Navigation Links
Why is the heart heart-shaped?

How does the heart attain its characteristic shape? Shape may be sculpted by cell movement, cell division, or changes in cell size and shape, all of which can be influenced by the local environment. The heart appears as a simple tube early in development; later, the tube walls bulge outward to form the cardiac chambers.

In a new study published online in the open access journal PLoS Biology, Heidi Auman, Deborah Yelon, and colleagues found, by using transgenic zebrafish in which they can watch individual cardiac cells, that cells change size and shape, enlarging and elongating to form the bulges in the heart tube and eventually the chambers. Since the heart is beating as it develops, they asked whether cardiac function influences cell shape. Using zebrafish mutants with functional defects, they found that both blood flow and cardiac contractility influence cardiac cell shape. The researchers propose that a balance of the cell’s internal forces (through contractility) with external forces (such as blood flow) is necessary to create the cell shapes that generate chamber curvatures. Disruption of this balance may underlie the aberrations observed in some types of heart disease.


'"/>

Source:Public Library of Science


Page: 1

Related biology news :

1. UCSD team discovers specialized, rare heart stem cells in newborns
2. Single stem cells from bone heal a broken heart
3. Python a hearty eater
4. Columbia study shows widely used artery clearing device does not help patients during heart attack
5. Researchers reveal secret of key protein in brain and heart function
6. Stem cell therapy successfully treats heart attack in animals
7. New defibrillator signals doctor of patients irregular heartbeat or device malfunction
8. Survival of heart patients on beta-blockers varies greatly with genetic variation
9. Chemical band-aid prevents heart failure in mice with muscular dystrophy
10. MicroRNA tweaks protein that controls early heart development
11. Ibruprofen and other commonly used painkillers for treating inflammation may increase the risk of heart attack
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/20/2016)... 2016 Securus Technologies, a leading provider ... public safety, investigation, corrections and monitoring announced that ... has secured the final acceptance by all three ... Access Systems (MAS) installed. Furthermore, Securus will have ... installed by October, 2016. MAS distinguishes between legitimate ...
(Date:6/9/2016)... leader in attendance control systems is proud to announce the introduction of fingerprint attendance ... the right employees are actually signing in, and to even control the opening of ... ... ... Photo - ...
(Date:6/3/2016)... LONDON , June 3, 2016 /PRNewswire/ ... Transport Management) von Nepal ... ,Angebot und Lieferung hochsicherer geprägter Kennzeichen, einschließlich ... weltweit führend in der Produktion und Implementierung ... an der Ausschreibung im Januar teilgenommen, aber ...
Breaking Biology News(10 mins):
(Date:6/27/2016)... ... June 27, 2016 , ... ... findings on what they believe could be a new and helpful biomarker for ... research. Click here to read it now. , Biomarkers are components ...
(Date:6/27/2016)... 27, 2016   Ginkgo Bioworks , a leading ... was today awarded as one of the World ... world,s most innovative companies. Ginkgo Bioworks is engineering ... real world in the nutrition, health and consumer ... with customers including Fortune 500 companies to design ...
(Date:6/23/2016)... Seattle, WA (PRWEB) , ... June 23, 2016 ... ... technology, announces the release of its second eBook, “Clinical Trials Patient Recruitment and ... patient recruitment and retention in this eBook by providing practical tips, tools, and ...
(Date:6/23/2016)... , June 23, 2016 Houston Methodist ... the Cy-Fair Sports Association to serve as their ... agreement, Houston Methodist Willowbrook will provide sponsorship support, ... connectivity with association coaches, volunteers, athletes and families. ... the Cy-Fair Sports Association and to bring Houston ...
Breaking Biology Technology: