Navigation Links
UIC researchers show protein routes messages in nerve cells

Nerve cells relay messages at blink-of-the-eye speeds by squirting chemicals called neurotransmitters across tiny gaps called synapses to awaiting message receptors. But lots of different receptors and neurotransmitters work simultaneously. Which goes where to send the proper message?

Research reported in the July 20 issue of the Journal of Neuroscience (released online July 13) by a team led by David Featherstone, a University of Illinois at Chicago assistant professor of biology, provides some important preliminary answers.

Featherstone and UIC post-doctoral associate Kaiyun Chen, along with German researchers Carlos Merino and Stephan Sigrist at the European Neuroscience Institute in Goettingen, chose the common fruit fly as their research animal and the chemical glutamate -- present in fruit flies and humans -- as their neurotransmitter of choice.

"It's still unknown how glutamate receptors get to precisely where they're supposed to go on a cell in order to mediate the neurotransmission," said Featherstone. "If the receptors are not in the right place, then the message becomes less efficient. Or if receptors are the wrong type, the message could get completely mixed up."

Such mix-ups can lead to a condition called synaesthesia, where, for example, a sound may have taste, or an image may have a smell. The molecular basis of this condition remains unknown.

"It all comes down to the receptors being in the right place at the right time," said Featherstone. "So our question was, how do these receptors know where they're supposed to go at the time they're supposed to be there?"

Fruit flies proved to be ideal test animals for answering the question because a synapse called the neuromuscular junction in the fly works much like synapses in human brain cells.

"We can quickly mutate the flies," said Featherstone. "We looked among thousands of them for those without the glutamate receptors in the right place at the righ
'"/>

Source:University of Illinois at Chicago


Page: 1 2

Related biology news :

1. NYU researchers simulate molecular biological clock
2. Vital step in cellular migration described by UCSD medical researchers
3. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
4. UCSD researchers maintain stem cells without contaminated animal feeder layers
5. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
6. New protein discovered by Hebrew University researchers
7. First real-time view of developing neurons reveals surprises, say Stanford researchers
8. Agilent Technologies releases automated literature search tool for biology researchers
9. Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
10. Yale researchers identify molecule for detecting parasitic infection in humans
11. US life expectancy about to decline, researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: UIC researchers show protein routes messages nerve cells

(Date:8/18/2015)... , Aug. 18, 2015  Navitas today ... contributor to the Submission Content Management webinar ... a non-profit forum. Dedicated to the Implementation of ... neutral platform for industry, vendors, health authorities, ... and work towards a standard method of ...
(Date:8/12/2015)... , August 12, 2015 ... of mobile payment innovation and advanced biometrics technology is ... the way consumers rely on using their credit cards, ... reinventing the future for payment services led by companies ... NXTD ), :  Google, Inc. (NASDAQ: GOOG ), ...
(Date:8/10/2015)... Germany , August 10, 2015 /PRNewswire/ ... world leader in Eye Tracking Technology for more than ... Eye Tracking Platform for integration into all consumer display ... designs for seamless integration of eye tracking into consumer ... and augmented reality smart glasses. Omnivision,s leading sensor technology ...
Breaking Biology News(10 mins):Navitas, a Key Contributor in IRISS Forum Webinar 2Navitas, a Key Contributor in IRISS Forum Webinar 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 2Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 3Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 4Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 5Digital Wallet Devices & Mobile Payment Management Services Gain a Distinct Advantage in the Digital Payment Evolution as Demand Continues to Grow 6SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 2SMI Completes OEM Eye Tracking Platform to Cover All Consumer Displays 3
... YORK (September 10, 2008)A set of stripy legs in a ... to cheer about, say researchers from the Wildlife Conservation Society. ... has survived in the Democratic Republic of Congo,s Virunga National ... poaching. "This is the first time this species ...
... feet below the Earth,s surface, in a circular tunnel ... and back again, scientists at the Large Hadron Collider ... in Geneva fired the first beams of protons that ... contingent of more than 40 faculty members, graduate students, ...
... a critical stage of pregnancy implantation of the embryo ... vital to the growth of new blood vessels that sustain ... quantities in the presence of estrogen, the embryo is unlikely ... the mechanism by which the steroid hormone estrogen spurs cell ...
Cached Biology News:Photo reveals rare okapi survived poaching onslaught 2UC Santa Barbara has key role in Large Hadron Collider project 2UC Santa Barbara has key role in Large Hadron Collider project 3UC Santa Barbara has key role in Large Hadron Collider project 4Gap junction protein vital to successful pregnancy, researchers find 2
(Date:9/4/2015)... Research and Markets ( ... "Biopreservation Market by Product, Biospecimen, Application and ... report to their offering. The global ... Million by 2020 from USD 2,150.48 Million in ... 2015 and 2020. Biopreservation ensures the ...
(Date:9/3/2015)... ... September 03, 2015 , ... The latest addition to the ... and verifies labels automatically. Companies in the pharmaceutical and healthcare industry can use the ... 500 per minute. The Label Serialization Station can be fully integrated into the production ...
(Date:9/3/2015)... 3, 2015  Vermillion, Inc. (NASDAQ: VRML ), ... announced that Herbert Fritsche , Ph.D., the Lab ... the recipient of the 2015 Abbott Award, given by ... outstanding contributions to the field of basic or clinical ... 5 th in Zakopane, Poland ...
(Date:9/3/2015)... , September 3, 2015 According ... by System (LC (HPLC, UHPLC, Flash), GC, Other Components ... Syringe Filters, Vials) - Analysis & Global Forecasts to ... expected to reach around 9.223 Billion by 2020 from ... 5.5%. Browse 141 tables and 36 figures ...
Breaking Biology Technology:Global Biopreservation Market 2015-2020 - Product, Biospecimen, Application and End User Analysis of the $3.73 Billion Industry 2Global Biopreservation Market 2015-2020 - Product, Biospecimen, Application and End User Analysis of the $3.73 Billion Industry 3Print and Verify Labels On The Production Line With New Label Serialization Stations 2Print and Verify Labels On The Production Line With New Label Serialization Stations 3Vermillion Announces Dr. Herbert Fritsche as Recipient of the 2015 Abbott Award from the International Society of Oncology and Biomarkers 2Chromatography Instruments Market Worth $ 9.223 Billion by 2020 2Chromatography Instruments Market Worth $ 9.223 Billion by 2020 3Chromatography Instruments Market Worth $ 9.223 Billion by 2020 4
... 23 MedShape Solutions, Inc. announced today the first FDA ... shape memory PEEK Altera(TM) material. The Morphix(TM) Suture Anchor ... select U.S. markets in the coming months. Over $2.5B ... of orthopedics. These devices range from spinal cages to ...
... , , AUSTIN, Texas, ... management software for the Life Sciences industry, today announced it has ... its Protocols for Animal Studies which is focused on the management ... , , Developed to address the research and ...
... , , CARLSBAD, ... soil, water and microbial nucleic acid purification, announces the launch of ... high-quality total RNA from a variety of filtered water samples. ... in the developing fields of water safety testing, microbial community analysis ...
Cached Biology Technology:MedShape Solutions, Inc. Announces First FDA-cleared Shape Memory PEEK Device; Closing of $10M Equity Offering 2TOPAZ Technologies Protocols for Animal Studies Software Drives Customer Conversions 2MO BIO Laboratories, Inc. Launches PowerWater(R) RNA Isolation Kit 2
... you can identify and characterize high-value, low-abundant ... The Agilent Multiple Affinity Removal System allows ... from human serum, plasma, CSF samples and ... this revolutionary system, you can: ...
... intended for laboratory research use only. ... buffered formalin and embedded in paraffin. ... certified pathologists. Tissue cores were removed ... a new recipient paraffin block, in an ...
... RNA Spike-In Kit contains in vitro synthesized, ... complementary control probes on Agilents microarrays, with ... as a positive microarray control in the ... kit is a required component of the ...
... is the industry standard microarray image analysis ... imaging and analysis tools, visualizations, automation capabilities, ... is included with every GenePix scanner, and ... scanners and all types of arrays. A ...
Biology Products: