Navigation Links
Unraveling where chimp and human brains diverge

Six million years ago, chimpanzees and humans diverged from a common ancestor and evolved into unique species. Now UCLA scientists have identified a new way to pinpoint the genes that separate us from our closest living relative ?and make us uniquely human. The Proceedings of the National Academy of Sciences reports the study in its Nov. 13 online edition.

"We share more than 95 percent of our genetic blueprint with chimps," explained Dr. Daniel Geschwind, principal investigator and Gordon and Virginia MacDonald Distinguished Professor of Human Genetics at the David Geffen School of Medicine. "What sets us apart from chimps are our brains: homo sapiens means 'the knowing man.'

"During evolution, changes in some genes altered how the human brain functions," he added. "Our research has identified an entirely new way to identify those genes in the small portion of our DNA that differs from the chimpanzee's."

By evaluating the correlated activity of thousands of genes, the UCLA team identified not just individual genes, but entire networks of interconnected genes whose expression patterns within the brains of humans varied from those in the chimpanzee.

"Genes don't operate in isolation ?each functions within a system of related genes," said first author Michael Oldham, UCLA genetics researcher. "If we examined each gene individually, it would be similar to reading every fifth word in a paragraph ?you don't get to see how each word relates to the other. So instead we used a systems biology approach to study each gene within its context."

The scientists identified networks of genes that correspond to specific brain regions. When they compared these networks between humans and chimps, they found that the gene networks differed the most widely in the cerebral cortex -- the brain's most highly evolved region, which is three times larger in humans than chimps.

Secondly, the researchers discovered that many
'"/>

Source:University of California - Los Angeles


Page: 1 2

Related biology news :

1. Unraveling a stomach cancer puzzle
2. Unraveling the mysteries of poison
3. Unraveling the viral mechanism
4. Discovery of an American salamander where it shouldnt be: Korea
5. Vaccine targets tumors where they live
6. Telling axons where to go - and grow
7. Plant studies reveal how, where seeds store iron
8. Plant studies reveal how, where seeds store iron
9. Why do oysters choose to live where they could be eaten?
10. The death of a very special chimpanzee
11. Retrovirus struck ancestors of chimpanzees and gorillas millions of years ago, but did not affect ancestral humans
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Unraveling where chimp and human brains diverge

(Date:4/14/2015)... Conn. , April 14, 2015 NXT-ID, ... a biometric authentication company focused on the growing mobile ... been nominated for the 2015 New York Design Awards ... The Design100, New York City Design Awards are part ... based on over 2,500 ratings from the marketplace, industry ...
(Date:4/9/2015)... , April 9, 2015 Synaptics Inc. (NASDAQ: ... solutions, announced today that it will report financial results ... April 23, 2015, after the close of market. The ... and investors at 2:00 p.m. PT (5:00 p.m. ET), ... To participate on the live call, analysts and ...
(Date:4/2/2015)... , April 2, 2015 At its 2015 ... Lake City , the American College of Medical ... new directors to its Board.  Members of the ACMG ... and for forming and advancing its policies and programs. ... profession. "It,s an eventful time in medical ...
Breaking Biology News(10 mins):NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 2NXT-ID's Wocket Smart Wallet Nominated for 2015 New York Design Awards in 'Product Design- Technology' 3Synaptics to Report Third Quarter Results on April 23 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 2American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 3American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 4American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 5American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 6American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 7American College of Medical Genetics and Genomics Announces New Board Members: Dr. Louanne Hudgins is ACMG President-Elect 8
... Colo., USA - The February 2014 Lithosphere ... travertine in the Rio Grande rift, central New Mexico; ... Australia; the first lithosphere-scale illustration of the structural evolution ... formation; evaluation of the central Garlock fault in Pilot ...
... David Allis, a pioneer in the field of epigenetics whose ... role in regulating the activity of individual genes, will be ... by the Japan Prize Foundation, was made at a press ... approximately half a million dollars, is among the most prestigious ...
... Institute,s Illinois Natural History Survey have found that overall, concentrations ... from the lower Illinois River do not appear to be ... The full results of the study have been published in ... mercury concentration in fillets was below the US Food and ...
Cached Biology News:Rio Grande fift, Rum Jungle complex, Black Sea, West Africa craton, California faults 2Rio Grande fift, Rum Jungle complex, Black Sea, West Africa craton, California faults 3Rio Grande fift, Rum Jungle complex, Black Sea, West Africa craton, California faults 4Rio Grande fift, Rum Jungle complex, Black Sea, West Africa craton, California faults 5David Allis, pioneer in epigenetics, to receive prestigious Japan Prize 2Research shows arsenic, mercury and selenium in Asian carp not a health concern to most 2
(Date:4/30/2015)... 30, 2015  The Paul G. Allen Family Foundation ... grants to six groups of researchers with projects at ... in neuroscience: growing mature human brain cells in the ... $7.5 million over three years.  "This ... is especially significant because the field of neuronal maturation ...
(Date:4/30/2015)... WuXi PharmaTech (Cayman) Inc. ("WuXi" or the ... R&D services provider, today announced that its board of ... April 29, 2015, from a consortium (the "Consortium") led ... chairman and chief executive officer of the Company, and ... transaction (the "Transaction") involving the acquisition of all outstanding ...
(Date:4/30/2015)... Clinovo Staffing Solutions will represent Clinovo ... in Orlando, FL on May 17-20th, 2015. Trisha Heredia, ... Manager of Staffing Solutions, will present Clinovo’s staffing services ... , “We are excited to be participating in ... Heredia, Senior Director of Staffing Solutions at Clinovo. “PharmaSUG ...
(Date:4/29/2015)... GUELPH, ON , April 29, 2015 /PRNewswire/ - BIOREM Inc. (TSX-V: BRM) ... twelve-month periods ended December 31, 2014. Biorem,s complete fiscal 2014 year-end financial ... FINANCIAL HIGHLIGHTS: 2014 , 2013 , 2014 ... 10,683 , 19,596 Gross profit 1,326 , ... 1,191 , 1,493 , 3,377 , ...
Breaking Biology Technology:The Paul G. Allen Family Foundation Awards $7.5 Million To Study Brain Cell Growth And Development 2The Paul G. Allen Family Foundation Awards $7.5 Million To Study Brain Cell Growth And Development 3The Paul G. Allen Family Foundation Awards $7.5 Million To Study Brain Cell Growth And Development 4The Paul G. Allen Family Foundation Awards $7.5 Million To Study Brain Cell Growth And Development 5WuXi PharmaTech Announces Receipt of Proposal 2WuXi PharmaTech Announces Receipt of Proposal 3WuXi PharmaTech Announces Receipt of Proposal 4WuXi PharmaTech Announces Receipt of Proposal 5WuXi PharmaTech Announces Receipt of Proposal 6Clinovo Exhibits at the 2015 PharmaSUG Annual Conference on May 17-20th in Orlando, FL 2Clinovo Exhibits at the 2015 PharmaSUG Annual Conference on May 17-20th in Orlando, FL 3Biorem Reports Results for Fourth Quarter 2014 and Year Ended December 31, 2014 2Biorem Reports Results for Fourth Quarter 2014 and Year Ended December 31, 2014 3Biorem Reports Results for Fourth Quarter 2014 and Year Ended December 31, 2014 4
... help manufactures manage some of the most complex, ... the world. The company will now offer Boston-based ... save millions of dollars with improved supply chain ... customers who choose to optimize inventories and improve ...
... differential between U.S. white collar workers and those in India ... , ,IT Manager ,U.S: $55,000 ,India: $8,500 , ,Accountant ,U.S.: ... United States were almost solely in the manufacturing sector, as ... or other Latin American countries to cut costs. Not to ...
... like something from a futuristic movie. But Plexus, ... Neenah, Wis., is making those futuristic dreams a ... manufacturer of fingerprint sensors. , ,Plexus announced the ... integration services for AuthenTec's TruePrint technology-based fingerprint sensors. ...
Cached Biology Technology:Schneider Logistics Helps Manufacturers Secure Competitive Advantage 2Outsourcing Offshore - Wisconsin Companies Sending Work Abroad 2Outsourcing Offshore - Wisconsin Companies Sending Work Abroad 3Plexus Partnering with AuthenTec 2
...
... Mouse monoclonal [RS17 ] to PRKAR2 ... a variety of cellular functions. cAMP exerts ... kinase (AMPK), which transduces the signal through ... holoenzyme of AMPK is a tetramer composed ...
...
... a Perkin Elmer UltraVIEW system and want to ... and iQ software? No problem. Our experienced ... your existing microscope, lasers, Sutter filter wheel, Piezo ... work with our precision controller unit and workstation... ...
Biology Products: