despite generic erosion facing several of ... xinafoate), Symbicort (budesonide/formoterol fumarate) and Xolair (omalizumab), the global ... growth by the end of the decade.   ...
(Date:5/29/2015)... 29, 2015 Delcath Systems, Inc. (NASDAQ: ... device company focused on oncology with an emphasis ... cancers, announces that results of a large, European ... patients with hepatic metastases with the Delcath Hepatic ... an on-line abstract at the American Society of ...
(Date:5/29/2015)... May 29, 2015  Caris Life Sciences® today ... in which researchers utilized Caris Molecular Intelligence®, the ... potential therapeutic targets in patients with colorectal and ... programmed cell death protein 1 (PD-1) and its ... at the 2015 American Society of Clinical Oncology ...
(Date:5/29/2015)... DUBLIN , May 28, 2015 ... the addition of Jain PharmaBiotech,s new report ... their offering. This report deals with ... classical use mainly to describe the chromosome structure ... age of molecular biology, it is also referred ...
Breaking Biology Technology:Personalized Treatment for Severe Asthma to Drive Market Growth Despite Patent Expirations 2Personalized Treatment for Severe Asthma to Drive Market Growth Despite Patent Expirations 3Positive Data With Delcath's CHEMOSAT Highlighted At ASCO 2015 2Positive Data With Delcath's CHEMOSAT Highlighted At ASCO 2015 3Positive Data With Delcath's CHEMOSAT Highlighted At ASCO 2015 4Positive Data With Delcath's CHEMOSAT Highlighted At ASCO 2015 5Multi-Platform Molecular Profiling from Caris Life Sciences Identifies Clinically Actionable Targets for Novel Immunotherapy Drugs 2Multi-Platform Molecular Profiling from Caris Life Sciences Identifies Clinically Actionable Targets for Novel Immunotherapy Drugs 3Multi-Platform Molecular Profiling from Caris Life Sciences Identifies Clinically Actionable Targets for Novel Immunotherapy Drugs 4Global Cytogenetics Market Report 2015-2024 - Technologies, Markets and Companies 2Global Cytogenetics Market Report 2015-2024 - Technologies, Markets and Companies 3
... China, Aug. 4 /Xinhua-PRNewswire-FirstCall/ --,Shengtai Pharmaceutical, Inc. ... Company"), a leading manufacturer and distributor,of high-quality, ... that it has retained Grayling Global to ... to shareholders, the investment,community and financial media., ...
... CryoLife, Inc. (NYSE: CRY ), a,biomaterials, medical device ... has been promoted to vice president of U.S. sales,and ... to vice,president of international sales and marketing. Both men ... worldwide sales and marketing.,Additionally, the company has announced the ...
... Radiometer today announced it,has received 510(k) clearance from ... FLEX CO-OX, a portable blood gas analyzer that ... expects commercial release,of the instrument to soon follow., ... The ABL80 FLEX CO-OX accurately measures pH, blood ...
Cached Biology Technology:Shengtai Pharmaceutical Retains Grayling Global As Investor Relations Counsel 2Shengtai Pharmaceutical Retains Grayling Global As Investor Relations Counsel 3CryoLife Announces Management Promotions 2CryoLife Announces Management Promotions 3New CO-oximetry Module for the ABL80 FLEX Blood Gas Analyzer 2
... paraffin tissue array is designed for ... interest in extensive panels of different ... heart, kidney, liver, lung, muscle, spleen ... positively charged glass slide. Each ...
EPH electrode, anode, 1. Category: Electrophoresis Systems & Standards & Reagents, IEF & SDS-PAGE & 2-D Electrophoresis, Multiphor II Kits & Components and Accessories....
LIVE/DEAD® Sperm Viability Kit *200-1000 assays*...
in vitro Translation, Accessory Products...
Biology Products: