Navigation Links
U of M study examines kidney stone prevention in astronauts

As the space shuttle Discovery prepares to launch on July 1, researchers at the University of Minnesota have identified a way for astronauts to reduce their risk of developing kidney stones while in space.

Astronauts lose calcium in their bones and strength in their muscles while in space because of the zero-gravity environment. This calcium can end up in their kidneys, putting them at risk for developing kidney stones.

At least 14 American crew members have developed kidney stones in the last 5 years, and as missions become longer, the number is likely to grow. While astronauts have exercised in space to attempt to combat bone loss, the lack of gravity makes it difficult to achieve enough resistance to maintain their pre-flight fitness levels.

"This becomes a real health concern, as the time astronauts spend in space and living in the space station is extended," said Manoj Monga, M.D., professor of urologic surgery and lead investigator. The study will be published in the July 2006 print issue of the Journal of Urology and is available online now.

Kidney stones are mineral deposits in the kidneys that can travel through the urinary tract, causing intense pain. One of the most common types of kidney stones is caused by the buildup of calcium oxalate.

Researchers studied the effects of exercise in pairs of identical twins, since a portion of a person's risk for developing kidney stones is genetic. The study participants had no history of kidney stones and were placed on standardized diets.

The twins were put on bed rest on a tilted bed that positioned their head lower than their feet to simulate low gravity for 30 days. One twin per pair was randomly selected to exercise (while still reclining) in a chamber that put negative pressure, or resistance on their lower body, and the other twin served as a non-exercising control. The pressure in the chamber was roughly equivalent to what a person would experience running on Earth.

Monga found that the non-exercising study participants had higher levels of urinary calcium than the exercising group, and thus had a greater risk of developing kidney stones. Additionally, many astronauts do not drink enough water while in space, so their urine output is lower, and the food they consume is higher in sodium, which also increases the risk for kidney stone development.

"In combination with hydration therapy, exercise in a machine that simulates gravity could reduce the astronaut's risk of developing kidney stones, a condition that could be particularly painful and lead to an aborted mission," Monga said.


'"/>

Source:University of Minnesota


Related biology news :

1. Bioartificial kidney under study at MCG
2. W.M. Keck Foundation funds study of friendly microbes
3. Yellowstone microbes fueled by hydrogen, according to U. of Colorado study
4. Genome-wide mouse study yields link to human leukemia
5. Clam embryo study shows pollutant mixture adversely affects nerve cell development
6. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
7. Same mutation aided evolution in many fish species, Stanford study finds
8. Sequencing of marine bacterium will help study of cell communication
9. Genetically modified rice in China benefits farmers health, study finds
10. A new study examines how shared pathogens affect host populations
11. NYU study reveals how brains immune system fights viral encephalitis
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:8/15/2017)... Aug. 15 2017   ivWatch LLC , a medical device ... therapy, today announced receipt of its ISO 13485 Certification, the global ... International Organization for Standardization (ISO®). ... ivWatch Model 400 Continuous Monitoring device for the early detection of ... "This is an important milestone ...
(Date:6/30/2017)... , June 30, 2017 Today, American ... and supplier of face and eye tracking software, ... Product provider program. "Artificial intelligence ... way to monitor a driver,s attentiveness levels while ... being able to detect fatigue and prevent potential ...
(Date:6/14/2017)... June 15, 2017  IBM (NYSE: IBM ) is introducing ... event dedicated to developing collaboration between startups and global businesses, ... 15-17. During the event, nine startups will showcase the solutions ... various industries. France ... market, with a 30 percent increase in the number of ...
Breaking Biology News(10 mins):
(Date:10/11/2017)... Alto, CA, USA (PRWEB) , ... October 11, 2017 , ... ... set to take place on 7th and 8th June 2018 in San Francisco, CA. ... policy influencers as well as several distinguished CEOs, board directors and government officials from ...
(Date:10/11/2017)... ... , ... Disappearing forests and increased emissions are the main causes of the ... Especially those living in larger cities are affected by air pollution related diseases. , ... pollution-affected countries globally - decided to take action. , “I knew I had to ...
(Date:10/10/2017)... Los Angeles, CA (PRWEB) , ... ... ... Pharmaceuticals, Inc., a development-stage cancer-focused pharmaceutical company advancing targeted antibody-drug conjugate (ADC) ... all uses of targeted HPLN (Hybrid Polymerized Liposomal Nanoparticle), a technology developed ...
(Date:10/10/2017)... SANTA CRUZ, Calif. , Oct. 10, 2017 /PRNewswire/ ... SBIR grant from the NIH to develop RealSeq®-SC (Single ... preparation kit for profiling small RNAs (including microRNAs) from ... Cell Analysis Program highlights the need to accelerate development ... "New techniques for ...
Breaking Biology Technology: