Navigation Links
Virginia Tech's System X supercomputer provides super tool for simulation of cell division

Virginia Tech researchers in computer science and biology have used the university's supercomputer, System X, to create models and algorithms that make it possible to simulate the cell cycle -- the processes leading to cell division. They have demonstrated that the new mathematical models and numerical algorithms provide powerful tools for studying the complex processes going on inside living cells.

Biologist John Tyson, who studies the cell cycle, is a leader in applying mathematical models in molecular cell biology. However, comparing the results of a mathematical model to experimental data is difficult because mathematical results are quantitative (numbers) while much experimental data is qualitative (trends). The mathematical biologist must figure out how to set the numerical values of the ‘parameters’ in the model equations in order to create an accurate representation of what is going on inside the cell. A simple example is the conversion between Fahrenheit and Celsius temperatures, said mathematician Layne Watson. "You could use several pairs of Fahrenheit and Celsius readings for the same temperature, and try to deduce the formula for converting between the temperature scales."

Previously, Tyson worked with simpler models whose parameters could be determined by trial and error, a process modelers call "parameter twiddling." But he and his coworker, Kathy Chen, wanted to characterize all the protein interactions regulating the cell cycle of budding yeast (the yeast cells familiar to bakers and brewers, and a favorite organism of molecular biologists, as well). "Such fundamental research on the cell cycle of budding yeast provides a basis for understanding the reproduction of human cells and is relevant to the causes and treatment of cancer, to tissue regeneration, and to the control of many pathogens," Tyson said.

For the budding yeast cell cycle, the experimental data consists of observed traits of 130 mutant yeast strains cons
'"/>

Source:Virginia Tech


Page: 1 2 3

Related biology news :

1. Virginia Tech group adds tools to DNA-targeted anti-cancer drugs
2. Virginia Tech, Nanjing Institute researchers discover half-billion year-old fossils
3. Virginia Tech football player uses prototype cast
4. Virginia Tech scientists develop process for creating biocompatible fibers
5. Virginia Tech helping to develop higher quality, disease-resistant wheat varieties
6. Virginia Bioinformatics Institutes launches microbial database
7. Genes In The Interferon System Important In Systemic Lupus Erythematosus
8. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
9. Transport System Smuggles Medicines Into Brain
10. PANTHER Protein Classification System Database 5.0
11. Institute for Systems Biology Symposium Addresses Need for Better Computational Tools
Post Your Comments:
(Date:12/17/2014)... 16, 2014 Valencell, a leader in performance ... technology to industry leaders such as Intel, Jabra, Atlas, ... biometric wearable products. These products will be showcased at ... Las Vegas . "Our partners ... and robust – with the clinical data to back ...
(Date:12/17/2014)... 2014  Automation is fundamentally transforming the travel ... at international borders. Over the past decade, ePassports, ... veteran travelers to self process through border control ... at an increasing number of airports, seaports, and ... According to Maxine Most , Principal at ...
(Date:12/11/2014)... 2014 Research and Markets ... ( http://www.researchandmarkets.com/research/twhjll/biometrics_market ) has announced the addition of ... 2015-2019"  report to their offering. ... advances in technology. With continuous advances in technology, ... the latest standard that meets the needs and ...
Breaking Biology News(10 mins):Valencell PerformTek Biometrics Power the Most Accurate Wearables at CES 2015 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2Biometrics Market in the APAC Region 2015-2019: Key Vendors are 3M Cogent, NEC, Safran and Suprema 2
... GAINESVILLE, Fla. While studying a way to ... Florida researchers have noticed the venom delivered by an ... in response to their diet. Scientists used a ... producing more consistent extraction results and greater amounts of ...
... workshop on male infertility in Thessaloniki, Greece "Reproductive andrology: ... provides a forum for clinicians and scientists to share ... some of the new research findings that fertility experts ... Nature versus Nurture: Male reproductive disorders ...
... chloride, a component of salt, are elevated in many urban ... new government study. Chloride levels above the recommended federal ... than 40 percent of urban streams tested. The study ... Elevated chloride can inhibit plant growth, impair reproduction, and reduce ...
Cached Biology News:Study of isolated snakes could help shed light on venom composition 2Study of isolated snakes could help shed light on venom composition 3Chloride found at levels that can harm aquatic life in urban streams of the Northern US 2
(Date:12/17/2014)... (PRWEB) December 17, 2014 Gene ... that it has entered into a technology access ... (ADM) to apply DNA2.0’s proprietary protein engineering technology, ... process. , “We are extremely excited that the ... platform. This proprietary bioengineering technology has now ...
(Date:12/17/2014)... SOUTH SAN FRANCISCO, Calif. , Dec. 17, ... positive results of a Phase 2 study evaluating ... for the treatment of patients with severe, chronic ... the current standard of care, including topical steroids ... endpoint was percent change in Visual Analog Scale ...
(Date:12/15/2014)...  GlassesOff Inc. (OTCBB: GLSO) announced today the appointment ... director of the Company,s Board of Directors. ... its CEO until its acquisition by Stanley Black ... Recognized as the inventor of the first Wi-Fi-based Active ... -based RFID solutions focused on improving operational efficiency, safety ...
(Date:12/13/2014)... (PRWEB) December 12, 2014 Clarassance, a ... announced its new name: Therabron Therapeutics , Inc. ... and bronchioles (a type of structure in the lungs ... company’s mission to develop novel protein therapeutics for the ... directors decided to change the name to mark the ...
Breaking Biology Technology:ADM and DNA2.0 Enter Into Protein Engineering Technology Access and Service Agreement 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 2Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 3Velocity Pharmaceutical Development, LLC and Tigercat Pharma, Inc. Announce Phase 2 Results for VPD-737 in Patients With Chronic Pruritus 4AeroScout Founder Joins GlassesOff's Board of Directors 2AeroScout Founder Joins GlassesOff's Board of Directors 3Maryland-based Biotech Company's Path Forward in Treating Respiratory Diseases Sparks Name Change 2
... Open, EL SEGUNDO, Calif., Oct. 1 DaVita ... in the United States, is,caring for thousands of dialysis ... in the Houston area. DaVita,s Emergency Response Team,had hundreds ... vital dialysis treatment during and after the storm. Nearly ...
... Test is Cepheid,s Second FDA Cleared Diagnostic Test in 2008; Test, ... ... Methods, SUNNYVALE, Calif., Oct. 1 Cepheid ... Drug,Administration (FDA) to market its Xpert(TM) MRSA/SA Blood Culture (BC),test, which runs ...
... of 2008 R&D 100 Awards Now Online, ROCKAWAY, ... for the 8th Annual Innovator of the Year and ... who exemplify the,ideals of R&D in academia, industry, and ... online with ten finalists,-- five scientists and five innovators ...
Cached Biology Technology:DaVita Treats Thousands of Dialysis Patients in Wake of Hurricane Ike 2Cepheid Receives FDA Clearance for First On-Demand Diagnostic Test for Life-Threatening MRSA and Staphylococcus aureus From Patient Positive Blood Cultures 2Cepheid Receives FDA Clearance for First On-Demand Diagnostic Test for Life-Threatening MRSA and Staphylococcus aureus From Patient Positive Blood Cultures 3Cepheid Receives FDA Clearance for First On-Demand Diagnostic Test for Life-Threatening MRSA and Staphylococcus aureus From Patient Positive Blood Cultures 4Cepheid Receives FDA Clearance for First On-Demand Diagnostic Test for Life-Threatening MRSA and Staphylococcus aureus From Patient Positive Blood Cultures 52008 R&D Innovator of the Year & Scientist of the Year Finalists Announced 2
Anti-MT3-MMP Membrane-Type Metalloproteinase-3; propeptide domain; rabbit host...
Rabbit polyclonal to Methionine Aminopeptidase 2 ( Abpromise for all tested applications). entrezGeneID: 10988 SwissProtID: P50579...
Mouse monoclonal [TU-20] to beta III Tubulin (FITC) ( Abpromise for all tested applications). entrezGeneID: 10381 SwissProtID: Q13509...
Chlamydia pneumoniae (TWAR)...
Biology Products: