Navigation Links
World-first Living Donor Islet Cell Transplant A Success; Procedure Offers Promise For Diabetics

A University of Alberta and Capital Health surgeon, well known for his pioneering work in developing the Edmonton Protocol treatment for diabetes, has taken another important step in the fight against diabetes.

On January 19, at Kyoto University Hospital, Dr. Koichi Tanaka and Dr. James Shapiro, along with a team of Japanese surgeons, removed part of a 56-year-old woman's pancreas. Dr. Shinichi Masumoto then isolated the living islets in the Kyoto Centre for Cell and Molecular Therapy. Under Dr. Shapiro's supervision, the team then transplanted the insulin-producing cells into the woman's 27-year-old diabetic daughter.

The transplanted islets began producing insulin within minutes, explains Dr. Shapiro. "The reason I'm so excited about this is because normally the Edmonton Protocol is done with islets from brain-dead organ donors. Those islets are often severely injured from cold storage, transport time and the pancreas is severely damaged by toxins which circulate in the blood stream after brain death."

"Our expectation is that these islets from near-perfect organs will work better, although it's too early to tell," he says.

The recipients use the same drugs to prevent organ rejection as are used in the Edmonton Protocol.

Dr. Shapiro was invited to participate in the operation in Kyoto, Japan, where he originally did living donor liver transplant training with Dr. Tanaka. Dr. Masumoto was previously based in Seattle and had been involved in Dr. Shapiro's international trial of the Edmonton Protocol before returning to Japan. Dr. Shapiro first suggested the idea of starting a living donor islet transplant program in Kyoto while lecturing there three years ago. Cadaveric organ donors are scarce in Japan, and living donation has very established roots in liver and kidney transplantation there.

"Living donor islet transplants could allow many more desperate patients with type 1 diabetes to get successful islet transplants,
'"/>

Source:University of Alberta


Page: 1 2

Related biology news :

1. World-first technology enables study of ancient bacteria
2. Living with salt
3. Living anti-HIV gel shows early promise
4. Living taste cells produced outside the body
5. Living laboratory found on shoreline statues
6. Study: Living coral reefs provide better protection from tsunami waves
7. Living view in animals shows how cells decide to make proteins
8. Living with water scarcity -- world must act now
9. First North American Encapsulated Islet Transplant without Long-term Immune Suppression into a Patient with Type 1 Diabetes
10. Single-donor Islet Transplantation Procedure Shows Promise For Patients With Type 1 Diabetes
11. Transplantation Of Monkey Embryonic Stem Cells Reverses Parkinson Disease In Primates
Post Your Comments:
(Date:9/22/2014)... September 23, 2014 A new American Cancer Society ... Assistance Program (SNAP), previously known as the food ... with income eligible non-participants. The authors say the ... at enhancing the dietary quality of SNAP participants. ... individuals and households with the resources to obtain ...
(Date:9/22/2014)... researchers are studying a potential new treatment that reverses ... which scars develop in the lungs and severely hamper ... which is delivered to lung tissue intravenously. In mouse ... fibrosis after several days. , The findings were ... Medicine . , "The mimic, when injected into the ...
(Date:9/22/2014)... genetic sequencing technologies continue to evolve rapidly, becoming part ... establish appropriate policies and regulatory frameworks to address potential ... policy issue of the Journal of Law, Medicine ... experts with the Center for Medical Ethics and Health ... the tools to jumpstart this process. , Experts ...
Breaking Biology News(10 mins):Federal food program puts food on the table, but dietary quality could be improved 2Reversing the effects of pulmonary fibrosis 2Experts provide much-needed policy analysis for clinical integration of next generation sequencing 2Experts provide much-needed policy analysis for clinical integration of next generation sequencing 3
... Director,s T-R01 Award , Speedier Lab Testing With Results ... associate professor of pharmacology at Weill Cornell Medical College, ... NIH Director,s Transformative R01 award from the National Institutes ... innovative protein recognition technologies that may some day speed ...
... Fisher, associate professor in the Fischell Department of Bioengineering, ... Research and Technology Review Day with a tissue engineering ... tissue for implantation. Fisher,s technology was one of ... faculty members and graduate students at the Professor Venture ...
... Researchers have shown how an experimental drug might restore ... by preventing short circuits caused when tiny "potassium channels" ... also might be developed as a treatment for multiple ... a common type of spinal cord trauma, called "compression" ...
Cached Biology News:Weill Cornell science briefs: November 2009 2Weill Cornell science briefs: November 2009 3Weill Cornell science briefs: November 2009 4Weill Cornell science briefs: November 2009 5Bioreactor for bone tissue engineering wins professor venture fair 2Bioreactor for bone tissue engineering wins professor venture fair 3Drug studied as possible treatment for spinal injuries 2Drug studied as possible treatment for spinal injuries 3
(Date:9/23/2014)... For the fifth time since 2006, ExakTime has been ... fastest-growing companies. , “We’re so proud that ExakTime’s rapid and ... ExakTime CEO Tony Pappas said. , ExakTime earned its ranking ... rate of 61 percent from 2010 to 2013 and by ... percent. , Pappas cited strong performance in the construction market ...
(Date:9/23/2014)... 23, 2014 News Facts ... devoted to genome-based research for human health and ... is taking a bite out of oral cancer with its ... India with the help of state-of-the-art ... Networks (DDN). , To fuel its cutting-edge cancer research, ...
(Date:9/23/2014)... September 23, 2014 Equashield ... Transfer     Devices  (CSTD) for hazardous ... MedFront Medical Technology Corporation.  Equashield,s leading CSTD has ... Taiwan , China ... continues to expand globally, and throughout the ...
(Date:9/23/2014)... Plymouth, MN (PRWEB) September 23, 2014 ... named NimbeLink, a developer of cellular modems ... a finalist in the Startup category for the ... will be held at the Minneapolis Convention Center ... Minnesota companies and individuals who have shown superior ...
Breaking Biology Technology:ExakTime Makes Inc. 5000 List for the Fifth Time 2National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 2National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 3National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 4National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 5Equashield Enters Taiwan Following Expansion to Australia, Japan, China 2NimbeLink Named Finalist for 15th Annual Tekne Awards 2NimbeLink Named Finalist for 15th Annual Tekne Awards 3
... Simbionix,the world,s leading developer of medical simulation systems, ... a global collaboration,agreement. Simbionix will exclusively distribute, market, ... virtual reality hysteroscopy simulator. , ... simulators for minimal,invasive surgery. "This new agreement further ...
... Put in Place to Serve Future Requirements of Stem ... SIAL ) today announced the launch of an ... to its extensive portfolio of industry-leading products developed specifically ... over 1,100 unique and highly-focused products that are expected ...
... All amounts are in U.S. dollarsQUEBEC CITY, March 11 /PRNewswire-FirstCall/ - ... Company"), a global biopharmaceutical company focused on endocrinology and oncology, today ... full year ended December 31, 2008., 2008 Highlights, ... First patients treated with AEZS-108 for a Phase 2 trial in ...
Cached Biology Technology:Simbionix Increases Product Offerings for OB/GYN Physicians 2Sigma-Aldrich Streamlines Access to Advanced Stem Cell Research Portfolio and Opens Stem Cell Biology Community Through New Web Portal 2Sigma-Aldrich Streamlines Access to Advanced Stem Cell Research Portfolio and Opens Stem Cell Biology Community Through New Web Portal 3AEterna Zentaris Reports Fourth Quarter and Full-Year 2008 Financial and Operating Results 2AEterna Zentaris Reports Fourth Quarter and Full-Year 2008 Financial and Operating Results 3AEterna Zentaris Reports Fourth Quarter and Full-Year 2008 Financial and Operating Results 4AEterna Zentaris Reports Fourth Quarter and Full-Year 2008 Financial and Operating Results 5AEterna Zentaris Reports Fourth Quarter and Full-Year 2008 Financial and Operating Results 6AEterna Zentaris Reports Fourth Quarter and Full-Year 2008 Financial and Operating Results 7AEterna Zentaris Reports Fourth Quarter and Full-Year 2008 Financial and Operating Results 8AEterna Zentaris Reports Fourth Quarter and Full-Year 2008 Financial and Operating Results 9AEterna Zentaris Reports Fourth Quarter and Full-Year 2008 Financial and Operating Results 10
... Double staining is a technique used to ... tissue.(1-6) PicTure™-Double Staining Kit is a Zymed ... two antigens simultaneously in the same human ... The antigens can be identified using two ...
... Identical to the D-2000, but comes with ... switch) The D-2000 Deuterium Light ... nm. In addition, deep-UV versions of the light ... 190-400 nm. This powerful and stable lamp provides ...
... assay kit designed to detect poly(ADP-ribose) polymerase ... an enzyme implicated in DNA damage and ... by caspase-3. Cleavage of PARP from the ... a hallmark of apoptosis. Each kit is ...
... handy dispensers save space and ... hats, and other garb. They ... bins for small parts used ... Clear acrylic. Open-slot design for ...
Biology Products: