Navigation Links
Vaccine-producing 'plant-factories'

A research team at the Consejo Superior de Investigaciones Científicas (CSIC) has discovered a new route for the transport of proteins in plant cells, a discovery that will enable the biotechnological design of plant factories. Amongst other applications, these can be used to produce oral vaccines which, upon being ingested, will be able to immunise against diseases. Moreover, this discovery opens the door to the design of protein-manufacturing plants of great interest therapeutically and in the development of vaccine antigens.

This discovery, published in the latest issue of The Plant Cell, contributes, moreover, to refuting one of the current scientific dogmas regarding the mechanisms of protein transportation in plant cells.

The research was carried out by a team from the Institute of Agrobiotechnology and Natural Resources (a centre jointly run by the CSIC, the Public University of Navarre and the Government of Navarre), made up of Javier Pozueta, Francisco José Muñoz and Edurne Baroja. These scientists have been aided by a research team from Niigata University (Japan).

Specifically, the study describes a new route for the traffic of proteins from the reticular/Golgi system where there are glycosylates, towards the chloroplasts of the plant cell. Some of these glycosylated recombinant proteins have significant antigenic power of great pharmaceutical interest.

Conventional biotechnological methods enable the cells to accumulate very limited quantities of glycosylate recombinant proteins. The chloroplast is a cell organ with great capacity for storing proteins. However, it is incapable of producing glycosylate proteins.

The newly discovered route connects the cell organ where the proteins are glycosylated, the reticulum, with the chloroplasts. This discovery signifies the first step in the development of plants and algae that accumulate in their chloroplasts large amounts of glycosylate recombinant proteins with sig
'"/>

Source:Elhuyar Fundazioa


Page: 1 2

Related biology news :

1. Newly discovered virus linked to childhood lung disorders and Kawasaki disease
2. Low level of extinction during ice age linked to adaptability
3. Improved statistical tools reveal many linked loci
4. Scientists at Galileo Pharmaceuticals confirm inflammatory response linked to glucose levels
5. Attacks of King George IIIs madness linked to key metabolism molecule
6. Gene controlling circadian rhythms linked to drug addiction
7. Physical and functional interaction of key cell growth molecules linked to cancer
8. VCU Massey Cancer Center study shows enzyme linked to spread of breast cancer cells
9. Naturally occurring asbestos linked to lung cancer
10. Disappearing arctic lakes linked to climate change
11. Genes linked to treatment resistance in children with leukemia
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Vaccine producing plant factories

(Date:9/23/2014)... immediate welfare consequences of removing infant chimpanzees from their ... long-term impacts of this type of early life experience. ... observed 60 chimpanzees and concluded that those who were ... by humans as pets or performers are likely to ... multi-institutional research project, published today in the open-access journal ...
(Date:9/22/2014)... Many native species have vanished from tropical islands ... scientists have discovered how fossils can be used ... lies in organic materials found in fossil bones, ... according to a new study available online and ... of Herpetology . Pre-human island ecosystems provide vital ...
(Date:9/22/2014)... 22, 2014Cassava, also known as tapioca, has large starch-filled ... of Africa, Asia, and Latin America where corn and ... novel enzymes and processes designed to break down tapioca ... produce sweeteners such as glucose, fructose, or maltose syrup, ... described in a Review article in Industrial Biotechnology ...
Breaking Biology News(10 mins):Chimpanzees raised as pets or performers suffer long-term effects on their behavior 2Answer to restoring lost island biodiversity found in fossils 2
... a protein channel helps nerve sensors in blood vessels keep ... ASIC2, the sensors are unable to send the brain the ... finding, which was based in animal models, is important because ... high blood pressure (hypertension). The study results appear in the ...
... marine turtles around the world,s oceans will be available to ... launched by the University of Exeter. Noelle and ... Gabon, Western Central Africa. The research team has fitted each ... scientists to monitor their precise movements and observe where and ...
... one of its international professorships to John Leslie, professor ... State University. The society has awarded Leslie an ... visiting professor at the Universidad Nacional de Rio Cuarto ... Workshop in March 2010. The workshop helps participants ...
Cached Biology News:Study shows a key protein helps control blood pressure 2Study shows a key protein helps control blood pressure 3Turtles' Christmas journey tracked by scientists 2
(Date:9/23/2014)... Calif. , Sept. 23, 2014 ... in India devoted to genome-based research ... Biomedical Genomics (NIBMG) is taking a bite out of ... cancer among males in India with ... storage solutions from DataDirect Networks (DDN). , To fuel ...
(Date:9/23/2014)... New York , September 23, 2014 /PRNewswire/ ... a leading provider of  Closed System Transfer     ... new exclusive partnership with Taiwanese distributor MedFront Medical Technology Corporation. ... bodies in Taiwan , ... approval as the company continues to expand globally, ...
(Date:9/23/2014)... MN (PRWEB) September 23, 2014 ... NimbeLink, a developer of cellular modems , ... finalist in the Startup category for the 2014 ... be held at the Minneapolis Convention Center on ... companies and individuals who have shown superior technology ...
(Date:9/22/2014)... Research and Markets ( ... "Global Biotechnology Reagents Market 2014-2018" report ... Biotechnology reagents are chemical compounds or ... detect and examine another substance to provide a ... to prepare, collect, and examine specimens from the ...
Breaking Biology Technology:National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 2National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 3National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 4National Institute of Biomedical Genomics (NIBMG) Deploys DataDirect Networks Storage to Achieve Significant Performance Improvement in World-Class Genomics Research and Collaboration for Oral Cancer 5Equashield Enters Taiwan Following Expansion to Australia, Japan, China 2NimbeLink Named Finalist for 15th Annual Tekne Awards 2NimbeLink Named Finalist for 15th Annual Tekne Awards 3Global Biotechnology Reagents Market 2014-2018: Key Vendors are Agilent, BD Biosciences, Bio-Rad, F. Hoffmann-La Roche, Sigma-Aldrich and Thermo Fisher 2Global Biotechnology Reagents Market 2014-2018: Key Vendors are Agilent, BD Biosciences, Bio-Rad, F. Hoffmann-La Roche, Sigma-Aldrich and Thermo Fisher 3
... BRISBANE, Australia and SEATTLE, Feb. 24 Implicit,Bioscience ... antibody IC14 from Eli Lilly and Company. Implicit ... to Lilly. Lilly will also,receive a royalty on ... "Implicit Bioscience brings substantial expertise and passion to ...
... Feb. 24 Nektar Therapeutics,(Nasdaq: NKTR ... fourth quarter and,year ended December 31, 2008. , ... year for Nektar," said Howard W. Robin,President and ... unique polymer,conjugation chemistry platform, we advanced numerous proprietary ...
... proteinTHOUSAND OAKS, Calif., Feb. 24 Bone Biologics, Inc. ... Aragen Bioscience, has completed development of a recombinant cell ... protein. Bone Biologics has been developing the protein as ... years of research in the lab performed by the ...
Cached Biology Technology:Implicit Licenses Clinical Stage Antibody Program From Lilly 2Implicit Licenses Clinical Stage Antibody Program From Lilly 3Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 2Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 3Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 4Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 5Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 6Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 7Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 8Nektar Therapeutics Reports Fourth Quarter and Year-End 2008 Financial Results 9Bone Biologics Announces UCB-1 (NELL-1) Bone Growth Protein Production Process With Aragen Biosciences 2
... is a new product number, created to ... no availability yet, please order under the ... service for assistance. ID clarifier: ... area 500 cm 2 D ...
BD BioCoat Collagen IV 150 mm Culture Dishes...
...
...
Biology Products: