Navigation Links
UCSD team discovers specialized, rare heart stem cells in newborns

The first evidence of cardiac progenitor cells ?rare, specialized stem cells located in the newborn heart of rats, mice and humans ?has been shown by researchers at the University of California, San Diego (UCSD) School of Medicine. The cells are capable of differentiation into fully mature heart tissue.

Called isl1+ cells, these cardiac progenitor cells are stem cells that have been programmed to form heart muscle during fetal growth. Until this new discovery, the cells were thought to be absent after birth. However, the UCSD team discovered a small number of the specialized stem cells remained embedded in a region of the newborn heart called the atrium. They also determined that the cells could be expanded into millions of progenitor cells by growing them on a layer of neighboring heart cells called fibroblasts.

Published in the February 10, 2005 issue of the journal Nature, the research identified the isl1+ progenitor cells in the tissue of newborn rats and mice, and then in heart tissue taken from five newborn human babies undergoing surgery for congenital heart defects.

Study author Sylvia Evans, Ph.D., a member of the UCSD Institute of Molecular Medicine (IMM) and professor of pharmacology, and co-first author Alessandra Moretti, Ph.D., IMM member, explained that the cells are programmed to become spontaneously beating cardiac muscle cells simply by exposure to other neighboring heart cells.

And, since these rare cardiac progenitor cells are found in regions of the atrium that are normally discarded during routine cardiac surgery, the discovery raises the possibility that an individual could receive their own cardiac stem cells to correct a wide spectrum of pediatric cardiac diseases, according to co-first authors Moretti and Karl-Ludwig Laugwitz, M.D., a Heisenberg-Scholar of the German Research Foundation.

"Conceptually, these cells could provide a cell-therapy based approach to pediatric cardiac disease, which is new fo
'"/>

Source:University of California, San Diego


Page: 1 2 3

Related biology news :

1. University of Nevada, Reno research team discovers hormone that causes malaria mosquito to urinate
2. MIT chemist discovers secret behind natures medicines
3. Mayo Clinic collaboration discovers protein amplifies DNA injury signals
4. Expedition discovers marine treasures
5. Team discovers possible universal strategy to combat addiction
6. Nobelist discovers antidepressant protein in mouse brain
7. Joslin discovers signs of residual islet cell function in people with long-term type 1 diabetes
8. Contrary to common wisdom, scientist discovers some mammals can smell objects under water
9. U of S Vaccine and Infectious Disease Organization team discovers key step in flu virus replication
10. LSU professor discovers new species
11. Mayo discovers protein as potential tactic to prevent tumors
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: UCSD team discovers specialized rare heart stem cells newborns

(Date:1/22/2015)... YORK and POINT ROBERTS, Washington ... news source covering leading sectors including technology and tech stocks, ... Privacy marketplace featuring master pickpocket and security consultant Apollo ... is stolen and talks about the Wocket™ biometric smart wallet, ...
(Date:1/22/2015)... 22, 2015 Infinisource has launched its new NXG series ... The G2 sets a higher standard for collecting attendance and ... solution. With plug-and-play installation, touch screen interface and seamless connection ... robust time collection solution for the small to mid-size employer. ...
(Date:12/19/2014)... DUBLIN , Dec. 18, 2014 Research and Markets ... of the "iPhone 5S Fingerprint Sensor - Apple/AuthenTec ... their offering. http://photos.prnewswire.com/prnh/20130307/600769 ... 2012, Apple introduced the fingerprint reading feature with the ...
Breaking Biology News(10 mins):Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3Infinisource's NXG series sets new time clock standard 2iPhone 5S Fingerprint Sensor - Apple/AuthenTec TMDR92 & Sapphire - Technology Report 2
... or fuel crop plants, could represent an abundant source ... International Journal of Automotive Technology and Management . ... and sal trees have almost as good a thermal ... carbon monoxide, waste hydrocarbons and NOx (nitrogen oxides). ...
... whole wheat bread a more appetizing aroma and taste may ... that appears in the bread, which nutritionists regard as more ... a new study in ACS, Journal of Agricultural and ... wheat bakery products more appealing to millions of people., Devin ...
... SANTA CRUZ, CA--The remarkable diversity of California,s plant life is ... 45 million years, according to a new study published in ... evolved in California, the rate at which plant lineages gave ... California than elsewhere, researchers found. Botanists have long recognized ...
Cached Biology News:Tree seeds offer potential for sustainable biofuels 2Low extinction rates made California a refuge for diverse plant species 2Low extinction rates made California a refuge for diverse plant species 3Low extinction rates made California a refuge for diverse plant species 4
(Date:1/22/2015)... 2015 Shimadzu Scientific Instruments today ... UV-visible spectrophotometer. Offering wavelength scanning from 190 to ... for applications in a variety of industries, including ... user-friendly UV-1280 enables intuitive operation, while the enhanced ...
(Date:1/22/2015)... laboratory information management systems market is a rapidly growing ... due to factors such as rising pressure to comply ... and increasing government support for adoption of HCIT solutions ... the market focus on technological advancements to further the ...
(Date:1/22/2015)... Dr. Greg Leyer of UAS Labs recently was ... Pre-Conference seminar on probiotics in San Diego, CA. , ... conference for health care professionals. This year’s pre-conference seminar was ... in health. Dr. Leyer spoke about the emerging topics and ...
(Date:1/22/2015)...   Cypher Genomics, Inc., the leading genome ... SQNM ), the leading molecular diagnostics company, today ... prenatal tests (NIPT). Through this agreement, Sequenom will ... advance analysis of clinically-relevant fetal sub-chromosomal variants detected ...
Breaking Biology Technology:Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 2Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 3Laboratory Information Management Systems Market is Expected to Reach $1,323.6 Million by 2019 - New Research Report by MarketsandMarkets 4Cypher Genomics and Sequenom Announce Development Agreement 2Cypher Genomics and Sequenom Announce Development Agreement 3Cypher Genomics and Sequenom Announce Development Agreement 4
... Sixth Annual Healthcare Unbound Conference & Exhibition, organized by ... coming together of consumer and healthcare technologies ... will take place at the Seattle Airport Marriott in ... include a diverse representation of the many business segments ...
... Nestle SA to select a new flavor ingredient ... and coffee whitener fields- Extension of discovery and ... collaborative research and license agreement with Campbell Soup ... filings for Bitter Blockers S0812 and S6821SAN DIEGO, ...
... Fla., May 7 Renewable fuels provider New Generation ... today announced that it has signed a contract with ... biofuel in an evaluation program for boiler applications in the ... of Baltimore has evaluated a non fossil fuel in its ...
Cached Biology Technology:Sixth Annual Healthcare Unbound Conference to Focus on Remote Monitoring, Home Telehealth & eHealth for Chronic Care Management & Wellness Promotion 2Sixth Annual Healthcare Unbound Conference to Focus on Remote Monitoring, Home Telehealth & eHealth for Chronic Care Management & Wellness Promotion 3SENOMYX ANNOUNCES FIRST QUARTER 2009 FINANCIAL RESULTS 2SENOMYX ANNOUNCES FIRST QUARTER 2009 FINANCIAL RESULTS 3SENOMYX ANNOUNCES FIRST QUARTER 2009 FINANCIAL RESULTS 4SENOMYX ANNOUNCES FIRST QUARTER 2009 FINANCIAL RESULTS 5SENOMYX ANNOUNCES FIRST QUARTER 2009 FINANCIAL RESULTS 6SENOMYX ANNOUNCES FIRST QUARTER 2009 FINANCIAL RESULTS 7SENOMYX ANNOUNCES FIRST QUARTER 2009 FINANCIAL RESULTS 8SENOMYX ANNOUNCES FIRST QUARTER 2009 FINANCIAL RESULTS 9SENOMYX ANNOUNCES FIRST QUARTER 2009 FINANCIAL RESULTS 10SENOMYX ANNOUNCES FIRST QUARTER 2009 FINANCIAL RESULTS 11City of Baltimore to Evaluate New Generation Biofuels for Use in Boiler Applications 2City of Baltimore to Evaluate New Generation Biofuels for Use in Boiler Applications 3
4-Hydroxy-3-nitrophenylacetyl hapten is conjugated to SSA (Sheep serum albumin) lysine through amide bonds. This product is homologous to NP-BSA....
Antibodies were affinity purified using epitopes specific to Alpha4 immobilized on solid support....
Collected from 8-12 week old sexually mature rats. Pricing: $100/unit for 1 - 10 units...
... host strains are K-12 derivatives that have ... and glutathione reductase (gor) genes, which greatly ... Studies have shown that expression in Origami(DE3) ... another host even though overall expression levels ...
Biology Products: