Navigation Links
U of M study examines kidney stone prevention in astronauts

As the space shuttle Discovery prepares to launch on July 1, researchers at the University of Minnesota have identified a way for astronauts to reduce their risk of developing kidney stones while in space.

Astronauts lose calcium in their bones and strength in their muscles while in space because of the zero-gravity environment. This calcium can end up in their kidneys, putting them at risk for developing kidney stones.

At least 14 American crew members have developed kidney stones in the last 5 years, and as missions become longer, the number is likely to grow. While astronauts have exercised in space to attempt to combat bone loss, the lack of gravity makes it difficult to achieve enough resistance to maintain their pre-flight fitness levels.

"This becomes a real health concern, as the time astronauts spend in space and living in the space station is extended," said Manoj Monga, M.D., professor of urologic surgery and lead investigator. The study will be published in the July 2006 print issue of the Journal of Urology and is available online now.

Kidney stones are mineral deposits in the kidneys that can travel through the urinary tract, causing intense pain. One of the most common types of kidney stones is caused by the buildup of calcium oxalate.

Researchers studied the effects of exercise in pairs of identical twins, since a portion of a person's risk for developing kidney stones is genetic. The study participants had no history of kidney stones and were placed on standardized diets.

The twins were put on bed rest on a tilted bed that positioned their head lower than their feet to simulate low gravity for 30 days. One twin per pair was randomly selected to exercise (while still reclining) in a chamber that put negative pressure, or resistance on their lower body, and the other twin served as a non-exercising control. The pressure in the chamber was roughly equivalent to what a person would experience running on Earth.

Monga found that the non-exercising study participants had higher levels of urinary calcium than the exercising group, and thus had a greater risk of developing kidney stones. Additionally, many astronauts do not drink enough water while in space, so their urine output is lower, and the food they consume is higher in sodium, which also increases the risk for kidney stone development.

"In combination with hydration therapy, exercise in a machine that simulates gravity could reduce the astronaut's risk of developing kidney stones, a condition that could be particularly painful and lead to an aborted mission," Monga said.


'"/>

Source:University of Minnesota


Related biology news :

1. Bioartificial kidney under study at MCG
2. W.M. Keck Foundation funds study of friendly microbes
3. Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
4. Genome-wide mouse study yields link to human leukemia
5. Clam embryo study shows pollutant mixture adversely affects nerve cell development
6. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
7. Same mutation aided evolution in many fish species, Stanford study finds
8. Sequencing of marine bacterium will help study of cell communication
9. Genetically modified rice in China benefits farmers health, study finds
10. A new study examines how shared pathogens affect host populations
11. NYU study reveals how brains immune system fights viral encephalitis
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/22/2016)... ANGELES , June 22, 2016 /PRNewswire/ ... identity management and verification solutions, has partnered ... edge software solutions for Visitor Management, Self-Service ... provides products that add functional enhancements ... partnership provides corporations and venues with an ...
(Date:6/21/2016)... , June 21, 2016 NuData Security announced ... new role of principal product architect and that ... director of customer development. Both will report directly ... officer. The moves reflect NuData,s strategic growth in ... to high customer demand and customer focus values. ...
(Date:6/16/2016)... FRANCISCO , June 16, 2016 ... size is expected to reach USD 1.83 ... by Grand View Research, Inc. Technological proliferation and ... banking applications are expected to drive the market ... ) , The development of advanced ...
Breaking Biology News(10 mins):
(Date:6/23/2016)... (PRWEB) , ... June 23, 2016 , ... ... is pleased to announce the launch of their brand, UP4™ Probiotics, into Target ... over 35 years, is proud to add Target to its list of well-respected ...
(Date:6/23/2016)... , June 23, 2016 A person commits a ... crime scene to track the criminal down. An ... Food and Drug Administration (FDA) uses DNA evidence to track ... Sound far-fetched? It,s not. The FDA has increasingly ... support investigations of foodborne illnesses. Put as simply as possible, ...
(Date:6/23/2016)... MONICA, Calif. , June 23, 2016  The Prostate Cancer Foundation ... pioneer increasingly precise treatments and faster cures for prostate cancer. Members of the ... institutions across 15 countries. Read More About the Class ... ... ...
(Date:6/23/2016)... ... ... Supplyframe, the Industry Network for electronics hardware design and ... in Pasadena, Calif., the Design Lab’s mission is to bring together inventors and ... brought to market. , The Design Lab is Supplyframe’s physical representation of one ...
Breaking Biology Technology: