Navigation Links
Unraveling where chimp and human brains diverge

Six million years ago, chimpanzees and humans diverged from a common ancestor and evolved into unique species. Now UCLA scientists have identified a new way to pinpoint the genes that separate us from our closest living relative ?and make us uniquely human. The Proceedings of the National Academy of Sciences reports the study in its Nov. 13 online edition.

"We share more than 95 percent of our genetic blueprint with chimps," explained Dr. Daniel Geschwind, principal investigator and Gordon and Virginia MacDonald Distinguished Professor of Human Genetics at the David Geffen School of Medicine. "What sets us apart from chimps are our brains: homo sapiens means 'the knowing man.'

"During evolution, changes in some genes altered how the human brain functions," he added. "Our research has identified an entirely new way to identify those genes in the small portion of our DNA that differs from the chimpanzee's."

By evaluating the correlated activity of thousands of genes, the UCLA team identified not just individual genes, but entire networks of interconnected genes whose expression patterns within the brains of humans varied from those in the chimpanzee.

"Genes don't operate in isolation ?each functions within a system of related genes," said first author Michael Oldham, UCLA genetics researcher. "If we examined each gene individually, it would be similar to reading every fifth word in a paragraph ?you don't get to see how each word relates to the other. So instead we used a systems biology approach to study each gene within its context."

The scientists identified networks of genes that correspond to specific brain regions. When they compared these networks between humans and chimps, they found that the gene networks differed the most widely in the cerebral cortex -- the brain's most highly evolved region, which is three times larger in humans than chimps.

Secondly, the researchers discovered that many
'"/>

Source:University of California - Los Angeles


Page: 1 2

Related biology news :

1. Unraveling a stomach cancer puzzle
2. Unraveling the mysteries of poison
3. Unraveling the viral mechanism
4. Discovery of an American salamander where it shouldnt be: Korea
5. Vaccine targets tumors where they live
6. Telling axons where to go - and grow
7. Plant studies reveal how, where seeds store iron
8. Plant studies reveal how, where seeds store iron
9. Why do oysters choose to live where they could be eaten?
10. The death of a very special chimpanzee
11. Retrovirus struck ancestors of chimpanzees and gorillas millions of years ago, but did not affect ancestral humans
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Unraveling where chimp and human brains diverge

(Date:4/17/2014)... NY, April 17, 2014The development of stem cell therapies ... ability to characterize stem cell populations based on cell ... discovered a new marker that is highly expressed in ... cord blood, which they describe in an article in ... Mary Ann Liebert, Inc., publishers. The article is available ...
(Date:4/17/2014)... births, Down syndrome - or trisomy 21 - is ... results from a chromosomal abnormality where cells of affected ... of the human genome). A study conducted by Stylianos ... Medicine and Development at the University of Geneva (UNIGE) ... light on how the extra chromosome 21 upsets the ...
(Date:4/17/2014)... White House honored Clemson professor Rajendra Singh Thursday ... to promote and expand solar deployment in the ... D. Houser Banks Professor of Electrical and Computer ... Nanoelectronics, is considered a local hero leading the ... economic opportunity in solar power and driving policy ...
Breaking Biology News(10 mins):Trisomy 21: How an extra little chromosome throws the entire genome off balance 2Trisomy 21: How an extra little chromosome throws the entire genome off balance 3White House honors Clemson professor as 'Champion of Change' for solar deployment 2
... orchids are found in habitats where light may be ... surprising that many achlorophyllous (lacking chlorophyll), as well as ... supply them with carbohydrates in order to grow. However, ... and range in their photosynthetic capabilities. For those ...
... 07/07/11, Clearwater Beach, FL. Research to be presented ... Study of Ingestive Behavior (SSIB), the foremost society for research ... ghrelin, a naturally occurring gut hormone, increases our willingness to ... for non-food items. Have you ever wondered about why ...
... developing limbs and digits were present in primitive fish ... to land, researchers have discovered. Genetic switches control ... particular switch taken from fish DNA is placed into ... developing limb region of embryos, University of Chicago researchers ...
Cached Biology News:Orchids and fungi: An unexpected case of symbiosis 2Orchids and fungi: An unexpected case of symbiosis 3Orchids and fungi: An unexpected case of symbiosis 4Genetic switch for limbs and digits found in ancient fish 2Genetic switch for limbs and digits found in ancient fish 3
(Date:1/14/2014)... (PRWEB) January 14, 2014 Carahsoft and ... Thursday, January 23, 2014 at 2pm EST (11am PST), ... The topic focuses on how technology can turn raw, ... decisions for government agencies. The online webinar will last ...
(Date:1/14/2014)... NY (PRWEB) January 14, 2014 EquitiesIQ, ... Alliqua, Inc. (OTCQB: ALQA). Alliqua is an emerging biomedical ... serve the wound care market. , Free report download: ... restructured with a seasoned management team and Board, which ...
(Date:1/14/2014)... 2014 In recent years, growing suspicion ... in product development and promotion has led to unprecedented ... fueled by concerns about the insidious impact of commercialization ... spectacular fines to the world’s biggest pharmas for illegal ...
(Date:1/14/2014)... (PRWEB) January 13, 2014 Bob Hainsey, ... more than 20 years in the industry, has joined ... . Hainsey will serve as the society’s Science and ... Hainsey join SPIE as our Technology Strategist, further strengthening ...
Breaking Biology Technology:Webcast - Natural Language Processing: Converting Raw Data into Actionable Knowledge – Hosted by Carahsoft and CDS Federal Services 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 2EquitiesIQ Initiates Coverage of Alliqua, Inc. 3The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 2The Sunshine Act: Necessary Regulation or Unnecessary Dysregulation? New Life Science Webinar Hosted by Xtalks and IRB Services 3Photonics R&D Leader Bob Hainsey Joins SPIE Technical Staff 2
... Madison, Wis. - Stratatech Corp. has received ... Institute on Aging , a division of the National ... gene therapy products for the use in the treatment of ... stasis and pressure ulcers. , ,It is estimated that in ...
... Brookfield, Wis.-based Fiserv, Inc. and CUNA ... delivery and presentation of CUNA Mutual's payment ... with the technology solutions offered by Fiserv ... CUNA Mutual's payment protection products, which include credit life, ...
... Wis. -- We take it for granted the lights ... and ice storms can temporarily bring down power lines and ... of us believe affordable power will always be there - ... ,If only it was as easy as flipping a switch. ...
Cached Biology Technology:Keeping Wisconsin supplied with energy won't get any easier 2Keeping Wisconsin supplied with energy won't get any easier 3
Goat polyclonal to SART3 ( Abpromise for all tested applications). Antigen: Synthetic peptide: MSNADFAKLFLRK, corresponding to C terminal amino acids 951-963 of Human SART3 Entrez Gene ID: 9...
Hamartin/TSC1 (1B2) Mouse mAb Ship: Hot Store: -20 C...
synaptotagmin XIV-like [Source:RefSeq_peptide;Acc:NP_114120] Antigen: Recombinant Protein Epitope Signature Tag (PrEST)....
BDFastImmune? IFN-gamma /CD69/CD4/CD3 Storage Temperature: Refrigerate(2 to 8C)...
Biology Products: