Navigation Links
UQ scientists break new ground in fight against infection & chronic disease

University of Queensland (UQ) researchers are on track to develop new treatments for acute infections, chronic inflammatory diseases and cancer.

The research could revolutionise treatments for conditions such as bird flu, arthritis, and inflammatory bowel disease, by using a mechanism that gives the human body a more rapid response to infections.

The discovery, made by four researchers from UQ's Institute for Molecular Bioscience (IMB), will be published in the December 2nd edition of the world's leading scientific journal Science.

It involves cells in the front line of defence against infection, called macrophages, releasing messengers to fight and kill disease-causing microbes.

IMB researchers Professor Jennifer Stow, Dr Rachael Murray, Mr Jason Kay and Mr Daniele Sangermani discovered macrophages use a single pathway to orchestrate two different responses to disease.

Professor Stow said when disease-causing microbes infect the body, macrophages respond by engulfing and killing the microbes.

"The cells also release chemical messengers to boost immunity," Professor Stow said.

She said the research was made possible by advanced technologies at the IMB such as live cell microscopy and gene analysis, which are unique in Queensland.

"By using these technologies we were able to show, for the first time, both actions occur simultaneously and a common cellular pathway is used for releasing messengers and for eating microbes," she said.

"This adaptation ensures the whole immune system responds to an infection in the most efficient and rapid way possible.

"In some situations, this clever time-saving device could be a life-saver."

Professor Stow said the study also looked at why having a "hair-trigger" immune response is a dangerous thing.

She said these chemical messengers were among the agents that caused patients to die from acute infections like bird flu and to acqu
'"/>

Source:Research Australia


Page: 1 2

Related biology news :

1. Wisconsin scientists grow critical nerve cells
2. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
3. UAB scientists discover the origin of a mysterious physical force
4. Fox Chase Cancer Center scientists identify immune-system mutation
5. Weizmann Institute scientists develop a new approach for directing treatment to metastasized prostate cancer in the bones.
6. U-M scientists find genes that control growth of common skin cancer
7. UCLA scientists transform HIV into cancer-seeking missile
8. RNA project to create language for scientists worldwide
9. Carnegie Mellon scientists develop tool that uses MRI to visualize gene expression in living animals
10. To control germs, scientists deploy tiny agents provocateurs
11. Leprosy microbes lead scientists to immune discovery
Post Your Comments:
(Date:12/10/2014)... , Dec. 9, 2014  Wake Forest Baptist Medical ... building for its School of Medicine. Funding for this ... capital campaign that will be publicly launched next summer. ... located in the former 60 series R.J. Reynolds Tobacco ... Quarter. Construction will begin immediately with plans to be ...
(Date:12/10/2014)... Research and Markets ( http://www.researchandmarkets.com/research/xclcvw/biometrics_market ... "Biometrics Market in Japan 2014-2018" report to ... The integration of biometrics and ... and upgradation of the driver,s license is one ... Besides the aforementioned projects, biometrics is being used ...
(Date:12/5/2014)... 4, 2014 Increased emphasis on product ... new testing and inspection technologies. The convergence of ... a range of innovative test solutions. This trend ... Y, which is generally more inclined towards communication, ... development strategies of test equipment vendors will cater ...
Breaking Biology News(10 mins):Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 2Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 3Wake Forest Baptist to Build New Medical Education Facility In Wake Forest Innovation Quarter 4Biometrics Market in Japan 2014-2018: Key Vendors are DDS, Fujitsu, Hitachi and NEC 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 2Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 3Emerging Technologies Enable Smarter Monitoring of Assets, Push Industrial Testing, Inspection and Monitoring Market 4
... Researchers at the University of Alabama at Birmingham (UAB) ... grow and remodel themselves to stay strong, a finding ... osteoporosis drugs, the researchers said The coupling factor ... or TGF beta-1. Previously, scientists had searched for but ...
... "Push your finger as hard as you can against the ... slowly - follow the ticking clock. Now faster. Now faster." ... experiment that casts doubt on old ideas about mechanisms to ... explain why manual dexterity is so vulnerable to aging and ...
... Ore. A 700-mile security wall under construction along ... the movement and "connectivity" of wildlife, biologists say, and ... of some species. However, technology and alterations to ... to move more freely between the two countries, the ...
Cached Biology News:UAB study reveals bone coupling factor key to skeletal health 21-finger exercise reveals unexpected limits to dexterity 21-finger exercise reveals unexpected limits to dexterity 3US-Mexico border wall could threaten wildlife species 2US-Mexico border wall could threaten wildlife species 3US-Mexico border wall could threaten wildlife species 4
(Date:12/24/2014)... 2014 On Friday, December 19, ... the Omnibus and Continuing Resolution Appropriations Act of ... a condition eligible to receive funding through the ... the Department of Defense (DoD). The Hydrocephalus Association ... Capitol Hill, is celebrating this victory for the ...
(Date:12/24/2014)... 23, 2014 Nashville Fertility Center announced ... treasurer for the American Society for Reproductive Medicine (ASRM), ... research in reproductive medicine. In his new role ... the executive board and will have a voice in ... has actively supported ASRM since 1984 when he joined ...
(Date:12/24/2014)... , Dec. 23, 2014 China Biologic ... "Company"), a leading fully integrated plasma-based biopharmaceutical company ... that its majority-owned subsidiary, Shandong Taibang Biological Products ... certification from the China Food and Drug Administration ... facility. As previously disclosed in the Company,s public ...
(Date:12/24/2014)... , Dec. 23, 2014 Sigma-Aldrich ... that the waiting period under the Hart-Scott-Rodino Antitrust ... acquisition expired on December 22, 2014, thereby completing ... requirement for the acquisition of the Company by ... antitrust clearance satisfies another condition to closing the ...
Breaking Biology Technology:Rare Brain Condition Now Eligible for Department of Defense Research Dollars 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 2Nashville Fertility Center Announces Dr. George A. Hill Selected to Serve as ASRM Treasurer for 2014-15 3China Biologic Receives GMP Certification for New Coagulation Factor Facility 2China Biologic Receives GMP Certification for New Coagulation Factor Facility 3Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 2Acquisition of Sigma-Aldrich by Merck KGaA, Darmstadt, Germany, Receives U.S. Antitrust Clearance 3
... Dissolve Powder Antacid Delivers Faster Relief, ... Increased Convenience and Great Taste, PITTSBURGH, April ... integrated marketing campaign,for the new TUMS(R) QuikPak(TM), the first and ... QuikPak campaign, part of,a larger new "Bring It On" brand ...
... - MIGENIX Inc.,(TSX: MGI, OTC: MGIFF), a clinical-stage ... Dorsman to its Board of Directors. Mr.,Dorsman is ... a,financial consulting firm in Vancouver, which advises companies ... overall business,strategies. Prior to founding his consulting firm ...
... Sirion Therapeutics, Inc., a,privately held ophthalmic-focused biopharmaceutical company, ... targeted for the,treatment of retinal diseases will be ... for Research in Vision and Ophthalmology (ARVO),April 27 ... http://www.newscom.com/cgi-bin/prnh/20080220/CLW064LOGO ), "We are very ...
Cached Biology Technology:New TUMS(R) QuikPak(TM) Campaign Offers Innovative Heartburn Relief with a Little Help from the Jetsons 2MIGENIX Appoints Pieter Dorsman to Board of Directors 2Sirion Therapeutics Preclinical Studies: Two New Potential Advances in Treatment of Retinal Diseases to be Presented at ARVO 2Sirion Therapeutics Preclinical Studies: Two New Potential Advances in Treatment of Retinal Diseases to be Presented at ARVO 3
Mouse monoclonal antibody raised against a partial recombinant PRG4. NCBI Entrez Gene ID = PRG4...
... selection system for recombinant identification. Recombinant selection ... need for costly color screening. This quick ... accuracy in recombinant selection. pLivSelect is also ... This cloning kit is customized as ...
The F40 pump maintenance kit is used to service one F40 pump of a BioLogic DuoFlow workstation. It includes 2 piston seals, 4 check valves, seal removal tool, and 2 O-rings....
... HDAC8 Regulation of gene expression ... as DNA methylation, ATP-dependent chromatin remodeling, ... which include the dynamic acetylation and ... residues present in the tail of ...
Biology Products: