Navigation Links
U of S Vaccine and Infectious Disease Organization team discovers key step in flu virus replication

As public health officials around the world keep a nervous eye on the spread of avian influenza, the University of Saskatchewan's Vaccine and Infectious Disease Organization (VIDO) has uncovered a key step in how the influenza virus causes infection.

Yan Zhou and her team have discovered how a crucial pathway that supports the influenza A virus's ability to reproduce itself is activated, a finding that could pave the way for new drugs and vaccines.

The paper will appear in the January 2007 issue of the Journal of General Virology and recently has been given advance on-line publication.

"The work we are doing will be applicable to all influenza viruses, including influenza A virus subtype H5N1," said VIDO Director Lorne Babiuk.

Zhou says that although years of research remain to be done, this work provides novel insights for developing live vaccines and antiviral drugs for influenza epidemics and pandemics. A provisional patent has been filed on the findings.

"Given the health, economic and social consequences of influenza epidemics, the work of Dr. Zhou and her team demonstrates the importance of building influenza research capacity in Canada," said Dr. Bhagirath Singh, Scientific Director of the CIHR Institute of Infection and Immunity.

"Their research findings may help to develop new influenza treatments and prevent the disease, as well as add to global pandemic preparedness research."

To survive, the influenza virus hijacks the host animal or human's cellular machinery and forces it to make more copies of the virus. The researchers believe that the cellular events involved in this process are an excellent target for interventions against influenza.

The study revealed novel characteristics of a protein, called NS1, that activates a key pathway in the virus's reproduction. This information will help the researchers learn how to create harmless influenza viruses that can be used as live
'"/>

Source:mediarelations@cihr-irsc.gc.ca


Page: 1 2

Related biology news :

1. FDA Approves Human Hookworm Vaccine for Phase I Safety Trials
2. Live Recombinant Adenovirus Vaccine Technique Explored
3. Gene Vaccine Protects Mice Against Development Of Her2/neu Breast Cancer
4. NIAID Initiates Trial of Experimental Avian Flu Vaccine
5. Study Models Impact Of Anthrax Vaccine
6. New Insights Into HIV Immunity Suggest Alternative Approach to Vaccines
7. Pathogen-Mimicking Vaccine As Strategy For Cancer Therapy
8. EuroVacc 02 HIV Vaccine Trial Begins
9. Active Vaccine Prevents Mice From Developing Prion Disease
10. New Vaccine To Be Used For First Time In Polio Outbreak Response
11. Boosting The BCG Vaccine To Beat Tuberculosis
Post Your Comments:
(Date:11/18/2008)...AM, Ala. The University of Alabama at Birmingham ...utics (CERTs) has won a $2.2 million federal grant...of medicines called biologics. These are genetical...tem of patients who have rheumatoid arthritis, Cro...ders. , The award will allow the UAB CERTs to pi...
(Date:11/18/2008)...erlands Organisation for Scientific Research (NWO)...ences (KNAW) have joined forces with colleagues in...nt Scientific Thematic Research Programme (JSTP). ... work together on developing bilateral cooperation...O and the Academy launched the joint research prog...
(Date:11/17/2008)..., Md. (Nov. 18, 2008) − A new study confirms... in the production of neural stem cells in the hip...s happens because exercise restores a brain chemic... new stem cells. , Neural stem cells and progeni...erve cells which have different functions, a proce...
(Date:11/17/2008)... it,s called, this new small satellite mission spo...t,s designed to help solve the mystery of the most...atmosphere: TGFs, or terrestrial gamma-ray flashes...ission is the second project under the new NSF Cub...of a loaf of bread, consists of three cubes attach...
Breaking Biology News(10 mins):Musculoskeletal center wins $2.2 million for drug safety 2NWO and Academy launch research program with China 2Exercise increases brain growth factor and receptors, prevents stem cell drop in middle age 2Exercise increases brain growth factor and receptors, prevents stem cell drop in middle age 3Small satellite takes on large thunderstorms 23 drug combination extremely promising as first line therapy for multiple myeloma 8054 13 drug combination extremely promising as first line therapy for multiple myeloma 8054 2Exercise testing may help predict seriousness of mitral regurgitation 8053 1Exercise testing may help predict seriousness of mitral regurgitation 8053 2Scat sniffing dogs detecting rare California carnivores 1545 1Scat sniffing dogs detecting rare California carnivores 1545 2Highmark Presents Work on MRSA Prevention at National Health Care Quality Conference 1042 1Highmark Presents Work on MRSA Prevention at National Health Care Quality Conference 1042 2
...t for the survival of many types of cells stimulat...?critical brain cells that connect the cerebral co...uron diseases like amyotrophic lateral sclerosis (...6 issue of Nature Neuroscience, two investigators ...Harvard Stem Cell Institute describe how insulin-l...
...sm" can counteract the effects of tumor-promoting ... by investigators at the University of Pennsylvani...earchers discovered that Srcasm acts like a brake ...growth caused by a family of proteins called Src k...nal of Biological Chemistry, suggests a target for...
... stop producing special proteins that minimize env...nge of intense environmental conditions in one of ...ound that adult midges (Belgica antarctica) lose t...ve heat-shock proteins. Instead, like most animals...ey are stressed. The discovery currently appears i...
...king young women to participate in the first U.S. ...d to prevent herpes and HIV infection. , If it is ...dministration, the gel would be an important weapo...women to protect themselves from infection rather ..., "The significance of the gel is that it potentia...
Other Biology News:Growth factor stimulates rapid extension of key motor neurons in brain 2Signal protein shows promise for blocking tumor promoters in skin cells 2Unique gene regulation gives chilly bugs survival advantage at bottom of the world 2Unique gene regulation gives chilly bugs survival advantage at bottom of the world 3UCSF study will test new vaginal microbicide for herpes and HIV 2UCSF study will test new vaginal microbicide for herpes and HIV 3
(Date:11/17/2008)... ExCeltrix Preliminary Oncology Da... San Diego, CA (PRWEB) November 17, 2008 -...nerative medicine company developing solutions bas...ddressed attendees at the 6th Annual Commercial Tr...ing place November 17-18, 2008 in London. , , ,Dr....
(Date:11/17/2008)... New Company Combines Talent and E...through Programmability and Performance Technology...gh Performance Computing (HPC) Industry. , ...2008 -- A revolutionary solution to the high-perfo... performance and programmability barriers launched...
(Date:11/15/2008)... Gowling Lafleur Henderson LLP, on... FileTrail RFID solution for file tracking and phy...FileTrail Web Services to integrate physical recor...ent System, and distribute functionality to the Fi...an Jose, CA (PRWEB) November 17, 2008 -- Gowling L...
(Date:11/14/2008)...GE, Mass. Researchers at the Harvard School of En...rated experimentally and theoretically that the su... a periodic array can have considerably narrower s...rticles. Further, as the optical fields are signif...od could improve the sensitivity of detecting mole...
Breaking Biology Technology:Dr. Gail Naughton Speaks on Histogen's Business Plan and the Rise of Bioaesthetic Medicine during Commercial Translation of Regenerative Medicine 2Dr. Gail Naughton Speaks on Histogen's Business Plan and the Rise of Bioaesthetic Medicine during Commercial Translation of Regenerative Medicine 3Convey Computer™ Corporation Launches World's First Hybrid-Core Computer at SC08 Conference 2Convey Computer™ Corporation Launches World's First Hybrid-Core Computer at SC08 Conference 3Convey Computer™ Corporation Launches World's First Hybrid-Core Computer at SC08 Conference 4Convey Computer™ Corporation Launches World's First Hybrid-Core Computer at SC08 Conference 5Gowlings Adopts RFID and Unifies Practice Management 2Gowlings Adopts RFID and Unifies Practice Management 3Gowlings Adopts RFID and Unifies Practice Management 4Surface plasmon resonances of metal nanoparticles in array can have narrower spectral widths 2
...ok a look at the results of the National Institut...time, we saw that the Midwest had two states in th...ve states in the top 20 states. I promised to circ...ding universities for 2005 to see how the Midwest ... U.S. Department of Health and Human Services an...
...ate Senator Ted Kanavas , R-Brookfield, continues ...eral law to suspend taxation on Internet access, b...e said the state is in compliance with the law. ,...own as the Internet Nondiscrimination Act of 2004....ect Internet users from being taxed for simply log...
...onsin is slowly getting over its shyness about ask...sin and Midwestern small business executives is le... Small Business Innovation Research-Small Business...waukee City Center Hotel . , ,The two congressiona...er small business innovation, and the other (STTR)...
...ould consider dayparting tactics and strategies th...gn. , ,Until recently, Google AdWords tactics were...creative, and geography. However, when Google bega...eters with another way to control AdWord spending ...dayparting strategies. , ,Ad scheduling (aka "day...
Other Biology Technology:Midwest colleges strong contenders for NIH funds 2Midwest colleges strong contenders for NIH funds 3Midwest colleges strong contenders for NIH funds 4Midwest colleges strong contenders for NIH funds 5Kanavas rips Doyle for taxing Internet 2Wisconsin firms urged to pursue federal SBIR dollars 2Wisconsin firms urged to pursue federal SBIR dollars 3Getting the most from Google dayparts 2Getting the most from Google dayparts 3
Request Info
QML offers standard and customized paraffin embedded tissue blocks.
This service involves the optimization of immunostaining. The optimization includes titration of the primary antibody, selection and optimization of secondary reagents (e.g. Alk. Phos., HRP, fluores
...USDA Research Registered OLAW Assured AAALAC Accre...ALAS Certified Technicians Documentation GLP Pro...uest Focus CRP is your one stop shopping point f...ffer free project consultation, free peptide seque...
Biology Products: