Navigation Links
Viral marker of human migration suspect

A benign virus previously used as a marker in tracing human migration may be unreliable, according to researchers at Penn State. Results of this study also suggest that some viruses might be undergoing much higher rates of evolution than previously thought.

"The most genetically divergent human populations are in Africa," said Laura Shackelton, a postdoctoral researcher at Penn State's Center for Infectious Disease Dynamics. "But, in the case of this virus, strains from European communities appear to be the most divergent."

The human polyomavirus, or JCV, is a small double-stranded DNA virus that is thought to be primarily transmitted from parents to their children. Infection is usually asymptomatic unless a person has a weak immune system, in which case the virus can cause neurological disease.

There are more than 14 subtypes of the virus, each primarily associated with different human populations such as African, Japanese, South Asian, and European. Population geneticists have assumed that the virus has been with humans since their emergence from Africa.

"Because of this presumed codivergence with human populations, JCV has been widely used as a genetic marker for human evolution and migration," explained Shackelton, whose findings appear this month (October) in the Journal of Virology.

The researchers note that while previous studies of genetic variation have observed some differences between the distribution of JCV and human populations, the extent of the differences in their evolutionary histories has never been fully tested.

Shackelton and her colleagues analyzed 333 genetic sequences of the virus and reconstructed their evolutionary history. They then compared this history to the reconstructed history of human populations, based on mitochondrial DNA.

"If the virus had been with humans since we were a single population, and we have almost strictly transmitted it to our children, you may exp
'"/>

Source:Penn State


Page: 1 2

Related biology news :

1. Viral DNA sequence a possible trigger for breast cancer
2. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
3. Viral protein influences key cell-signaling pathway
4. Viral protein helps infected T cells stick to uninfected cells
5. Viral fitness explains different resistance patterns to aids drugs
6. Viral genetic differences are possible key to HIV dementia
7. Viral hitchhiker inhibits Wolbachia bacterias ability to proliferate
8. Viral protein is an effective preventative against infection
9. Biomarkers isolated from saliva successfully predict oral and breast cancer
10. UCLA cancer researchers shake loose hidden biomarker
11. Measurement Challenges In Detecting Cancer Biomarkers
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Viral marker human migration suspect

(Date:8/31/2014)... study, published today in Nature Climate Change , suggests ... will reach, if not exceed, the global targets for total ... authors say we should all think carefully about the food ... diets across the world is just one of a number ... climate change and ensure there is enough food for all. ...
(Date:8/29/2014)... MISSOULA Until recently, little has been known about ... An international team of scientists, one of whom is ... breakthrough by showing that genes controlling the development of ... for rabbit domestication., The study was published Aug. 28 ... genetic questions. It is online at http://www.sciencemag.org/ ., ...
(Date:8/29/2014)... release is available in German . ... signals between organisms is considered the oldest form of ... between conspecifics, for example, the sexual attraction between males ... responses and to coordinate reproductive behavior in males and ... University of the Algarve in Faro, Portugal, and at ...
Breaking Biology News(10 mins):Changing global diets is vital to reducing climate change 2Changing global diets is vital to reducing climate change 3Changing global diets is vital to reducing climate change 4New research reveals how wild rabbits were genetically transformed into tame rabbits 2New research reveals how wild rabbits were genetically transformed into tame rabbits 3Ready for mating at the right time 2Ready for mating at the right time 3
... articles posted online between 10 Dec. and 21 Dec. ... America,s Geologic Time Scale. This paper marks the beginning of ... 125th Anniversary in 2013. Highlights are provided below. ... fossil record of the Gran Barranca, Patagonia, Argentina., 3. A ...
... (December 26, 2012)The Wildlife Conservation Society (WCS) announced ... across the big cat,s range due to better law ... The successes are much-needed good news as tiger ... to the combined threat of poaching, loss of prey, ...
... or nerve cells, embryonic stem cells are by definition equipped ... meaning that as an organism develops, stem cells must be ... expression programs used to turn them into blood, brain, or ... Investigator Ali Shilatifard, Ph.D., report in the December 27, 2012 ...
Cached Biology News:GSA Bulletin celebrates GSA's 125th Anniversary with new geologic time scale 2GSA Bulletin celebrates GSA's 125th Anniversary with new geologic time scale 3GSA Bulletin celebrates GSA's 125th Anniversary with new geologic time scale 4GSA Bulletin celebrates GSA's 125th Anniversary with new geologic time scale 5GSA Bulletin celebrates GSA's 125th Anniversary with new geologic time scale 6GSA Bulletin celebrates GSA's 125th Anniversary with new geologic time scale 7GSA Bulletin celebrates GSA's 125th Anniversary with new geologic time scale 8GSA Bulletin celebrates GSA's 125th Anniversary with new geologic time scale 9GSA Bulletin celebrates GSA's 125th Anniversary with new geologic time scale 10GSA Bulletin celebrates GSA's 125th Anniversary with new geologic time scale 11Tigers roar back: Good news for big cats in 3 key landscapes 2Tigers roar back: Good news for big cats in 3 key landscapes 3Stowers study hints that stem cells prepare for maturity much earlier than anticipated 2Stowers study hints that stem cells prepare for maturity much earlier than anticipated 3
(Date:9/2/2014)... Winston-Salem, NC and Rocky Mount, NC (PRWEB) September 02, ... (PMG) announced today the establishment of its 11th clinical ... 1, PMG Research has assumed ownership and operation of ... in Rocky Mount, NC, further expanding PMG’s presence in ... to an additional 130,000 patients. For the patients in ...
(Date:9/2/2014)... BETHESDA, Md. , Sept. 2, 2014  Spherix ... fostering and monetization of intellectual property, today announced that ... three patents to the Company in the month of ... of patents.  The issued patents are: ... , U.S.RE45,081 issued August 19, 2014; and ...
(Date:9/2/2014)... 2, 2014 Culot brings life ... lab management services  BioData, producer of Labguru, ... to announce the appointment of Louis Culot ... as VP Marketing and Business Development at BioDiscovery Inc., ... clinical applications. Previously, Culot worked for 17 ...
(Date:9/2/2014)... The inventors of tinAway, a novel treatment ... seeking support for development costs through a crowdfunding campaign. ... ), was launched on September 1, 2014. , tinAway ... is based on ten years of neuroscience research. ... software engineers, Dr. Ian Dixon and Mr. Tony Burgess, ...
Breaking Biology Technology:PMG Research Announces the Formation of its Eleventh Site 2PMG Research Announces the Formation of its Eleventh Site 3United States Patent & Trademark Office Issues Three New Standard Essential Patents to Spherix 2Louis Culot Appointed as BioData's CEO 2tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 2tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 3tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 4tinAway Pty. Ltd. launch a crowdfunding campaign to fund a clinical trial of tinAway, a new potential cure for chronic tinnitus 5
... reported a GAAP loss of $1.9 million, or five cents ... the company's quarterly revenues continue to rise. , ,Sonic Foundry, ... loss compares to a GAAP loss of $947,000, or three ... in the 2007 number is $395,000 in non-cash expenses for ...
... Assembly Speaker Mike Huebsch , R-West Salem, and State ... to serve on the Speaker's Task Force on Information Technology ... a number of failed information technology projects in state government, ... sectors. , ,In addition to Montgomery, who will serve as ...
... Milwaukee, Wis . - Ordinarily, the news that Wisconsin, which ... is losing one of its key venture capital firms would ... to spin off its venture capital business is being greeted ... ,The private equity firm, which has managed more than $500 ...
Cached Biology Technology:Eight lawmakers named to Speaker's IT task force 2Biotech officials praise focus of new venture fund 2Biotech officials praise focus of new venture fund 3
... is for 2-D separations. The cell has a ... II xi multi-cell can be customized for several ... and cooling system. The PROTEAN II xi multi-cell ... XL multi-cell for a wider format that accommodates ...
... depletion cocktail is tailored to ... suspensions of rat spleen cells. ... StemSep (or compatible 0.5 Tesla) ... T cell content of the ...
... 20 cm, is used for vertical slab gel ... gels. The cell is supplied without spacers and ... with gaskets, lower buffer chamber, lid with cables, ... upper buffer dam, casting stand with gaskets, leveling ...
...
Biology Products: