Navigation Links
UWM brain research supports drug development from jellyfish protein

long time as an indicator of calcium. But the protein has never been tried as a treatment to control calcium levels. Underwood believes his company is at about the 12-year mark in the typical 15-year cycle for a new drug to be developed.

Moyer's research centers on brain changes that occur as a result of aging. Specifically, he is interested in the part of the brain called the hippocampus, which is responsible for forming new memories. These capabilities not only deteriorate in neurodegenerative disorders such as Alzheimer's disease, but they also become impaired simply by aging.

Aging increases the number of "doors" that allow calcium ions to enter the cells, he said.

Moyer, who came to UW-Milwaukee from a post-doctoral position at Yale University, performs Pavlovian trace conditioning experiments to evaluate aging-related learning and memory deficits. These tasks first teach rodents to associate one stimulus with another and then test their memory of the association. During training, the stimuli are separated by a brief period of time, which requires the animal to maintain a memory of the first stimulus. The "stimulus free" period makes the task more difficult, especially for older animals.

Moyer's work also has implications outside of disease. He is able to show that at middle age, when the animal's learning ability or memory is not yet impaired, it already shows a drop in the number of neurons that contain an important calcium-binding protein.

"That cellular changes precede memory deficits indicates there is a window of opportunity for intervention before it's too late," he says. "Once the cells are lost, there is little chance of regaining normal brain function."


'"/>

Source:University of Wisconsin - Milwaukee


Page: 1 2

Related biology news :

1. Controversial drug shown to act on brain protein to cut alcohol use
2. Mouse brain cells rapidly recover after Alzheimers plaques are cleared
3. Mouse brain tumors mimic those in human genetic disorder
4. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
5. First atlas of key brain genes could speed research on cancer, neurological diseases
6. NYU study reveals how brains immune system fights viral encephalitis
7. Stem cells from brain transformed to produce insulin at Stanford
8. Birds brains reveal source of songs
9. Loves all in the brain: fMRI study shows strong, lateralized reward, not sex, drive
10. Revolutionary nanotechnology illuminates brain cells at work
11. A puzzle piece found in unraveling the wiring of the brain
Post Your Comments:
(Date:12/17/2014)... , Dec. 15, 2014 Research and Markets ... the "Samsung Galaxy S5 - Home Button Synaptics ... http://photos.prnewswire.com/prnh/20130307/600769 ... iPhone 5S, Samsung introduces for the first time a ...
(Date:12/17/2014)... DENVER , Dec. 16, 2014  Automation is fundamentally ... evident than at international borders. Over the past decade, ... veteran travelers to self process through border control via ... increasing number of airports, seaports, and land borders across ...
(Date:12/11/2014)... ST. PAUL, Minn. , Dec. 10, 2014 ... wireless physiologic monitoring, has released a new series ... needs of preclinical toxicology researchers. M series, part ... help toxicologists collect the best possible physiologic data ...
Breaking Biology News(10 mins):Samsung Galaxy S5 - Home Button Synaptics Fingerprint Sensor Technology Analysis 2Automated Border Control (ABC) Transforms the Global Travel Experience With More Than 2500 ABC eGates and APC Kiosks Deployed In Airports, Seaports, and Land Borders Worldwide 2New telemetry implants expected to change how large animal toxicology studies are conducted 2
... animals usually congregate for protection or mating or to capture ... found that the terrestrial hermit crab has a more self-serving ... and move into a larger home., All hermit crabs appropriate ... so species of land-based hermit crabs popular terrarium pets ...
... . U.S. Department of Agriculture (USDA) ... soils with manure also can help restore soils on ... land with little or no vegetation, once mined for ... Missouri, southeastern Kansas, and northeastern Oklahoma. The mining activities ...
... LAKE CITY, Oct. 25, 2012 /PRNewswire-iReach/ -- New research ... in Portland, Maine have demonstrated improvements in health behaviors ... chronic disease and rising health care costs continue to ... to reduce health risks and improve ...
Cached Biology News:Hermit crabs socialize to evict their neighbors 2Hermit crabs socialize to evict their neighbors 3Minimizing mining damage with manure 2New Study Shows That Improvements in Employee Health Behaviors Persist Over Two Years 2
(Date:1/22/2015)... zFlo Motion , a US leader ... exciting product from a new partner. STT-Systems has ... past 15 years, with offerings in the optical-motion capture, 3D ... system (inertial measurement unit), iSen, is opening eyes around the ...
(Date:1/22/2015)... Jersey , 22 de enero de 2015  El Dr. ... hoy su llamada a nominaciones para 2015. Este prestigioso ... hecho, o tiene el potencial para hacer, contribuciones destacadas ... se aceptarán hasta el 15 de marzo de 2015 ...
(Date:12/25/2014)... report “Service Quality Management and Telco Customer Experience Management ... Advancements, Worldwide Forecasts & Analysis (2014-2019)” defines and segments ... revenues. , Browse 152 market data tables, 19 ... “Service Quality Management (SQM) and Telco Customer Experience Management ...
(Date:12/24/2014)... (PRWEB) December 23, 2014 “Preparative ... Gas, HPLC, Flash), Consumables (Columns, Solvents, Buffers, Valves, ... Food & Agriculture) - Forecasts to 2019” provides ... challenges, opportunities, current market trends, and strategies impacting ...
Breaking Biology Technology:3D Motion Capture Just Got Easy 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 2El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 3El Dr. Paul Janssen Award for Biomedical Research emite su llamada a los nominados para 2015 4Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 2Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 3Service Quality Management Market worth $2.1 Billion & Telco Customer Experience Management Market worth $2.3 Billion by 2019 – New Report by MarketsandMarkets 4Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 2Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 3Preparative and Process Chromatography Market is expected to reach $9 billion by 2019 - New Report by Marketsandmarkets 4
... , ROCKAWAY, N.J., Dec. 14 The third edition ... , published by the Infusion Nurses Society (INS), includes ... are a group of chemotherapy medications including daunorubicin, doxorubicin, idarubicin ... various types of cancer since the early 1970s.(2) ...
... SAN CARLOS, Calif., Dec. 14 Nektar Therapeutics (Nasdaq: ... to serve on its board of directors. Winger is ... experience in corporate management, financial and business strategy. , "Dennis ... in the company,s evolution," said Howard W. Robin, President and ...
... , , BRUSSELS, December 14 ... Assessing the Lifestyles of,Women With Rheumatoid Arthritis in Seven Major Industrialized Countries , , ... disease, impacts their enjoyment of the festive season, ... preparing holiday food, writing cards and wrapping presents most, ...
Cached Biology Technology:Infusion Nurses Society References Totect(R) (Dexrazoxane For Injection) as the Only Antidote for the Treatment of Anthracycline Extravasation 2Infusion Nurses Society References Totect(R) (Dexrazoxane For Injection) as the Only Antidote for the Treatment of Anthracycline Extravasation 3Infusion Nurses Society References Totect(R) (Dexrazoxane For Injection) as the Only Antidote for the Treatment of Anthracycline Extravasation 4Infusion Nurses Society References Totect(R) (Dexrazoxane For Injection) as the Only Antidote for the Treatment of Anthracycline Extravasation 5Dennis Winger Joins Nektar Therapeutics' Board of Directors 2Dennis Winger Joins Nektar Therapeutics' Board of Directors 3Rheumatoid Arthritis Patients Want Pain-Free Days at Christmas 2Rheumatoid Arthritis Patients Want Pain-Free Days at Christmas 3Rheumatoid Arthritis Patients Want Pain-Free Days at Christmas 4
... use in refrigerators, freezers, or liquid nitrogen. Conveniently sized ... for color coding to project, user, lab, etc. Holes ... cool air circulation. Supplied with 9 x 9 (12.7 ... Box dimensions: 13 x 13 x 5.1 cm H ...
RABBIT ANTI BACTERIAL HISTIDASE...
2,4-Dinitrophenyl hapten is conjugated to BSA (Bovine Serum Albumin) protein through lysine....
See product name for description....
Biology Products: