Navigation Links
Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.

Few things about growing older are as inevitable and obvious as “going gray,?yet scientists have been unable to explain the precise cause of this usually unwelcome transformation. In a report posted today on the Web site of the journal Science, researchers from Dana-Farber Cancer Institute and Children’s Hospital Boston say they have found the cellular cause of graying hair while investigating the origins of malignant melanoma, the potentially deadly skin cancer.

The scientists traced the loss of hair color to the gradual dying off of adult stem cells that form a reservoir that spawns a continuous supply of new pigment-manufacturing cells, called melanocytes, that give hair its youthful hues. Not only do the non-specialized stem cells become depleted, they also progressively make errors, turning into fully committed pigment cells in the wrong place within the hair follicle, where they are useless for coloring hair. The new findings won’t lead to a scientific alternative to hair dyes any time soon, if ever, even if they do solve a longstanding puzzle about the underlying mechanism of graying. Of more interest to the researchers is the pattern of cellular signals that triggers the death of pigment stem cells, since melanoma is dangerous for the opposite reason –melanocytes proliferate uncontrollably to form tumors and are hard to kill with treatment. “Preventing the graying of hair is not our goal,?emphasizes David E. Fisher, MD, PhD, director of the Dana-Farber Program in Melanoma, and senior author of the Science paper. “Our goal is to prevent or treat melanoma, and to the extent this research is revealing the life cycles of melanocytes, which are the cells that become cancerous in melanoma, we would love to identify a signal that would make a melanoma cell stop growing.?Fisher and the report’s lead author, Emi K. Nishimura, MD, PhD, also of the melanoma program, are in the Department of Pediatric Oncology at Children’s Hospital Boston as well as at Dana-Farb
'"/>

Source:


Page: 1 2 3

Related biology news :

1. Weizmann Institute suggests that immune cells help to maintain cognition and brain cell renewal
2. Weizmann Institute scientists discover a molecular security mechanism for keeping mutations in check
3. Affymetrix and the Karolinska Institutet Announce Translational Medicine Strategic Alliance
4. BioMed Central welcomes the new National Institutes of Health public access policy
5. Institute for Systems Biology Symposium Addresses Need for Better Computational Tools
6. Virginia Tech, Nanjing Institute researchers discover half-billion year-old fossils
7. UC San Diego partners with Venter Institute to build marine microbial genomics cyberinfrastructure
8. Virginia Bioinformatics Institutes launches microbial database
9. Latest advances in DNA sequencing highlighted at DOE Joint Genome Institute User Meeting
10. UCLA AIDS Institute researchers find a peptide that encourages HIV infection
11. Wisconsin scientists grow critical nerve cells
Post Your Comments:
(Date:9/30/2014)... research, involving mice and published in the October 2014 ... , suggests that just because you can do ... team of Italian scientists have found that using marijuana ... immune system. This damage may result in autoimmune diseases ... bowel disease and rheumatoid arthritis in adulthood. , "I ...
(Date:9/30/2014)... some hope: A new research report published in October ... , explains how scientists developed a synthetic version of ... development in human and mouse eggs similar to the ... during fertilization. , "We believe that the results of ... understanding of human fertilization by providing a precise answer ...
(Date:9/30/2014)... of perilous threats in today,s ocean. From overfishing ... fragile coral ecosystems are disappearing at unprecedented rates ... of corals surrounding the island of Moorea in ... tropical environment: coral guard-crabs. New research from the ... scientist Seabird McKeon and the museum,s predoctoral fellow ...
Breaking Biology News(10 mins):Adolescent exposure to thc may cause immune systems to go up in smoke 2Synthetic sperm protein raises the chance for successful in vitro fertilization 2Smithsonian scientists discover coral's best defender against an army of sea stars 2
... of different cancers actually share something in common ?a molecular ... microRNA (miRNA) that target key cancer genes and promote malignant ... as an emerging class of gene regulators and may also ... , The study appears online in the Proceedings of ...
... have for the first time reconstructed the Darwinian evolution ... research was led by Joe Thornton, assistant professor of ... and Evolutionary Biology, and will be published in the ... can drive the evolution of complex molecular systems ?those ...
... UT Southwestern Medical Center ophthalmologists will be the first in ... to fix nearsightedness. , "Think of it as a contact ... who is inserting the new implantable collamer lens, or ICL, ... , The ICL can replace or reduce the need for ...
Cached Biology News:Common molecular 'signature' identified in solid tumors 2Common molecular 'signature' identified in solid tumors 3Evolution of 'irreducible complexity' explained 2New 'implanted contacts' designed to fix nearsightedness 2
(Date:9/30/2014)... Fla. , Sept. 30, 2014 CORD:USE ... pleased to announce that it has entered into an ... Inc. (Tianhe) which has licensed a series of patented technologies ... cells for possible clinical applications.  Tianhe is performing Phase ... and Spain using Tianhe,s Stem ...
(Date:9/30/2014)... Md., Sept. 30, 2014 BioHealth Innovation, ... commercializing market-relevant biohealth innovations and increasing access to early-stage ... today that venture capitalist, Tania Fernandez , Ph.D., ... Dr. Fernandez will be a member of the management ... provide up to $50 million in seed and early-stage ...
(Date:9/30/2014)... September 30, 2014 Lyme Research ... of Lyme disease research at universities, today announced the ... on the identification, treatment and cure for Lyme and ... received the most applications in its history—over 20 grant ... “While we were pleased to receive so many solid ...
(Date:9/30/2014)... Whitehouse Laboratories is pleased ... Parenteral Drug Association (PDA) to host a ... container closure integrity testing. This lecture/laboratory course will examine ... philosophies detailed in the recently proposed revision to USP ... course will span container closure integrity testing (leak testing) ...
Breaking Biology Technology:CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 2CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 3CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 4Seasoned Life Sciences Venture Capitalist Tania Fernandez Joins BHI to Help Manage New BioHealth Gap Fund 2Lyme Research Alliance Awards Nearly $600,000 in New Grants 2Lyme Research Alliance Awards Nearly $600,000 in New Grants 3Lyme Research Alliance Awards Nearly $600,000 in New Grants 4Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 2Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 3Whitehouse Laboratories to Partner with PDA for Educational Course on Container Closure Integrity Testing 4
... breaches - ... - ... 29 Protein Sciences Corporation,("PSC") announced today that the sale of ... Inc. (NYSE: EBS ),and its affiliate (collectively "Emergent") has been ...
... 29 /PRNewswire-FirstCall/ - Par,Pharmaceutical Companies, Inc. (NYSE: PRX ... and live webcast on Friday, August 8, 2008 at ... ended June 28, 2008. The,Company will release results after ... release will be available on the Par website at, ...
... Event Expected to Attract a Record Number of ... ... DeviceSpace(TM), the world,s,leading online medical device and diagnostics job board ... Minnesota on,Monday, September 8, 2008. The event will take place at ...
Cached Biology Technology:Protein Sciences Announces Termination of Deal to Sell to Emergent BioSolutions 2DeviceSpace(TM) to Host Medical Device and Diagnostics Career Fair in Minneapolis 2
... from KUBTEC is a dual capability system with ... representation of the specimen under test. While the ... images, the micro focus source also allows the ... standard 2D images. The 50 mm x 50 ...
... electroporation products and specialty electrodes, has developed ... experiment optimization and large volume electroporation. The ... Molecular Delivery. The days of researchers struggling ... the number of samples and cell types ...
... (PR) Competitor Assay Kits are ideal ... receptor binding compounds using fluorescence polarization ... fusion of glutathione transferase to the ... receptor [PR-LBD(GST)] and a proprietary, fluorescently ...
... Kodak Companys Molecular Imaging Systems group ... Station 4000 Digital Imaging Systems, featuring ... for comprehensive fluorescence, luminescence, radiographic and ... million pixel CCD and 10x optical ...
Biology Products: