Navigation Links
'Virus chip' detects new virus in prostate tumors

UCSF and Cleveland Clinic scientists have discovered a new virus in human prostate tumors. The type of virus, closely related to viruses typically found in mice, has never been detected in humans. The virus's link to human disease is still unclear, and more study is needed to determine the relationship between the virus and cancer, if any, the scientists say.

The discovery was made with the same DNA-hunting "virus chip" used to confirm the identity of the SARS virus three years ago.

While the genetics of prostate cancer are complex, one of the first genes implicated in the disease was RNASEL, a gene that serves as an important defense against viruses. Given the anti-viral role of this gene, some scientists have speculated that a virus could be involved in some types of prostate cancers in men with mutated RNASEL genes.

In the new study, the researchers discovered the novel virus far more often in human prostate tumors with two copies of the RNASEL gene mutation than in those with at least one normal copy.

"This is a virus that has never been seen in humans before," said Eric Klein, MD, a collaborator in the research and head of urologic oncology at the Glickman Urologic Institute of Cleveland Clinic. "This is consistent with previous epidemiologic and genetic research that has suggested that prostate cancer may result from chronic inflammation, perhaps as a response to infection."

"The power of the virus chip resides in its ability to simultaneously screen for all viruses, without preconceptions or bias," said Joe DeRisi, PhD, a Howard Hughes Medical Institute (HHMI) investigator at UCSF who developed the chip with colleagues in his lab. "In the case of these prostate tissues, no one would have suspected a virus of this class." DeRisi is a UCSF associate professor of biochemistry and co-leader of the study with Don Ganem, MD, also an HHMI investigator at UCSF and a professor of microbiology and immunology.

Klein re
'"/>

Source:University of California - San Francisco


Page: 1 2 3

Related biology news :

1. Cardiologists living chip changes science of disease monitoring
2. MIT designs portable lab on a chip
3. Novel technology detects human DNA mutations
4. Robot-based system developed at Carnegie Mellon detects life in Chiles Atacama desert
5. New technique rapidly detects illness-causing bacteria
6. Olfactory system detects pheromones that control reproduction
7. Sports cheats beware -- new test detects previously undetectable drug
8. Fast test for low blood flow in dogs detects early heart trouble
9. Newly identified biomarker detects and regulates spread of brain tumors
10. New sensor detects gaseous chemical weapon surrogates in 45 seconds
11. A new portable biosensor detects traces of contaminants in food more quickly and cheaply
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Virus chip detects new virus prostate tumors

(Date:7/10/2014)... The Marshall Institute for Interdisciplinary Research (MIIR) ... of Medicine today announced they will be partnering ... anti-cancer drugs. , Under the agreement with Shanghai-based ... share the costs and risks of discovery and ... jointly own any intellectual property and commercialization rights ...
(Date:7/10/2014)... controversy centres around a family of enzymes known as ... group in their active site. At the centre of ... becomes oxidised (ferryl) when a reacting heme is in ... has remained unanswered for decades is whether this oxidation ... group (OH). Resolving this fundamental question has implications for ...
(Date:7/10/2014)... GOES-West satellite spotted smoke over the U.S. Mid-West ... Territories. , At 1200 UTC (8 a.m. EDT) ... of the brownish-colored haze created by forest fires ... way into South Dakota. This image was created ... Space Flight Center, Greenbelt, Md. , According ...
Breaking Biology News(10 mins):Marshall University to partner with international company in drug development venture 2Neutron crystallography solves long-standing biological mystery 2Neutron crystallography solves long-standing biological mystery 3
... rivals the honeybees to learn where the best food resources ... London. Writing in the journal PLoS ONE , ... Sciences explain how they trained a colony of bumblebees ( ... species, the honeybee ( Apis mellifera ), as well as ...
... the University of Melbourne shows how the malaria parasite ... before sexual reproduction, a finding that could provide targets ... the parasite evades the human immune system. The ... by Dr Matthew Dixon and PhD student Megan Dearnley ...
... tool has been developed to improve the accuracy and extent ... ,Geo-Wiki, uses Google Earth and information provided by a ... to verify existing land cover information. Developers this week have ... and to encourage community involvement in environmental monitoring. ...
Cached Biology News:Bumblebees get by with a little help from their honeybee rivals 2Malaria parasite goes bananas before sex: New study 2New web tool to improve accuracy of global land cover maps 2New web tool to improve accuracy of global land cover maps 3New web tool to improve accuracy of global land cover maps 4
(Date:7/10/2014)... According to the International Atomic Energy Agency (IAEA) ... terrorists acquiring sufficient quantities of plutonium or highly ... explosive device. The IAEA also notes that most ... quantities, which can be challenging to detect with ... study appearing this week in the Journal ...
(Date:7/10/2014)... D.C., June 17, 2014 Using microscopic polymer ... specific gases, researchers at MIT,s Quantum Photonics Laboratory ... levels in the parts-per-billion range. Optical sensors are ... their high signal-to-noise ratio, compact, lightweight nature, and ... gas sensors had been developed before, the MIT ...
(Date:7/10/2014)... the basis of psychiatric disorders has been extremely challenging ... risk but are insufficient to cause disease. Now investigators ... Press journal Cell Stem Cell describe a ... risks interact with other risk factors or environmental exposures ... research pinpoints a genetic variant that may predispose individuals ...
(Date:7/10/2014)... The lithium-ion batteries that power our laptops and ... on a single charge with the help of a ... material to replace the graphite traditionally used in one ... 10 times the energy storage capacity of graphite. A ... electrode was published today in Nature Communications . ...
Breaking Biology Technology:Sensitive detection method may help impede illicit nuclear trafficking 2Swell new sensors 2New strategy could uncover genes at the root of psychiatric illnesses 2Silicon sponge improves lithium-ion battery performance 2Silicon sponge improves lithium-ion battery performance 3
... KONG, Nov. 22, 2011 SuperNova Diagnostics®, Inc., a privately-held ... announced that Neil J. Campbell, President and CEO, will ... Conference on November 30, 2011 at 10:30 a.m. ET ... New York. The presentation will include an ...
... DIEGO, Nov. 22, 2011 Sequenom, Inc. (NASDAQ: ... solutions, today announced the Company,s participation at the 23rd Annual ... York City November 29-30, 2011. Ronald M. ... Paul V. Maier, CFO, will present on Tuesday, November 29, ...
... (Italy), November 21, 2011. CNR Rao, Linus Pauling research ... for Advanced Scientific Research and immediate past president of ... has been named the winner of the 2011 Ernesto ... is designed to give international recognition and visibility to ...
Cached Biology Technology:SuperNova Diagnostics® to Present at the 23rd Annual Piper Jaffray Healthcare Conference in New York City 2Sequenom Announces Participation at the 23rd Annual Piper Jaffray Healthcare Conference 2CNR Rao wins 2011 Ernesto Illy Trieste Science Prize 2CNR Rao wins 2011 Ernesto Illy Trieste Science Prize 3CNR Rao wins 2011 Ernesto Illy Trieste Science Prize 4
Request Info...
Buffer used for mitocapture assays....
... Our entry-level automated perfusion system. For ... perfusion, physiology, biophysics, electrochemistry, or general ... with 10 millisecond accuracy Run ... Microprocessor-based for accuracy and flexibility ...
{3,8-diamino-5-[3-(diethylmethylammonio)propyl]-6-phenylphenanthridinium diiodide}. ,250 ug/ml Propidium Iodide (PI) in PBS....
Biology Products: