Navigation Links
Virginia Tech scientists develop process for creating biocompatible fibers

Scientists at Virginia Tech have developed a single-step process for creating nonwoven fibrous mats from a small organic molecule ?creating a new nanoscale material with potential applications where biocompatible materials are required, such as scaffolds for tissue growth and drug delivery.

The research will be presented in the Jan. 20 issue of Science, in the article, "Phospholipid Nonwoven Electrospun Membranes," by Matthew G. McKee, a recent Ph.D. graduate in chemical engineering from Virginia Tech now at P&G, current chemistry students John M. Layman and Matthew P. Cashion, and chemistry professor Timothy E. Long, all at Virginia Tech.

"Phospholipids, which are the main component of cell membranes in the human body or in an apple are exquisite in terms of their ability to self-organize," said Long.

The researchers fabricated this natural compound into a sub micron fiber ?100 times smaller than a human hair. "It is the first demonstration that electrostatic spinning, or electrospinning, a polymer processing technique, can be used with a small molecule to produce a fiber. "Clothing fibers such as polyesters and nylons are composed of large molecules, macromolecules," Long said. "Now, we are fabricating fibers from small molecules ?ones with a low molecular weight."

Under the microscope, the resulting mat shows a porous nonwoven structure.

The researchers used a commercial product, lecithin, a natural mixture of phospholipids and neutral lipids. The materials will spontaneously organize into cylindrical or worm-like strands to form membranes.

McKee studied this self-assembly and conducted rheological experiments to fundamentally understand the association of small molecules, then he determined that once phospholipids form an entangled network they can be treated similarly to higher weight molecules and electrospun. The size of the mats is limited only by the amount of material, such as lecithin.

"This re
'"/>

Source:Virginia Tech


Page: 1 2

Related biology news :

