Navigation Links
UCSD team discovers specialized, rare heart stem cells in newborns

The first evidence of cardiac progenitor cells ?rare, specialized stem cells located in the newborn heart of rats, mice and humans ?has been shown by researchers at the University of California, San Diego (UCSD) School of Medicine. The cells are capable of differentiation into fully mature heart tissue.

Called isl1+ cells, these cardiac progenitor cells are stem cells that have been programmed to form heart muscle during fetal growth. Until this new discovery, the cells were thought to be absent after birth. However, the UCSD team discovered a small number of the specialized stem cells remained embedded in a region of the newborn heart called the atrium. They also determined that the cells could be expanded into millions of progenitor cells by growing them on a layer of neighboring heart cells called fibroblasts.

Published in the February 10, 2005 issue of the journal Nature, the research identified the isl1+ progenitor cells in the tissue of newborn rats and mice, and then in heart tissue taken from five newborn human babies undergoing surgery for congenital heart defects.

Study author Sylvia Evans, Ph.D., a member of the UCSD Institute of Molecular Medicine (IMM) and professor of pharmacology, and co-first author Alessandra Moretti, Ph.D., IMM member, explained that the cells are programmed to become spontaneously beating cardiac muscle cells simply by exposure to other neighboring heart cells.

And, since these rare cardiac progenitor cells are found in regions of the atrium that are normally discarded during routine cardiac surgery, the discovery raises the possibility that an individual could receive their own cardiac stem cells to correct a wide spectrum of pediatric cardiac diseases, according to co-first authors Moretti and Karl-Ludwig Laugwitz, M.D., a Heisenberg-Scholar of the German Research Foundation.

"Conceptually, these cells could provide a cell-therapy based approach to pediatric cardiac disease, which is new fo
'"/>

Source:University of California, San Diego


Page: 1 2 3

Related biology news :

1. University of Nevada, Reno research team discovers hormone that causes malaria mosquito to urinate
2. MIT chemist discovers secret behind natures medicines
3. Mayo Clinic collaboration discovers protein amplifies DNA injury signals
4. Expedition discovers marine treasures
5. Team discovers possible universal strategy to combat addiction
6. Nobelist discovers antidepressant protein in mouse brain
7. Joslin discovers signs of residual islet cell function in people with long-term type 1 diabetes
8. Contrary to common wisdom, scientist discovers some mammals can smell objects under water
9. U of S Vaccine and Infectious Disease Organization team discovers key step in flu virus replication
10. LSU professor discovers new species
11. Mayo discovers protein as potential tactic to prevent tumors
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: UCSD team discovers specialized rare heart stem cells newborns

(Date:5/25/2015)... -- Australia,s market for wearable technologies is considered to be ... of several trials and prototypes. The release of the ... ignite interest in wearables as well as accelerate sales ... This in turn will spur greater innovation from other ... vendors and distributors. Photo - ...
(Date:5/22/2015)... 2015  NXT-ID, Inc. (NASDAQ: NXTD ) ("NXT-ID" or ... ending its promotional pricing and making the Wocket generally available ... Savin , Head of Marketing said, "We,ve extended the opportunity ... end of May. To get your wocket at this special ... the store on June 1, you,ll receive a unique code ...
(Date:5/22/2015)... DALLAS , May 22, 2015 ... Recognition Market by Solution (2D, 3D, Thermal, Emotion, Forensic), by ... End User (Government and Utilities, Consumer and Home) - ... Market to grow from $2.77 Billion in 2015 to ... Browse 79 market data Tables and ...
Breaking Biology News(10 mins):Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 2Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 3Australian wearables market to grow at CAGR of 78%; revenue of A$1 billion by 2018, says Frost & Sullivan 4NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 2NXT-ID, Inc Announces Retail Price For Wocket Smart Wallet And Extends Discounted Promotional Price Till End Of May 3Facial Recognition Market Worth $6.19 Billion by 2020 2Facial Recognition Market Worth $6.19 Billion by 2020 3
... fish do it. But Prof. Yossi Loya from Tel Aviv ... to discover that Japanese sea corals engage in "sex switching" ... survival of fragile sea corals ― essential to all life ... In times of stress like extreme hot spells, the ...
... these articles, please contact Kevin Stacey at 773-834-0386 or ... LIE ABOUT THEIR INTENTIONS? An article by ... signals an intent to attack, chances are it,s not ... mathematical models that predict animals have a significant incentive ...
... . , Montreal, February 19, 2009 A major ... a study published in the journal Nature , two Universit ... universal molecular machine, the ribosome, managed to self-assemble as a critical ... the ribosome is a complex structure it features a clear hierarchy ...
Cached Biology News:Changing sexes on the sea floor 2Honest crabs, power to the hungry, nice mice and clever meerkats: News from the American Naturalist 2Honest crabs, power to the hungry, nice mice and clever meerkats: News from the American Naturalist 3Life secret exposed: Scientists unlock mystery of molecular machine 2
(Date:5/21/2015)... May 21, 2015 Veolia’s environmental ... exclusive North American distribution agreement with VWR to ... , With more than 160 years of experience, ... services for laboratory and production facilities, has cultivated ... and differentiated services to enable science. Endetec’s ...
(Date:5/20/2015)... SAN FRANCISCO, Calif. , May 20, 2015 ... VCYT ) today presented preliminary data demonstrating the ... distinguish idiopathic pulmonary fibrosis (IPF) from other interstitial ... The findings suggest the classifier,s potential to help ... surgery to resolve ambiguity in IPF diagnosis – ...
(Date:5/20/2015)... Wayland, MA (PRWEB) May 20, 2015 ... in history, especially for lawns. US Patented Pearl’s ... rescue for lawns around the country that are coming ... technology that addresses a number of major global concerns ... is the “non-grass” grass – the alternative to the ...
(Date:5/20/2015)... , May 20, 2015  Select Medical Corporation ... Federal Trade Commission granted early termination of the ... Act of 1976, as amended, applicable to the ... Corporation, a joint venture that Select has created ... As previously announced, MJ Acquisition Corporation has ...
Breaking Biology Technology:Veolia’s TECTA™ B16 Instrument for E. Coli Detection is Offered Exclusively Through VWR 2Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 2Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 3Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 4Veracyte Presents Preliminary Data Demonstrating Ability of Molecular Classifier to Improve Non-Surgical IPF Diagnosis Using Bronchoscopy Samples 5Breakthrough 4th Generation Low Maintenance Lawn Seed Offers Solution to California Drought 2Select Medical Corporation's Proposed Acquisition of Concentra Inc. through Joint Venture with Welsh Carson Receives Antitrust Clearance 2
... NEW YORK, April 3 /PRNewswire-Asia-FirstCall/ -- China Agri-Business, ... agricultural,application products through its operating company in China, ... 31,2008. , Revenue for ... a,decrease of 3.8% as compared to $3,037,414 for ...
... CAMBRIDGE, Mass., April 3 Verenium Corporation (Nasdaq: ... development of high-performance specialty enzymes and next-generation cellulosic ... of Verenium,s demonstration-scale facility in Jennings, Louisiana, and ... with BP, Verenium is now consolidating its research ...
... tiny wires with a diameter as small as ... for devices of the future, both in technology like ... circuits for next generation of electronics. But in order ... must be precisely controlled, and researchers must better understand ...
Cached Biology Technology:China Agri-Business Announces 2008 Operating Results 2China Agri-Business Announces 2008 Operating Results 3China Agri-Business Announces 2008 Operating Results 4China Agri-Business Announces 2008 Operating Results 5Verenium Announces Organizational Changes 2Verenium Announces Organizational Changes 3Researchers peer into nanowires to measure dopant properties 2
VAP-1 (S-13)...
Human SPARC-like 1 Biotinylated Affinity Purified PAb...
... PGE2-d4 contains 4 deuterium atoms at the ... is intended for use as an internal ... (PGE2) by GC- or LC-mass spectrometry. PGE2 ... of arachidonic acid and one of the ...
Request Info...
Biology Products: