Navigation Links
Viral marker of human migration suspect

A benign virus previously used as a marker in tracing human migration may be unreliable, according to researchers at Penn State. Results of this study also suggest that some viruses might be undergoing much higher rates of evolution than previously thought.

"The most genetically divergent human populations are in Africa," said Laura Shackelton, a postdoctoral researcher at Penn State's Center for Infectious Disease Dynamics. "But, in the case of this virus, strains from European communities appear to be the most divergent."

The human polyomavirus, or JCV, is a small double-stranded DNA virus that is thought to be primarily transmitted from parents to their children. Infection is usually asymptomatic unless a person has a weak immune system, in which case the virus can cause neurological disease.

There are more than 14 subtypes of the virus, each primarily associated with different human populations such as African, Japanese, South Asian, and European. Population geneticists have assumed that the virus has been with humans since their emergence from Africa.

"Because of this presumed codivergence with human populations, JCV has been widely used as a genetic marker for human evolution and migration," explained Shackelton, whose findings appear this month (October) in the Journal of Virology.

The researchers note that while previous studies of genetic variation have observed some differences between the distribution of JCV and human populations, the extent of the differences in their evolutionary histories has never been fully tested.

Shackelton and her colleagues analyzed 333 genetic sequences of the virus and reconstructed their evolutionary history. They then compared this history to the reconstructed history of human populations, based on mitochondrial DNA.

"If the virus had been with humans since we were a single population, and we have almost strictly transmitted it to our children, you may exp
'"/>

Source:Penn State


Page: 1 2

Related biology news :

1. Viral DNA sequence a possible trigger for breast cancer
2. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
3. Viral protein influences key cell-signaling pathway
4. Viral protein helps infected T cells stick to uninfected cells
5. Viral fitness explains different resistance patterns to aids drugs
6. Viral genetic differences are possible key to HIV dementia
7. Viral hitchhiker inhibits Wolbachia bacterias ability to proliferate
8. Viral protein is an effective preventative against infection
9. Biomarkers isolated from saliva successfully predict oral and breast cancer
10. UCLA cancer researchers shake loose hidden biomarker
11. Measurement Challenges In Detecting Cancer Biomarkers
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Viral marker human migration suspect

(Date:12/11/2014)... , Dec. 10, 2014  Data Sciences International ... has released a new series of digital telemetry ... toxicology researchers. M series, part of the PhysioTel™ ... the best possible physiologic data when incorporating functional ... functional endpoints to toxicology studies has evolved from ...
(Date:12/10/2014)... , Dec. 9, 2014  Wake Forest Baptist Medical Center ... for its School of Medicine. Funding for this $50 ... campaign that will be publicly launched next summer. ... in the former 60 series R.J. Reynolds Tobacco Company ... Construction will begin immediately with plans to be ready ...
(Date:12/10/2014)... California , December 9, 2014 ... with ITN,s BCARD Platform   ... cloud-based enterprise meeting scheduling solutions for business-to-business (B2B) ... the world leader in mobile near-field communication (NFC), ...      (Logo: http://photos.prnewswire.com/prnh/20140612/691055) , ...
Breaking Biology News(10 mins):New telemetry implants expected to change how large animal toxicology studies are conducted 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 2Jifflenow And ITN International Bring Cutting-Edge Badge Scanning Technology To B2B Events 3
... are old. Really old, in fact, which comes as a ... tree growth in the world's largest tropical region. , Using ... Trumbore, found that up to half of all trees greater ... old. Some of the trees, Trumbore said, are as much ...
... National Human Genome Research Institute (NHGRI), both part ... launched a comprehensive effort to accelerate our understanding ... application of genome analysis technologies, especially large-scale genome ... Atlas (TCGA), will begin with a pilot project ...
... University of Pennsylvania School of Medicine have discovered that ... (pre-mRNA), a process once believed to only take place ... capability in dendrites, the investigators hope to relate this ... dysfunction. Senior author James Eberwine, PhD, Professor of Pharmacology, ...
Cached Biology News:Amazon trees much older than assumed, raising questions on global climate impact of region 2NIH launches comprehensive effort to explore cancer genomics 2NIH launches comprehensive effort to explore cancer genomics 3NIH launches comprehensive effort to explore cancer genomics 4RNA splicing occurs in nerve-cell dendrites 2RNA splicing occurs in nerve-cell dendrites 3
(Date:12/19/2014)... Dec. 19, 2014 Research and Markets ... of the "Technology Innovations in Smart Fabrics ... http://photos.prnewswire.com/prnh/20130307/600769 ... Fabrics" offers a detailed assessment on technological advancements ... Findings: 1. The Smart Fabrics ...
(Date:12/19/2014)... MA (PRWEB) December 18, 2014 LayerBio ... for ophthalmology and wound care. The National Eye Institute ... awarded LayerBio a Phase I SBIR grant to develop ... Cataracts are the most common cause of vision loss ... of blindness worldwide. According to Dr. Ken Mandell, LayerBio’s ...
(Date:12/19/2014)... (PRWEB) December 18, 2014 iLab Solutions, ... the appointment of Siri Bryant as the new Director ... Director of Core Implementations. These two new leadership positions ... customer service by ensuring that iLab continues to meet ... the last four years, iLab has been deployed at ...
(Date:12/19/2014)... (PRWEB) December 18, 2014 With only ... time special on Sartorius Biohit products . The ... mLINE pipettes, Picus Electronic Pipette Trade-in Program, and free ... and Safety officers around the world. They are ideal ... Other features include:, ,     Full volume range ...
Breaking Biology Technology:Technology Innovations in Smart Fabrics (Technical Insights) 2LayerBio Awarded NIH Grant to Develop a Drug Delivery Device for Cataract Surgery 2iLab Solutions Announces Two New Leadership Positions to Meet the Needs of Its Growing Customer Base 2Major Pipette Distributor Pipette.com Announces Sartorius Year End Specials 2
... Sangamo BioSciences, Inc. (Nasdaq: SGMO ) today ... financial results on Tuesday, October 25, 2011, after the market ... call at 5:00 p.m. ET, which will be open to ... the company will review the financial results and discuss other ...
... Mass., Oct. 18, 2011 The Outercurve Foundation ... project into the Research Accelerators Gallery. .Net Bio, ... supports the development of applications for bioinformatics research, ... The open source project, which has the support ...
... Invasive Devices, Inc . (MID) announced today the early market ... the novel Flo-X laparoscopic cleaning agent, which allows for active ... removal from the abdominal cavity. Flo-X is the ... first 19 FloShield PLUS cases utilizing the Flo-X, any required ...
Cached Biology Technology:Sangamo BioSciences Announces Third Quarter 2011 Conference Call and Webcast 2Outercurve Foundation Announces Contribution of .Net Bio Project 2
HSD17B3 Immunogen: HSD17B3 (NP_000188, 29 a.a. ~ 120 a.a) partial recombinant protein with GST tag. Storage: -20 C, Avoid Freeze/Thaw Cycles *Available for distribution in the US only...
Rad51, N-terminal...
Phospho-mu-Opioid Receptor (Ser375) Antibody...
Rabbit polyclonal to WWOX8 ( Abpromise for all tested applications). entrezGeneID: 51741 SwissProtID: Q9NZC7-8...
Biology Products: