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UF researchers kill resistant bugs one bandage at a time

s bacteria from reaching a wound and recolonizing there. UF researchers and scientists from the company presented their findings at the Wound Healing Society's annual meeting earlier this year, and the coating's ability to wipe out harmful bacteria and fungi was later confirmed in independent laboratory tests.

The coating also was designed to keep bacteria from becoming resistant to it. Popular silver dressings work well as a bacterial barrier but release ions that allow resistance to develop, Schultz said.

The structure of the microbicidal coating and the complexity of the process make it nearly impossible for bacteria to become resistant to it, Schultz said. The coating comprises thousands of nitrogen clusters that permanently bond to substances such as gauze and fabric. Other dressings use a process that allows molecules to diffuse into the air and into the wound, which can slow healing and increases the chance germs will develop resistance.

"These technologies are especially timely given the threats that are facing the American public, such as antibiotic-resistant bugs occurring in hospitals across the world," said Christopher Batich, Ph.D., a UF professor of biomedical engineering and one of the coating's inventors. "This has the potential to be used widely."

The coating also does what it was created to do - aids healing, Schultz said. When added to gauze, it makes the material superabsorbent, pulling excess moisture away from the sore. And its microbicidal properties keep bacteria from growing in the wound and protect it from infections. Bacteria in a wound "is like jet fuel for these bugs," Schultz said.

"Gauze is still the most commonly used dressing for wounds," he said. "But the problem with gauze is when it absorbs fluid, it forms a great avenue for bacteria and fungus to grow. This treatment actually makes the gauze absorb a little more fluid, (but) it'll keep the wound cleaner because it will keep the bacteria fro
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Source:University of Florida


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