Navigation Links
Updated data on novel HPV vaccine confirms efficacy in large population

Updated data from a study on a promising new vaccine against a pre-cancerous cervical virus shows superior efficacy in preventing cervical pre-cancers and non-invasive cervical cancer, according to a study presented today during the American Association for Cancer Research's 4th Annual Frontiers in Cancer Prevention Research meeting in Baltimore.

Final results of the phase III study, originally published in early October, confirmed the vaccine's efficacy from available combined phase II and phase III data sets, incorporating an additional 7,000 patient records as compared to the interim results. The researchers concluded from these analyses that the administration of this vaccine, known as GARDASIL, is highly effective in preventing high-grade pre-cancerous illnesses and non-invasive cervical cancers.

Of the 8,487 women who received the vaccine, none were diagnosed with high-grade cervical pre-cancers (CIN 2/3+, cervical intraepithelial neoplasia) or non-invasive cervical cancers associated with human papillomavirus (HPV) types 16 and 18. Of the 8,460 women who did not receive the vaccine, 53 such cases were diagnosed.

In the larger population analysis, which included women who may have become infected with HPV during the vaccination period or who may have violated the protocol (e.g. by missing visits, etc.), the vaccine prevented 99 percent of HPV 16 or 18-related high-grade cervical pre-cancers (1 of 9,342 pts versus 81 of 9,400 in the placebo group) with an average follow up of 25 months.

The vaccine was generally well tolerated, and the most common adverse event reported in the trial was local discomfort at the injection site.

The study is part of an ongoing phase III program involving more than 25,000 people in 33 countries. For the FUTURE II study, a prospective, randomized, double-blind, placebo-controlled study, women aged 16 to 26 years were randomized to receive a three-dose regimen of either the vaccine
'"/>

Source:American Association for Cancer Research


Page: 1 2

Related biology news :

1. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
2. Insight into natural cholesterol control suggests novel cholesterol-lowering therapy
3. GeneNotes - A novel information management software for biologists
4. Endocannabinoids ?the brains cannabis ?demonstrate novel modes of action to stress
5. A novel virus for croup
6. Scientists show that tick-borne flaviviruses use a novel mechanism to evade host defenses
7. A novel method to measure circadian cycles
8. UCSD discovery may provide novel method to generate medically useful proteins
9. Neurons generated in the adult brain learn to respond to novel stimuli
10. Federal grant funds research on novel HIV therapy
11. Mutations in the BRAF gene predict sensitivity to a novel class of cancer drugs
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Updated data novel HPV vaccine confirms efficacy large population

(Date:9/19/2014)... that legume plants regulate their symbiotic relationship with ... transmitted through the plant structure from leaves into ... nodules in the roots. This collaborative study was ... Basic Biology, the Graduate University for Advanced Studies ... Science in Japan. , Legumes, an important ...
(Date:9/18/2014)... A sleep-promoting circuit located deep in the primitive brainstem ... by researchers at Harvard School of Medicine and the ... this is only the second "sleep node" identified in ... necessary and sufficient to produce deep sleep. , Published ... study demonstrates that fully half of all of the ...
(Date:9/18/2014)... Mass. A novel robotic system that can operate ... being tested as part of a biomedical research partnership ... the aim of determining if the robot, in conjunction ... faster, more accurate, less costly, and less discomforting for ... to deliver prostate cancer therapies with greater precision. , ...
Breaking Biology News(10 mins):For legume plants, a new route from shoot to root 2No sedative necessary: Scientists discover new 'sleep node' in the brain 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 2Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 3Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 4Trial begins for MRI-compatible robot designed to improve accuracy of prostate biopsies 5
... NOAA scientists have found that pressure from increasing ... and climate change are critically threatening the health of ... such as green sea turtles and coral habitat continue ... The findings were released today in the ...
... which yawns wide every Southern Hemisphere spring, reached its ... million square miles, the ninth largest ozone hole on ... its deepest point of the season on Oct. 9, ... 26-year record. NASA and the National Oceanic and ...
... largest DNA data sets for a group of birds ... have determined the evolutionary family tree for one of ... the world, the Hawaiian honeycreepers. Not only ... the honeycreeper family originally evolved from, but they have ...
Cached Biology News:NOAA releases status on Florida Keys National Marine Sanctuary marine resources 2NASA, NOAA data show significant Antarctic ozone hole remains 2NASA, NOAA data show significant Antarctic ozone hole remains 3Scientists determine family tree for most-endangered bird family in the world 2Scientists determine family tree for most-endangered bird family in the world 3
(Date:9/22/2014)... METTLER TOLEDO is pleased to launch ... CNS110 ScanTape™ . Replacing a traditional tape ... ease and accuracy for transport and logistics personnel. ... productivity—an important benefit for load planning and revenue ... , Usable at any point in goods-transfer ...
(Date:9/21/2014)... time, scientists have discovered how to produce ultra-thin "diamond ... greater than that of today,s strongest nanotubes and polymers. ... led by John V. Badding, a professor of chemistry ... 21 September 2014 issue of the journal Nature ... our discovery is intriguing because the threads we formed ...
(Date:9/20/2014)... (PRWEB) September 20, 2014 MediVet ... to perform a groundbreaking surgery at the specialized Wolvega ... mare's superficial digital flexor tendon was ruptured 90% and ... of injury is a death sentence for a horse. ... stem cell treatments . This revolutionary regenerative ...
(Date:9/19/2014)... Chips that use light, rather than electricity, to ... and energy efficiency is a growing concern as ... chief components of optical circuits light emitters, ... to build. One promising light source for optical ... optical properties when deposited as a single, atom-thick ...
Breaking Biology Technology:ScanTape™ Handheld Dimensioner Increases Processing Volume 2Smallest possible diamonds form ultra-thin nanothreads 2Smallest possible diamonds form ultra-thin nanothreads 3Smallest possible diamonds form ultra-thin nanothreads 4World’s first tendon replacement using Nanofiber and activated MediVet Stem Cell Fraction 2World’s first tendon replacement using Nanofiber and activated MediVet Stem Cell Fraction 3Toward optical chips 2Toward optical chips 3
... Barr III, 65, is retiring as president and CEO of the ... role, the company said on Tuesday. , ,Barr's replacement is already ... local telecommunications operations, has been named chief operating officer and will ... has been with the company for two decades and was involved ...
... MPower Technologies , a local software and consulting firm, ... to make a new geographic information systems application, the ... allows organizations to create and distribute land records data ... understand the challenges faced by organizations trying to maintain ...
... sit writing this article, we are 42 days away from the ... to thinking, "But wait, isn't this meeting normally in June?", you ... held in June, but not this year. , ,The BIO ... meeting about 2 months earlier than normal for a couple of ...
Cached Biology Technology:42 days until the 2006 Olympics of Biotechnology in Chicago 242 days until the 2006 Olympics of Biotechnology in Chicago 342 days until the 2006 Olympics of Biotechnology in Chicago 442 days until the 2006 Olympics of Biotechnology in Chicago 5
Adjustable tilt angle 0 to 20 Adjustable speed of 3-25 RPM Load capacity: 2.7 kg (6 lbs.) Ambient temperature range 4C to 65C Low voltage power is supplied by wall mount transformer...
...
Request Info...
Request Info...
Biology Products: