Navigation Links
U of MN researchers turn cord blood into lung cells

Researchers at the University of Minnesota have, for the first time, coaxed umbilical cord blood stem cells to differentiate into a type of lung cell.

The cord blood cells differentiated into a type of lung cell called type II alveolar cells. These cells are responsible for secreting surfactant, a substance which allows the air sacs in the lungs to remain open, allowing air to move in and out of the sacs. The cells are also responsible for helping to repair the airway after injury.

"In the future, we may be able to examine cord blood from babies who have lung diseases, such as cystic fibrosis, to do more research to understand how these diseases evolve as well as to develop better medical treatments," said David McKenna, M.D., assistant professor of lab medicine and pathology and medical director of the Clinical Cell Therapy Lab at the University of Minnesota Medical Center, Fairview.

The research paper is currently available online, and will be published in the Nov. 7, 2006, issue of the journal Cytotherapy.

Type II alveolar cells develop late in fetal development, which is why some premature babies are born with underdeveloped lungs. The cells and the air sacs as a whole continue to mature and develop through a child's first few years of life.

Now the researchers will try to better characterize the cells, so that in the future, the cells could be used as a research tool to better understand lung development and disease. The cells may also be useful as a way to test potential new drugs.

To differentiate the lung cells from the cord blood, McKenna and his team first derived the Multi-Lineage Progenitor CellTM (MLPCTM) from umbilical cord blood. This stem cell, which was first isolated and characterized by BioE®, Inc., St. Paul, is a precursor cell that can be expanded in culture, then differentiated into different types of tissue representative of all three embryonic lineages, endoderm, m
'"/>

Source:University of Minnesota


Page: 1 2

Related biology news :

1. NYU researchers simulate molecular biological clock
2. Vital step in cellular migration described by UCSD medical researchers
3. ASU researchers finds novel chemistry at work to provide parrots vibrant red colors
4. UCSD researchers maintain stem cells without contaminated animal feeder layers
5. Why do insects stop breathing? To avoid damage from too much oxygen, say researchers
6. New protein discovered by Hebrew University researchers
7. First real-time view of developing neurons reveals surprises, say Stanford researchers
8. Agilent Technologies releases automated literature search tool for biology researchers
9. Self-assembled nano-sized probes allow Penn researchers to see tumors through flesh and skin
10. Yale researchers identify molecule for detecting parasitic infection in humans
11. US life expectancy about to decline, researchers say
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: researchers turn cord blood into lung cells

(Date:9/16/2014)... Spanish . CRG ... the Journal of Cell Biology describes how Topo ... division , At this very moment thousands of our body,s ... which the body repairs damaged tissues and regenerates others like ... as "mitosis", during which the cell duplicates its genetic material ...
(Date:9/16/2014)... vital functions in an organism. For example, they ... and control immune system responses. Researchers established some ... of each other, but instead form complex networks. ... find many similarities with online social networks," says ... Systems Biology. "Some proteins are good networkers that ...
(Date:9/16/2014)... , Sept. 16, 2014 As open ... make important decisions about their 2015 benefits. According to ... health solutions business of Aon plc (NYSE: ... take a more proactive role in managing their health ... than ever for individuals to understand how they can ...
Breaking Biology News(10 mins):Unraveling cell division 2Unraveling cell division 3Good networkers make prime targets 2Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 2Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 3Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 4Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 5Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 6Aon Hewitt Provides Tips to Help Workers Prepare for the Upcoming Open Enrollment Season 7
... , EAST LANSING, Mich. Bacteria infections most of ... world and not malaria are the leading cause of ... new Michigan State University project based in Nigeria and funded ... diseases by collecting local data on the ailments, spurring vaccine ...
... European Molecular Biology Laboratory (EMBL) in Monterotondo, is one ... honoured with a Howard Hughes Medical Institute (HHMI) International ... for five years, is designed to give a boost ... United States. The award recognises the potential of Sotillo,s ...
... concern that excessive levels of fructose may pose a great health ... researchers at the University of Colorado School of Medicine, along with ... if two common sweeteners in western diets differ in their effects ... The study, recently published in the journal Metabolism , took ...
Cached Biology News:$5.8 million Gates grant targets child-killing bacteria diseases in Africa 2CU School of Medicine researchers look at effects of 2 common sweeteners on the body 2
(Date:9/16/2014)... cell phones to cars and flashlights, batteries play ... technology companies constantly are seeking ways to improve ... time using a water-based solution, researchers at the ... more efficient nuclear battery that could be used ... source in automobiles and also in complicated applications ...
(Date:9/16/2014)... BlueInGreen® , a water ... for delivering dissolved gases into liquids, announced the ... a manufacturer’s representative firm to its sales network. ... municipal water and wastewater applications in the Canadian ... founded in 1992 and serves Quebec and Ontario ...
(Date:9/16/2014)... MILLBROOK, N.Y. , Sept. 16, 2014  Donald Fresne, ... the appointment of Stephan Vagner , PhD to its ... the University of Toulouse, France , performed ... Germany , and at Inserm, the French institute of ... Inserm and works both at the Curie Institute, Orsay, ...
(Date:9/16/2014)... , Sept. 16, 2014  The Council ... entrepreneurial support organization in the country, today released ... Report . It showed that ... North Carolina startups in the technology, ... more global investment from a variety of sources. Significant ...
Breaking Biology Technology:BlueInGreen® Expands into Canada – Signs Representative Agreement with H2Flow Equipment Inc. 2New Appointment to the Scientific Advisory Committee at Egenix, Inc. 2CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 2CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 3CED's Mid-Year Update to its Innovators Report Shows NC Startups Attracting Investment From Across the Globe with Several High-Profile Investment Deals, IPOs and Acquisitions Signaling Strength of Entrepreneurial Sector 4
... led by Governor Doyle and organized by Forward Wisconsin ... industrys leading conference with goals to establish new partnerships, ... community and to let others know that Wisconsin has ... group, the delegation met its objectives in spite of ...
... Medical Systems, a unit of General Electric Company, announced ... Food and Drug Administration to begin marketing its new ... Signa EXCITE 3.0T combines the increased speed and higher ... of imaging capabilities found on premium 1.5 Tesla systems. ...
... Insurance. Motorcycles? Computerworld has just released their ... 2003, and five Wisconsin companies have placed in the ... Inc. of Milwaukee. , ,This years list, with ... employees perspectives of working conditions and employment benefits. According ...
Cached Biology Technology:On site at BIO 2003 2On site at BIO 2003 3On site at BIO 2003 4On site at BIO 2003 5GE Medical Systems Receives FDA Clearance for New MRI System 2Wisconsin Companies Ranked Top in Nation in IT 2Wisconsin Companies Ranked Top in Nation in IT 3Wisconsin Companies Ranked Top in Nation in IT 4
Rad 50 Immunogen: c-terminal mRad 50 (604 amino acids). Storage: 4 C...
...
... Kit Includes: Sufficient library for ... x 10^9 independent sequences, -28 gIII ... DNA sequencing, -96 gIII Sequencing Primer ... Host E. coli strain ER2738, Control ...
... The CHEMICON Re-Blot Western Blot Recycling ... antibodies from Western blots that have ... iodine or other isotopes. It is ... (TMB, DAB, 4-chloronapthol, etc.), as it ...
Biology Products: