Navigation Links
Wisconsin researchers identify sleep gene

hours each night and lose most of their ability to respond to stimuli, the researchers found. When deprived of sleep, humans and their winged counterparts rebound on the following night by sleeping longer and more deeply. Flies also sleep more in their youth than later in life, when their sleep is fragmented, as with humans.

In other studies, the scientists also observed that caffeine has the same stimulating effects on human and fly sleep, and that similar genes are expressed in both species when they are awake and asleep. Tononi's team also conducted EEGs on the flies and found evidence of the same electrophysiological changes occurring during sleep and wakefulness as in humans.

"The electrical changes in humans look different that they do in flies because our brains are organized differently," Cirelli says. "But the EEGs showed electrophysiological changes signifying that the flies were asleep and awake."

In mammals the changes produce hallmark waves, or oscillations of groups of neurons, easily detected by EEG. The waves are slower during deep sleep and faster during waking times. One way of getting from the faster to the slower state is by opening ion channels, allowing potassium to flow through them.

"Our hypothesis is that if you don't have potassium channels, you won't get slow waves," Cirelli says. "The cell membrane will remain activated, preventing long periods of deep, non-REM sleep."

The researchers say that the fly research translates to humans even more than they thought it would. "Humans have the same kind of genes and potassium channels. And we know that slow waves must be generated by changes in the excitability of neuron cell membranes," Cirelli says.

"Potassium changes may have a huge affect on sleep in humans."

Sleep is a highly complex activity and probably involves many genes, some of which are more influential than others, says Cirelli. "We believe this gene is very powerful because it a
'"/>

Source:University of Wisconsin-Madison


Page: 1 2 3 4

Related biology news :

1. Wisconsin scientists grow critical nerve cells
2. Wisconsin scientists discover a master key to microbes pathogenic lifestyles
3. Wisconsin scientists find a way to make human collagen in the lab
4. Wisconsin scientists grow two new stem cell lines in animal cell-free culture
5. NYU researchers simulate molecular biological clock
6. Vital step in cellular migration described by UCSD medical researchers
7. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
8. UCSD researchers maintain stem cells without contaminated animal feeder layers
9. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
10. New protein discovered by Hebrew University researchers
11. First real-time view of developing neurons reveals surprises, say Stanford researchers
Post Your Comments:
(Date:12/15/2009)... signed an agreement with the British Society for Research ... the journal Biogerontology for an initial period ... member of the Biogerontology editorial board and ... Springer will sponsor the society and provide society members ... www.springerlink.com . , Biogerontology offers a ...
(Date:12/15/2009)... GenWay Biotech, Inc. GenWay Clinical Laboratory, San Diego, ... College of American Pathologists (CAP), based on results ... The laboratory,s director was advised of this national ... services being provided." GenWay Biotech Inc. GenWay Clinical ... nationwide. , The CAP Laboratory Accreditation Program, begun ...
(Date:12/15/2009)... ancient American horses may have been grazing the ... than previously thought. After plucking ancient DNA from ... researchers used cutting-edge techniques to uncover "genetic fossils" ... to between 7,600 and 10,500 calendar years. This ... of these now-extinct mammals endured longer in the ...
Breaking Biology News(10 mins):Late-surviving megafauna exposed by ancient DNA in frozen soil 2Late-surviving megafauna exposed by ancient DNA in frozen soil 3Late-surviving megafauna exposed by ancient DNA in frozen soil 4Industry Leaders Will Gather to Discuss the Future of the 26quot 3BHydrogen Economy 26quot 3B in Washington DC 12806 1Industry Leaders Will Gather to Discuss the Future of the 26quot 3BHydrogen Economy 26quot 3B in Washington DC 12806 2CareFusion Names Robert Friel to Board of Directors 50196 1CareFusion Names Robert Friel to Board of Directors 50196 2CareFusion Names Robert Friel to Board of Directors 50196 3A Random Act of Kindness Changes a Familys Life Forever as Alexzander Prados Wish to Walk is Granted at Abilities Expo 50194 1A Random Act of Kindness Changes a Familys Life Forever as Alexzander Prados Wish to Walk is Granted at Abilities Expo 50194 2A Random Act of Kindness Changes a Familys Life Forever as Alexzander Prados Wish to Walk is Granted at Abilities Expo 50194 3
... result in many differentially expressed genes that are ... In order to identify biological similarities between genes, ... of gene names and combinations of gene name ... strings for 15,621 known genes and 3,731 keywords ...
... have shown that "vascular stents" used to repair arteries ... mimic tiny features found in living tissues. , The ... that bone and cartilage cells in petri dishes attach ... are found on conventional materials used to make artificial ...
... cancer the opportunity to have children when chemotherapy and radiation ... of Michigan Comprehensive Cancer Center have found. , By having ... can preserve the hope of one day having a baby. ... they can lead to pregnancy is the challenge. In the ...
Other Biology News:Nano-bumps could help repair clogged blood vessels 2Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment 2Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment 3
(Date:12/17/2009)... develop proprietary medical food, functional food, and dietary supplement products ... , ... North Brunswick, NJ and ... biotechnology company at the crossroads of foods and pharmaceuticals, and ... to announce the signing of a Memorandum of Understanding (MOU) ...
(Date:12/16/2009)... cheap, accurate test to find undetected landmines. , Students ... bacteria that glows green when it comes into contact ... can be mixed into a colourless solution that, when ... indicate the presence of landmines. , Researchers say ... be delivered from the air onto areas thought to ...
(Date:12/16/2009)... that certain cardiac pacemakers may inadequately stimulate a ... (MRI) scan due to the magnetic pulses mixing ... This inadequate stimulation is potentially dangerous for the ... published in BioMed Central,s open access journal ... imaging technique that uses a magnetic field instead ...
(Date:12/16/2009)... months after the Nanyang Technological University (NTU) signed ... National Center for Scientific Research (CNRS) and the ... joint research laboratory, the three parties are meeting ... Alliance (CINTRA) Laboratory at NTU. , Located ... aims to harness the latest in science and ...
Breaking Biology Technology:WellGen, Inc. and RFI Ingredients to Collaborate on Therapeutic Nutrition Opportunities 2WellGen, Inc. and RFI Ingredients to Collaborate on Therapeutic Nutrition Opportunities 3FDA researchers identify new MRI safety risk for patients with pacemakers 2New Singapore-French nanotech lab opens at NTU 2New Singapore-French nanotech lab opens at NTU 3
... 11 The new Pearl(TM) In Vivo,Imaging System ... superior,near-infrared (NIR) results in less than 30 seconds. ... IRDye(R) Infrared Dyes, the proven performers,for NIR imaging ... images are acquired in 30 seconds," says,Jeff Harford, ...
... Mich., June 12 Neogen Corporation,(Nasdaq: NEOG ) ... and,development efforts for its new fiscal year, which began ... fall., "The organizational structure of our research and ... However, as we now,plan to double our revenues toward ...
... Symbol: MS, EDMONTON, June 12 /PRNewswire-FirstCall/ - BioMS Medical Corp ... today,announced that Mr. Kevin Giese, President and CEO, will present at ... WHEN: ... San Diego ...
Other Biology Technology:LI-COR Biosciences Introduces Near-Infrared Small Animal Imager 2Neogen Plans to Double R&D Staff, Efforts 2BioMS Medical to present at 2008 BIO International Convention 2
Cell Culture Flask, 75 cm, treated polystyrene...
... These 50ml PYREX Delong style shaker flasks ... provide greater agitation of solutions to improve ... rotary or reciprocating shakers. The long neck ... polypropylene closures. Their uniform wall thickness provides ...
... The Luminex 100 IS System is a ... laboratory that integrates lasers, optics, fluidics, a controller, ... reader. This powerful, compact lab analysis system includes ... SD. Also, it has a DMF file at ...
... nutritious peptone, used in ... of bacterial toxins, and ... bacteria with high nutritional ... Neisseria, Pasteurella, Salmonella and ...
Biology Products: