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UCLA scientists discover immune response to HIV differs, even in identical twins

"one size fits all" vaccine may not be possible.

"If the goal is to develop a vaccine, our findings suggestthis may not be so straightforward," said Dr. Otto Yang, associate professor of infectious diseases at the David Geffen School of Medicine at UCLA, and the study's lead researcher.

According to the UCLA researchers, the results of this study have broader implications, and could apply to other viruses such as cytomegalovirus (CMV), a herpes virus that causes opportunistic infections in immunosuppressed individuals, and hepatitis C, the latter being similar to HIV in both its changeable and chronic nature.

The study represented collaboration with other UCLA investigators and with Joseph Church of Children's Hospital Los Angeles and the Keck School of Medicine at the University of Southern California. Other researchers from the UCLA AIDS Institute and the David Geffen School of Medicine who contributed to the study are Ryan Kilpatrick, Ayub Ali, Yongzhi Geng, M. Scott Killian, Rachel Lubong Sabado, Hwee Ng, Jeffrey Suen, Yvonne Bryson, Beth D. Jamieson; and Christina M.R. Kitchen, associate professor of biostatistics, UCLA School of Public Health.


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Source:University of California - Los Angeles


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