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UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders

to therapies that target cell signaling pathways specific for cancer stem cells. These therapies hone in on what is broken in a cancer cell while leaving the healthy tissue intact. Several Jonsson Cancer Center researchers already are doing stem cell research in laboratories, and that work will be folded into the institute.

* Neurological disorders: UCLA researchers are studying many aspects of the roles that stem cells may play in healing neurological disorders, including stroke, spinal cord injury, brain tumors, multiple sclerosis and genetic diseases. Future studies will include investigation of stem cell biology and development, as well as therapeutic based research using adult and embryonic stem cells.

The Institute for Stem Cell Biology and Medicine is a collaboration of the David Geffen School of Medicine, UCLA's Jonsson Cancer Center, the Henry Samueli School of Engineering and Applied Science, and the UCLA College. Each collaborator brings leading-edge technologies to the table: integrated microfluidics to aid in cell isolation, microarrays and shape encoded particle approaches for gene expression analysis, proteomics using advanced mass spectroscopy, large-scale computational facilities for bioinformatics, and world-class multi modality imaging facilities for analysis of stem cell therapies in laboratory models and, ultimately, in patients enrolled in clinical trials.

"UCLA encourages strong collaborations between faculty in the life sciences and the health sciences," said Patricia O'Brien, executive dean of the UCLA College. "As biomedicine grows increasingly complex, new academic partnerships hold the key to discovery; this institute will create novel opportunities for research that spans many disciplines."


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Source:University of California - Los Angeles


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