1. Virginia Tech group adds tools to DNA-targeted anti-cancer drugs
2. Virginia Tech, Nanjing Institute researchers discover half-billion year-old fossils
3. Virginia Tech football player uses prototype cast
4. Virginia Tech helping to develop higher quality, disease-resistant wheat varieties
5. Virginia Bioinformatics Institutes launches microbial database
6. Virginia Techs System X supercomputer provides super tool for simulation of cell division
7. Wisconsin scientists grow critical nerve cells
8. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
9. UAB scientists discover the origin of a mysterious physical force
10. Fox Chase Cancer Center scientists identify immune-system mutation
11. Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.
Post Your Comments:
(Date:9/30/2014)... JOLLAJoseph Ecker, a Salk professor and Howard Hughes ... scientist, have been named recipients in the 2014 ... Health (NIH) through the BRAIN (Brain Research through ... neuroscience. The grant, announced September 30, provides more ... scientists over three years. , The BRAIN Initiative, ...
(Date:9/30/2014)... reports positive results of a phase 1 clinical ... lung cancer marked by rearrangement of the gene ROS1. ... non-small cell lung cancer testing positive for ROS1 gene ... complete responses and 33 partial responses. Median progression-free survival ... resume its growth after being slowed by treatment ...
(Date:9/30/2014)... urban and farm runoff in Hawaii is causing tumors ... , The study, published Tuesday in the peer-reviewed open-access ... runoff ends up in algae that the turtles eat, ... flippers and internal organs. , Scientists at Duke University, ... Atmospheric Administration (NOAA) conducted the study to better understand ...
Breaking Biology News(10 mins):Salk scientists receive $3 million for BRAIN Initiative grant 2NEJM: Crizotinib effective in Phase 1 trial against ROS1 lung cancer 2Pollution linked to lethal sea turtle tumors 2Pollution linked to lethal sea turtle tumors 3
... Institute (Germany) and the ESRF have just discovered the ... bone by studying it with the synchrotron X-rays. This ... The hierarchical structure of bones makes them able to ... essentially rigid units at the molecular level. The re-sults ...
... of California, San Diego have discovered that the presence of ... fly (which glow at center due to a fluorescent protein) ... of its 800 unit eyes, an evolutionary change to an ... visual acuity and angular sensitivity. In contrast, beetles (shown surrounding ...
... By sampling different ocean locations for the presence of ... gained new insight into the dwelling places of the ... The symbiosis between special algal species and reef corals ... complex ecosystem, but our understanding of how this symbiosis ...
Cached Biology News:Bones at the nanoscale 2Ocean sampling yields environmental sources of coral symbionts 2
(Date:9/30/2014)... Proove Biosciences , the commercial ... announce a new genetic test built upon research from ... Test will provide physicians with an objective way ... levels are stratified between individuals. With this new test, ... has a genetic predisposition that will affect their pain ...
(Date:9/30/2014)... , Sept. 30, 2014 CORD:USE Cord ... to announce that it has entered into an Equity ... (Tianhe) which has licensed a series of patented technologies for ... for possible clinical applications.  Tianhe is performing Phase I/II ... Spain using Tianhe,s Stem Cell ...
(Date:9/30/2014)... Angeles, CA (PRWEB) September 30, 2014 ... (EWS), the high-speed, chemical-free process to clean up large ... to shareholders, CEO Riggs Eckelberry reported on the launch ... Texas, at a site provided by partner STW ... up to 1000 barrels per day (bpd) and achieved ...
(Date:9/30/2014)... 2014 FemCap Inc., www.femcap.com  an innovator ... of a patent No: US, 8,795,248 B2 dated Aug. ... FDA clearance in the U.S., 510(K) K121857, medical device ... patent is related to its menstrual cup with a ... is releasing FemmyCycle Teen, a third menstrual cup to ...
Breaking Biology Technology:Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 2Proove Biosciences is Now Offering the Proove Pain Perception Genetic Test to Help Physicians Assess Patient Pain Tolerance Levels 3CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 2CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 3CORD:USE is Pleased to Announce it has Partnered with Tianhe Stem Cell Biotechnologies, Developer of Cord Blood Stem Cell Therapy Showing Promising Results in Clinical Trials for the Treatment of Diabetes and Autoimmune Diseases 4OriginOil, Inc. Report to Shareholders: Blue Gold in West Texas 2The FemmyCycle 2
... in developing a new material using nano-sized magnets that could ... capacity than is currently feasible, in a study published today ... modern data storage devices, like hard disk drives, rely on ... sections, but their overall design is limited by the way ...
... mobile bio-containment laboratory is now stationed in the Mexican ... The US-built lab provides new early warning capabilities for ... kind in Latin America. (Photo:  http://photos.prnewswire.com/prnh/20120329/FL78689 ... of technology being utilized on the front lines of ...
... Marshall Hicks, M.D., FSIR, an interventional radiologist and ... University of Texas MD Anderson Cancer Center in Houston, ... of Interventional Radiology during its 37th Annual Scientific Meeting ... of nearly 5,000 scientists and allied health professionals dedicated ...
Cached Biology Technology:Honeycombs of magnets could lead to new type of computer processing 2Honeycombs of magnets could lead to new type of computer processing 3US Lab Deployed to Boost Mexico's Response to Outbreaks of Infectious Disease 2Society of Interventional Radiology Names Marshall Hicks, M.D., FSIR, as 2012-13 President 2Society of Interventional Radiology Names Marshall Hicks, M.D., FSIR, as 2012-13 President 3
Mouse Anti-Human Kallikrein 2 (Hk2)...
Rabbit polyclonal to Dishevelled 2 ( Abpromise for all tested applications). entrezGeneID: 1856 SwissProtID: O14641...
Presenilin 2 Immunogen: Synthetic peptide corresponding to residues 31-47 of human Presenilin 2. Storage: -20 C, Avoid Freeze/Thaw Cycles...
Monoclonal Anti-Gα o purified immunoglobulin buffered aqueous solution Solution in phosphate buffered saline pH 7.4, containing 0.08% sodium azide. partially purified bovine brain Gα O ...
Biology Products: