Navigation Links
U of MN uses robotic surgery techniques in cardiac cell therapy research

Researchers at the University of Minnesota were successful in using robotic surgery to deliver stem cell treatment to damaged heart tissue in pigs.

Using minimally invasive robotic surgery equipment, researchers injected the stem cells into the damaged hearts. The cells were "labeled" with iron particles so that researchers would be able to see if they engrafted in the pig hearts.

The cells were successfully transplanted in six of seven cases. Subsequent MRI studies showed that the cells took hold in the heart and function improved.

The team used a combination of skeletal myoblasts, or cells that give rise to muscle, and bone-marrow derived cells. Both cell types have been shown to improve the development of new blood vessels and to improve function of injured heart muscle. Both are in human clinical trials as well.

The research is published in the current issue of the Journal of Thoracic and Cardiovascular Surgery.

Once more animal studies are completed, the technique could be applied in human clinical trials.

"In people with heart failure, open surgery can be risky; finding a minimally invasive technique to deliver cell therapy to the damaged cardiac tissue would reduce the risk to patients," said Doris A. Taylor, Ph.D., professor of Physiology, holder of the Medtronic Bakken Chair in Cardiovascular Repair, and co-leader of the study.

The minimally invasive approach would offer several benefits for people in heart failure, Taylor said. It is less dangerous to the patient. It can be done while the heart is still beating, and requires less time under anesthesia. It also offers surgeons a magnified view of the heart and allows them to target the cell infusion more precisely.

Harald Ott, M.D., co-leader of this study, now a surgery resident at Massachusetts General Hospital in Boston, pointed out, "Currently these types of cell therapies, in which stem cells are injected into damaged hearts, are only available to people who are enrolled in clinical research trials."

Skeletal and bone marrow cells that are injected into damaged heart tissue have been shown to improve function in the left ventricle, the chamber of the heart that pumps blood into the aorta, the main artery through which oxygen-rich blood flows from the heart to the body.

Taylor said more research needs to be done to determine which types of cells are most beneficial to infuse into damaged hearts, as well as if the minimally invasive technique can deliver similar results as traditional open surgery. "But that is what keeps us busy," she added," finding the best treatment for patients with heart disease."


'"/>

Source:University of Minnesota


Related biology news :

1. 3-D ultrasound scanner could guide robotic surgeries
2. Rare surgery performed to remove pancreas, prevent diabetes
3. Scalpel-free surgery could reduce risk of HIV and hepatitis exposure for health care workers
4. 3D ultrasound device poised to advance minimally invasive surgery
5. For one Stanford doctor, the beat goes on during open-heart surgery
6. Unique equine cataract surgery offered on routine basis
7. Cheaper and simpler keyhole surgery
8. Robot assisted surgery more accurate than conventional surgery
9. New biologic treatment for tennis elbow may replace surgery for chronic sufferers
10. Jefferson scientists find high glucose before surgery raises risk of dangerous complications
11. Successful lung cancer surgery not enough to break nicotine dependence in many smokers
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/9/2016)... Vigilant Solutions announces today that an agency used its Vigilant ... in a difficult homicide case. The agency then used Vigilant,s ... vehicle. Due to the ongoing investigation, the agency name and ... agency,s request. --> --> ... deceased at an intersection here in the City. He had ...
(Date:2/4/2016)... , Feb. 4, 2016 The field ... one of the most popular hubs of the ... and other huge studies of human microbiota, have ... few years, the microbiome space has literally exploded ... research. This report focuses on biomedical aspects ...
(Date:2/3/2016)... , Feb. 3, 2016 Vigilant Solutions announces ... Department in Missouri solved two ... reader (LPR) data from Vigilant Solutions. Brian ... in which the victim was walking out of a convenience store and witnessed ... next to his vehicle, striking his vehicle and leaving ...
Breaking Biology News(10 mins):
(Date:2/11/2016)... Germany and GERMANTOWN, ... QGEN ; Frankfurt Prime Standard: QIA) today announced ... RNA Panels for gene expression profiling, expanding QIAGEN,s portfolio ... The panels enable researchers to select from over 20,000 ... and discover interactions between genes, cellular phenotypes and disease ...
(Date:2/11/2016)... , Feb. 11, 2016  Spectra BioPharma Selling Solutions ... that provides biopharma companies the experience, expertise, operational ... deploy outsourced sales teams. Created in concert with ... both the strategic and tactical needs of its ... solutions through both personal and non-personal promotion. ...
(Date:2/11/2016)... (PRWEB) , ... February 11, ... ... business-to-business publication dedicated to delivering cutting-edge information focused on the development and ... Sciences to become a premier sponsor of the 2016 BioProcess International Awards ...
(Date:2/11/2016)... , February 11, 2016 ... ("PositiveID" or "Company") (OTCQB: PSID), a life sciences ... that its Thermomedics subsidiary, which markets the Caregiver® ... growth plan in January 2016, including entering into ... sequential monthly sales growth, and establishing several near-term ...
Breaking Biology Technology: