Navigation Links
Vaccine-producing 'plant-factories'

A research team at the Consejo Superior de Investigaciones Científicas (CSIC) has discovered a new route for the transport of proteins in plant cells, a discovery that will enable the biotechnological design of plant factories. Amongst other applications, these can be used to produce oral vaccines which, upon being ingested, will be able to immunise against diseases. Moreover, this discovery opens the door to the design of protein-manufacturing plants of great interest therapeutically and in the development of vaccine antigens.

This discovery, published in the latest issue of The Plant Cell, contributes, moreover, to refuting one of the current scientific dogmas regarding the mechanisms of protein transportation in plant cells.

The research was carried out by a team from the Institute of Agrobiotechnology and Natural Resources (a centre jointly run by the CSIC, the Public University of Navarre and the Government of Navarre), made up of Javier Pozueta, Francisco José Muñoz and Edurne Baroja. These scientists have been aided by a research team from Niigata University (Japan).

Specifically, the study describes a new route for the traffic of proteins from the reticular/Golgi system where there are glycosylates, towards the chloroplasts of the plant cell. Some of these glycosylated recombinant proteins have significant antigenic power of great pharmaceutical interest.

Conventional biotechnological methods enable the cells to accumulate very limited quantities of glycosylate recombinant proteins. The chloroplast is a cell organ with great capacity for storing proteins. However, it is incapable of producing glycosylate proteins.

The newly discovered route connects the cell organ where the proteins are glycosylated, the reticulum, with the chloroplasts. This discovery signifies the first step in the development of plants and algae that accumulate in their chloroplasts large amounts of glycosylate recombinant proteins with sig
'"/>

Source:Elhuyar Fundazioa


Page: 1 2

Related biology news :

1. Newly discovered virus linked to childhood lung disorders and Kawasaki disease
2. Low level of extinction during ice age linked to adaptability
3. Improved statistical tools reveal many linked loci
4. Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
5. Attacks of King George IIIs madness linked to key metabolism molecule
6. Gene controlling circadian rhythms linked to drug addiction
7. Physical and functional interaction of key cell growth molecules linked to cancer
8. VCU Massey Cancer Center study shows enzyme linked to spread of breast cancer cells
9. Naturally occurring asbestos linked to lung cancer
10. Disappearing arctic lakes linked to climate change
11. Genes linked to treatment resistance in children with leukemia
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Vaccine producing plant factories

(Date:6/18/2013)... extract of a yellow-flowered mountain plant long used for ... fruit fly populations by an average of 24 percent, ... Rhodiola rosea , also known as ... study leaders Mahtab Jafari and Sam Schriner. They discovered ... unrelated to dietary restriction and affects different molecular pathways. ...
(Date:6/18/2013)... of Adelaide shows that weight gain and increased head size ... a higher IQ at early school age. , The study was ... from more than 13,800 children who were born full-term. , The ... that babies who put on 40% of their birthweight in the ... time they were six years of age, compared with babies who ...
(Date:6/17/2013)... LA JOLLA, CA June 17, 2013 An ... Institute (TSRI), the Howard Hughes Medical Institute and Albert ... a highly promising new anti-tuberculosis compound that attacks the ... findings represent an effort to help solve one of ... of TB and its dangerous drug-resistant strains," said Peter ...
Breaking Biology News(10 mins):Herbal extract boosts fruit fly lifespan by nearly 25 percent, UCI study finds 2IQ link to baby's weight gain in first month 2New compound excels at killing persistent and drug-resistant tuberculosis 2New compound excels at killing persistent and drug-resistant tuberculosis 3New compound excels at killing persistent and drug-resistant tuberculosis 4
... common cause of pain and disability and ... and hip fractures. Yet there is evidence that ... fractures in their patients. Even if the fractures ... The Vertebral Fracture Initiative, available at ...
... 9, 2011 MaxID Pty Ltd, a wholly owned company ... is pleased to announce that it has won a 1000-unit ... "MaxID, with its distribution partner, Pinnacle Technology Holdings Ltd Group, ... Africa market.  Our iDL500, which is an incredibly proven device ...
... researchers have designed a new tool for identifying protein ... Ekker, Ph.D., succeeded in switching individual genes off and ... The study appears in the journal Nature Methods ... health-related problems such as how cancerous cells spread, what ...
Cached Biology News:New IOF teaching tool helps health professionals identify vertebral fractures 2MaxID Lands Sale of 1000 iDL500 Multi-Modal Handheld Identity Devices in South Africa 2In a genetic research first, Mayo Clinic turns zebrafish genes off and on 2In a genetic research first, Mayo Clinic turns zebrafish genes off and on 3
(Date:6/18/2013)... As a leading provider of telehealth ... release of their infographic - " 8 New ... goal was to leverage an information graphic to ... 3.0 and mHealth.The infographic features a list of ... the fitness industry in unimaginable ways; turning science ...
(Date:6/18/2013)... PathoGenetix, Inc. , a commercial-stage ... strain typing, announced today that John A. Luckey, ... President of Engineering. Dr. Luckey will lead technology ... Microbial Genotyping System . The fully automated RESOLUTION ... kits, database and software, will be commercially available ...
(Date:6/18/2013)... (PRWEB) June 18, 2013 Kitware ... today announces a new Fast-Track award from the U.S. ... design-analysis environment (IDAE) for the nuclear power industry. , ... for more than 30 years, but the United States’ ... remarkable gains in power plant utilization through improved refueling, ...
(Date:6/17/2013)... zuChem Inc., a leading producer of ... today that the United States Patent and Trademark ... 8,367,346 entitled “Methods for Production of Xylitol in ... D-Mannitol." These two patents expand zuChem's technology portfolio ... products from abundant, renewable feedstocks. , The ...
Breaking Biology Technology:MeMD, Inc Releases Infographic Featuring the Top Eight Technologies that are Revolutionizing Health and Fitness Today 2PathoGenetix Hires Technology Development VP for Resolution Microbial Genotyping System 2PathoGenetix Hires Technology Development VP for Resolution Microbial Genotyping System 3Kitware to Develop an Open-Source HPC Design-Analysis Environment for Nuclear Energy Research 2zuChem Receives Two Polyol Patents 2
... W.Va. Recent studies conducted at Marshall University have demonstrated ... used to increase the fuel efficiency of automobile engines -- ... this process is associated with liver damage. The ... his colleagues at Marshall,s Center for Diagnostic Nanosystems indicate there ...
... Nov. 17, 2011 Today BioSpace , the ... 2011-2012 BioForest™ Hotbed Campaign , marking the 7th ... The campaign highlights leading organizations across the ... is added to an electronic and printed campaign ...
... Builders, an award-winning general contractor specializing in a wide ... selected by the Los Angeles Biomedical Research Institute at ... of the initial phase for the creation of a ... 72-acre Harbor-UCLA Medical Center in Torrance, California.  Webcor will ...
Cached Biology Technology:Marshall study shows nanoparticles used as additives in diesel fuels can travel from lungs to liver 2BioSpace Spotlights Northwest's Life Science Community 2Webcor Builders Selected as the General Contractor for First Phase of LA BioMed's New Campus Master Plan 2Webcor Builders Selected as the General Contractor for First Phase of LA BioMed's New Campus Master Plan 3
15(S)-HETE-d8 is used as an internal standard for the quantification of 15(S)-HETE by stable isotope dilution mass spectrometry....
...
...
All-in-one mix, removes primers and dNTPs from PCR product for following direct sequencing...
Biology Products: