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USC researchers investigate protein that protects tumors

s used to develop Herceptin, one of the first biological treatments for breast cancer. Herceptin targets the her2 protein, which is found on the surface of tumor cells about 20 percent of the time, says Gill.

The her2 protein played a role in this study as well. That protein, along with several of its cousins, was found to activate EphB4, he said. "There are certain growth factors that can make this particular protein (EphB4) go up," Gill says. "We are learning more about how this protein is turned on and off in a cancer cell."


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Source:University of Southern California


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