Navigation Links
Xie Lab demonstrates the role of microRNA pathway

Ting Xie, Ph.D., Associate Investigator, and Zhigang Jin, Ph.D., Postdoctoral Research Associate in the Xie Lab, have published results showing that the microRNA pathway is essential for controlling self-renewal of germline stem cells and somatic stem cells in the Drosophila ovary.

The paper, "Dcr-1 Maintains Drosophila Ovarian Stem Cells," was published on the Web site of Current Biology today.

MicroRNAs are single-stranded small RNA molecules believed to regulate the expression of other genes. The Xie Lab's findings show that the microRNA pathway is essential for controlling self-renewal of two types of stem cells in the Drosophila ovary.

"The findings were interesting to us because they demonstrated that the microRNA pathway is essential for controlling self-renewal or maintenance of two types of stem cells —germline stem cells and somatic stem cells," said Dr. Jin. "In the future, the small RNAs responsible for stem cell regulation could potentially be used to control stem cell functions in vivo and stem cell expansion in vitro."

"We are in the process of identifying the microRNAs that are important for stem cell self-renewal," said Dr. Xie. "Understanding the mechanisms controlling stem cell self-renewal will be crucial to our developing the ability to expand stem cell populations for performing tissue repair."


'"/>

Source:Stowers Institute for Medical Research


Page: 1

Related biology news :

1. MRSA study demonstrates need for frequent hand washing and environmental disinfection in health care settings
2. Sangamo BioSciences demonstrates its ZFP treatment protects cells from HIV infection
3. New research demonstrates bone-marrow derived stem cells can reverse genetic kidney disease
4. NYU, Rockefeller researchers find complexity of regulation by microRNA genes
5. Molecular steps involved in the creation of gene-silencing microRNAs identified
6. Scientists find microRNAs regulate plant development
7. Role of microRNA identified in thyroid cancer
8. Twin molecular scissors link creation of microRNAs with gene-silencing
9. Single microRNA causes cancer in transgenic mouse
10. Activation of microRNA inhibits cancer gene in human cancer cells
11. Pair of microRNA molecules controls major oncogene in most common leukemia
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:4/13/2017)... India , April 13, 2017 According to ... Proofing, Identity Authentication, Identity Analytics, Identity Administration, and Authorization), Service, Authentication Type, ... MarketsandMarkets™, the IAM Market is expected to grow from USD 14.30 Billion ... Growth Rate (CAGR) of 17.3%. ... MarketsandMarkets ...
(Date:4/11/2017)... Research and Markets has announced the addition ... their offering. ... tracking market to grow at a CAGR of 30.37% during the ... 2017-2021, has been prepared based on an in-depth market analysis with ... its growth prospects over the coming years. The report also includes ...
(Date:4/11/2017)... MELBOURNE, Florida , April 11, 2017 ... "Company"), a security technology company, announces the appointment of independent ... John Bendheim to its Board of Directors, furthering the ... ... behalf of NXT-ID, we look forward to their guidance and ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... Philadelphia, PA (PRWEB) , ... October 10, 2017 ... ... University City Science Center’s FirstHand program has won a US2020 STEM Mentoring Award. ... accept the award for Excellence in Volunteer Experience from US2020. , US2020’s mission ...
(Date:10/10/2017)... ... October 10, 2017 , ... ... optimization firm for the life sciences and healthcare industries, announces a presentation by ... Francisco. , The presentation, “Automating GxP Validation for Agile Cloud Platforms,” will present ...
(Date:10/9/2017)... ... 09, 2017 , ... At its national board meeting in North Carolina, ... University’s Departments of Physics and Astronomy, has been selected for membership in ARCS ... for the 2015 Breakthrough Prize in Fundamental physics for the discovery of the accelerating ...
(Date:10/7/2017)... Seattle, WA (PRWEB) , ... ... ... the industry leader in Hi-C-based genomic technologies, launched its ProxiMeta™ Hi-C metagenome ... the ProxiMeta Hi-C kit and accompanying cloud-based bioinformatics software to perform Hi-C ...
Breaking Biology Technology: