Navigation Links
Yale participates in global human genome initiative

Yale is a founding member of the Genome-Wide RNAi Global Initiative, an alliance of top international biomedical research centers formed to speed scientific and medical discoveries that target genes of the entire human genome. The initiative is sponsored by Dharmacon, Inc., manufacturer of the first complete human genome siRNA library, or compilation of short, interfering ribonucleic acid sequences. The library is designed to determine when individual genes are functioning. It uses a format that is accessible to researchers for detailed analysis of individual genes, gene families and metabolic pathways.

The siRNA sequences have blueprints in DNA and are transcribed, but not translated into proteins. Researchers have recently found that several siRNAs regulate critical gene functions in normal development and in development of cancer.

"Participation in this consortium gives us a cutting-edge technology to systematically screen the human genome using cell-based models of human diseases," said Kevin P. White, associate professor of genetics, ecology and evolutionary biology and the lead investigator for Yale.

The library will be available to the Yale University research community and will be used to screen for human gene functions. "Coupling Yale's expertise in the molecular basis of human disease with access to this siRNA library has a tremendous potential for discoveries that will lead to better diagnostic and therapeutic solutions for a wide variety of diseases, including most forms of cancer," said White.

Founding members of the Global Initiative have a broad spectrum of biomedical research interests that will provide a forum for sharing research protocols, establishing experimental standards and developing ways to exchange and compare data. The continu ed interaction is expected to help optimize rapid, genome-wide screening and accelerate drug discovery.

The other Global Initiative founding member institutions are the Campbell Family Institute for Breast Cancer Research at Princess Margaret Hospital and the Samuel Lunenfeld Research Institute at Mount Sinai Hospital in collaboration with the University of Toronto; the Cancer Research UK (CRUK)-funded scientists at the LondonResearch Institute and the Institute of Cancer Research; the German Cancer Research Center (DKFZ); the University of Nebraska Medical School; the Netherlands Cancer Institute; the Scottish Centre for Genomic Technology and Informatics based at the University of Edinburgh Medical School and University of Texas Southwestern Medical Center.

The membership of the Global Initiative is expected to expand further as additional not-for-profit research institutions from North America, Europe and Asia join in the coming months. Its first meeting will take place in Boston on October 17-18, 2005.


'"/>

Source:Yale University


Related biology news :

1. Scientists collaborate to assess health of global environment
2. Nonlinear Dynamics announces more details of its global partnership with PerkinElmer
3. DuPonts first biologically derived polymer receives global recognition
4. Virus-host interactions at sea effect global photosynthesis
5. Hopkins AIDS experts issue warning about global efforts to provide drug therapies
6. Scientists discover global pattern of big fish diversity in open oceans
7. AIDS expert says global strategy needed to combat feminization of HIV/AIDS
8. Marine bacterium suspected to play role in global carbon and nitrogen cycles
9. Errors in the measurement of global warming corrected
10. Clean skies=faster global warming?
11. Storing carbon to combat global warming may cause other environmental problems, study suggests
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:3/28/2017)... , March 28, 2017 The ... Hardware (Camera, Monitors, Servers, Storage Devices), Software (Video Analytics, ... Region - Global Forecast to 2022", published by MarketsandMarkets, ... 2016 and is projected to reach USD 75.64 Billion ... and 2022. The base year considered for the study ...
(Date:3/24/2017)... 24, 2017 The Controller General of Immigration from ... Abdulla Algeen have received the prestigious international IAIR Award for the ... Continue Reading ... ... Controller Abdulla Algeen (small picture on the right) have received the IAIR ...
(Date:3/23/2017)... The report "Gesture Recognition and Touchless Sensing Market by Technology (Touch-based ... to 2022", published by MarketsandMarkets, the market is expected to be worth USD ... 2022. Continue Reading ... ... ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... and LAGUNA HILLS, Calif. , Oct. ... Cancer Research, London (ICR) and University ... SKY92, SkylineDx,s prognostic tool to risk-stratify patients with multiple myeloma ... MUK nine . The University of Leeds ... partly funded by Myeloma UK, and ICR will perform the ...
(Date:10/10/2017)... ... 2017 , ... San Diego-based team building and cooking events company, Lajollacooks4u, has ... The bold new look is part of a transformation to increase awareness, appeal to ... period. , It will also expand its service offering from its signature gourmet cooking ...
(Date:10/10/2017)... 10, 2017 International research firm Parks Associates announced ... at the TMA 2017 Annual Meeting , October 11 in ... residential home security market and how smart safety and security products impact ... Parks Associates: Smart Home ... "The residential security market has ...
(Date:10/9/2017)... DIEGO , Oct. 9, 2017  BioTech ... biological mechanism by which its ProCell stem cell ... critical limb ischemia.  The Company, demonstrated that treatment ... amount of limbs saved as compared to standard ... the molecule HGF resulted in reduction of therapeutic ...
Breaking Biology Technology: