Navigation Links
UI researcher studies deafness in fruit flies, humans

University of Iowa Biological Sciences Professor Daniel F. Eberl and his colleagues at Duke University have uncovered genetic defects leading to deafness in fruit flies that may shed light on deafness in humans. Their research paper, "Myosin VIIA Defects, which Underlie the Usher 1B Syndrome in Humans, Lead to Deafness in Drosophila," is scheduled for publication in the May 10 issue of the journal Current Biology.

Eberl says their recent work -- showing that loss of function in the Myosin VIIA gene leads to complete deafness in fruit flies -- has brought scientists one step closer to understanding how such mutations result in inner-ear abnormalities and deafness in humans.

"Myosin VIIA was one of the first human hereditary deafness genes to be identified. But it is not clear exactly how this molecule works in the human ear," he says.

Previous evidence suggested that fruit flies and humans rely on the same genes to develop their auditory organs, which in the fruit fly is in the antenna. Eberl's research shows that at least one molecular component specialized for hearing function, myosin VIIA, is conserved in these ears.

In looking for clues to inherited deafness in humans, Eberl begins with the "love song" of the fruit fly. Although they may seem an odd choice, the fruit fly and its love song are very effective tools for learning about the molecular and cellular mechanisms involved in hearing in insects and animals, including humans, says Eberl, who is trying to identify the genes responsible for hearing in fruit flies.

Whether or not mutant fruit flies can hear the fruit fly love song (actually a vibrating wing) enables Eberl to evaluate the function of genes responsible for hearing. He and his graduate student, Sokol Todi, implant electrodes into the antennas of the flies, and record the voltages the receptor cells generate as the flies listen to the love song. By comparing the electrical impulses generated by the normal flies
'"/>

Source:University of Iowa


Page: 1 2

Related biology news :

1. U of M researcher examines newly emerging deadly disease
2. NYU researchers simulate molecular biological clock
3. Vital step in cellular migration described by UCSD medical researchers
4. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
5. UCSD researchers maintain stem cells without contaminated animal feeder layers
6. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
7. New protein discovered by Hebrew University researchers
8. First real-time view of developing neurons reveals surprises, say Stanford researchers
9. Agilent Technologies releases automated literature search tool for biology researchers
10. Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
11. Yale researchers identify molecule for detecting parasitic infection in humans
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: researcher studies deafness fruit flies humans

(Date:8/28/2014)... FASEB MARC (Maximizing Access to Research Careers) Program ... Society of Human Genetics from October 18 22, ... meant to promote the entry of students, post doctorates ... the basic science community and to encourage the participation ... Genetics. This year MARC conferred 16 awards totaling ...
(Date:8/28/2014)... MD FASEB MARC (Maximizing Access to Research ... for the Genetics Society of America,s 27th Annual ... October 3, 2014 in Pacific Grove, California. ... of students, post doctorates and scientists from underrepresented ... community and to encourage the participation of young ...
(Date:8/28/2014)... Aug. 28, 2014  Privacy Advocate and Senior Staff ... Lynch , joins the lineup of biometric and mobile ... Biometrics UnPlugged Executive Summit in Tampa, Florida ... Previously announced speakers include Steven Rahman, Director, Technology and Strategy ... at Experian. The theme of this year,s event is ...
Breaking Biology News(10 mins):Biometrics UnPlugged Welcomes the Electronic Frontier Foundation's Jennifer Lynch to the Mobility at the Crossroads of Commerce and Privacy Summit 2
... Cells trying to keep pace with constantly changing environmental ... their genomic integrity and allowing enough genetic flexibility to ... at the Stowers Institute for Medical Research were able ... unstable, readily acquiring or losing whole chromosomes to enable ...
... today finds that tropical vegetation contains 21 percent more ... remote sensing and field data, scientists from Woods Hole Research ... able to produce the first "wall-to-wall" map (with a spatial ... of forests, shrublands, and savannas in the tropics of Africa, ...
... of rare, endemic species in the Central Andes remain ... climate change, according to a Duke University-led international study. ... particularly vulnerable to changes in the environment or climate. ... percent of the areas with high numbers of these ...
Cached Biology News:That which does not kill yeast makes it stronger 2That which does not kill yeast makes it stronger 3The good news about carbon storage in tropical vegetation 2The good news about carbon storage in tropical vegetation 380 percent of 'irreplaceable' habitats in Andes unprotected 2
(Date:8/29/2014)... Hills, NY (PRWEB) August 29, 2014 ... Burnt Hills Veterinary Hospital are seeking candidates to participate ... dogs with osteoarthritis. The ultimate goal of this ... donor stem cells into one or two arthritically affected ... treated joints. , Candidates for the current investigational ...
(Date:8/29/2014)... Boston, MA, San Antonio, TX (PRWEB) August 29, ... audited, ISO 9001:2008 and ISO 13485:2003 certified, GAMP® ... it has been awarded an international Phase II ... patients with non-Hodgkin’s lymphoma. , Throughout this trial, ... services including, but not limited to, protocol and ...
(Date:8/28/2014)... “This kit has an improved extraction efficiency and provides ... ppb,” said Mark Tess, PhD, Mycotoxin Product Manager for Charm ... and USDA-GIPSA inspection agencies that have a need to detect ... in a matter of minutes with nothing but our equipment ... and grain before accepting it, but they no longer have ...
(Date:8/28/2014)... Willow Grove, PA (PRWEB) August 28, 2014 ... talent, and create a culture that will allow individuals ... that are becoming increasingly important for employers looking to ... life science industries are embracing this trend, as the ... the fabric of a company, which will have real ...
Breaking Biology Technology:Burnt Hills Veterinary Hospital Seeks Candidates for an Investigational Study of Stem Cells for Dogs with Arthritis 2Intrinsic Imaging Awarded Phase II Clinical Trial to Assess New Treatment for Non-Hodgkin’s Lymphoma 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 2Klein Hersh International Leads Philadelphia Area Life Science Industry in Company Culture 3
... GAITHERSBURG, Md., Nov. 12 MaxCyte, Inc.,the pioneer ... it will be hosting a live discussion with ... assays for drug discovery.,The discussion is open to ... on,Thursday, November 13th from 2:00-3:00EST., One of ...
... Surgery Institute Is ... in Moscow, MOSCOW, Nov. 12 A Vermont eye ... he implanted the,Crystalens HD into a 49 year old Russian ... Randolph, Vermont performed the surgery at the,Ninth International Conference on ...
... Recommendations, BETHLEHEM, Pa., Nov. 12 ... Marketing, Infusion Systems Division and Helen,Chang, PharmD, ... Braun Medical,Inc. (B. Braun), a global leader ... B. Braun at the Institute for Safe ...
Cached Biology Technology:MaxCyte Hosts Live Discussion with Industry Experts on the Challenges in Developing Cell-Based Screening Assays for Drug Discovery 2Vermont Surgeon Implants First Accommodating Crystalens in Russia 2B. Braun Directors Participate at First ISMP National Smart Pump Safety Summit 2B. Braun Directors Participate at First ISMP National Smart Pump Safety Summit 3
... choice of PDMS Stamps (3 PDMS micropatterned ... micron squares or 100 um x 10 ... lines, 3 PDMS nano-patterned stamps with depth ... pitch of 400 nm, or 3 PDMS ...
Request Info...
RECOMBINANT EQUINE IL-4 Product Type: Recombinant Protein...
Request Info...
Biology Products: