Navigation Links
Tissue regeneration operates differently than expected

Max Planck researchers in Bad Nauheim discover the mechanism by which adult stem cells are integrated into skeletal or heart muscle tissue.
There is disagreement, however, about the mechanism on which repair processes are based. Scientists from the Max Planck Institute for Heart and Lung Research in Bad Nauheim, Germany, in co-operation with colleagues from Martin Luther University in Halle-Wittenberg, have now shown that skeletal muscle tissue can fuse with adult stem cells, via a mechanism based on the participation of mediators which are generally involved in immune cell activation.

Although being unable to transdifferentiate into completely functional muscle cells, they are integrated into the tissue complex by fusing with differentiated tissue cells. In contrast, in the heart muscle tissue the mechanism seems to be different from this. The scientists in Bad Nauheim conclude from their study that adult stem cells are involved in tissue repair processes in a paracrine way by delivering mediating factors rather than by simply becoming components of the regenerating organ. (Genes & Development, August 2005).

Stem cells are fully unspecialised cells which can develop into all kinds of cell types. Embryonic stem cells provide the origin of a developing organ, during the growth of an embryo. For example, mesenchymal cells ?stem cells from embryonic connective tissue ?transform themselves during embryogenesis into muscle cells, under the influence of certain growth factors.

Other stem cells ?adult stem cells ?play an important role throughout an organism's life. For example, bone marrow stem cells provide for the replenishment of short-lived blood cells. Adult stem cells can be found locally in various tissues and organs, and we have presumed that they are participating in the repair and maintenance of organ functions.

The controversial idea is that adult stem cells have the potential for transdifferentiation; in other words, th
'"/>

Source:Max-Planck-Gesellschaft


Page: 1 2 3

Related biology news :

1. Stem Cell Research Shows Potential for Replacing Tissue Damaged in Heart Attacks
2. Govt Creates Gene Database of Normal Human Tissues
3. Chronic Sinus Infection Thought To Be Tissue Issue, Mayo Clinic Scientists Show Its Snot
4. Tissue engineering for craniofacial reconstruction
5. Tissue engineered scaffolding allows reproduction of cartilage tissue
6. New component of the brakes on nerve regeneration found
7. Researchers feed tiny pills of RNA to planarians to identify genes essential for regeneration
8. New understanding of regeneration gained by Forsyth scientists
9. Protein-coated dental implants could improve bone regeneration
10. Rescuing injured hearts by enhancing regeneration
11. Key to zebrafish heart regeneration uncovered
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Tissue regeneration operates differently than expected

(Date:3/24/2015)... , Mar. 24, 2015 Research and Markets ... the "Global Iris Recognition Market 2015-2019" report ... Global Iris Recognition market to grow at a CAGR ... This report covers the present scenario and the growth ... period 2015-2019. To calculate the market size, the report ...
(Date:3/24/2015)... , March 24, 2015   NexID Biometrics ... with critical security-authentication needs, today announced the beginning of ... (FFD) solution. The company, based in ... at the three-day Connect:ID Expo, which began here today ... NexID said version 2.0 of its SDK boosts the ...
(Date:3/23/2015)... BOSTON, Mass , March 23, 2015 SoundView ... shipment of NXT-ID,s (NASDAQ: NXTD ) Wocket smart wallet. SoundView ... world user feedback on their experience with the Wocket in ... experience at CVS, Whole Foods and other retailers, making both ... Kris Tuttle also says, "If the company meets ...
Breaking Biology News(10 mins):Global Iris Recognition Market 2015-2019 with 3M Cogent, Bioenable Technologies, Cross Match Technology, Iris ID Systems & Safran Dominating 2NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4
... 2013 The report "Maritime Security Market ... and Tracking (Underwater, Video, AIS, LRIT, Imaging); Detectors; SCADA; ... - 2018)", defines and segments the global Maritime Security ... forecast of revenues. It also identifies drivers and restraints ...
... , November 26, 2013 L,appareil et ... extérieur dans plus de 30 pays Wonder Technology ... vient de lancer Trax, un traceur GPS pour enfants ... et son application permettent aux utilisateurs de localiser leurs ...
... sunlight. While some wavelengths are indispensable to them for ... plants are equipped to detect these highly toxic rays ... Ulm, Professor at the Faculty of Sciences at the ... plant which acclimatises constitutively, regardless of the level of ...
Cached Biology News:Maritime Security Market Worth $19.48 Billion by 2018 2Maritime Security Market Worth $19.48 Billion by 2018 3Suivez vos enfants et vos animaux domestiques grâce à TRAX, le nouveau traceur GPS intelligent 2Suivez vos enfants et vos animaux domestiques grâce à TRAX, le nouveau traceur GPS intelligent 3A plant which acclimatizes with no exterior influence 2
(Date:5/4/2015)... , May 4, 2015  Traverse Biosciences ... cooperative research and development agreement (CRADA) with Aratana ... the development of TRB-N0224 for the treatment and ... dogs and cats.  Traverse Biosciences has also granted ... the treatment and control of periodontal disease in ...
(Date:5/4/2015)... , May 4, 2015 /PRNewswire/ - The ... partners are pleased to announce the formation of ... on developing treatments for cancer that harness the ... represents a unique collaboration between the Children,s Hospital ... Research Institute, McMaster University, the Ontario Institute for ...
(Date:5/4/2015)... Boston, MA (PRWEB) May 04, 2015 ... solutions for drug discovery and life science research, ... 5.0 , the latest version of its enterprise ... for biopharma R&D enables more efficient discovery and ... holistic approach to integrate and address protein optimization ...
(Date:5/4/2015)...  Soligenix, Inc. (OTCQB: SNGX) (Soligenix or the Company), ... medical needs in the areas of inflammation, oncology and ... data from three of its biodefense programs at the ... on May 12-14, 2015 to be held at the ... St. Louis MO 63101. ...
Breaking Biology Technology:Traverse Biosciences Executes Agreement with Aratana Therapeutics to Advance Development of TRB-N0224 for the Treatment and Control of Periodontal Disease in Pets 2Traverse Biosciences Executes Agreement with Aratana Therapeutics to Advance Development of TRB-N0224 for the Treatment and Control of Periodontal Disease in Pets 3Traverse Biosciences Executes Agreement with Aratana Therapeutics to Advance Development of TRB-N0224 for the Treatment and Control of Periodontal Disease in Pets 4Turnstone Biologics Inc. to accelerate clinical and commercial translation of cancer immunotherapies 2Turnstone Biologics Inc. to accelerate clinical and commercial translation of cancer immunotherapies 3Genedata Biologics 5.0 – Antibody Engineering and Developability Assessment Advances 2Genedata Biologics 5.0 – Antibody Engineering and Developability Assessment Advances 3Genedata Biologics 5.0 – Antibody Engineering and Developability Assessment Advances 4Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 2Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 3Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 4Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 5Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 6Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 7Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 8Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 9Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 10Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 11Soligenix Announces Presentation and Poster at the 2015 Chemical and Biological Defense Science and Technology Conference in St. Louis, MO 12
... elected mayor of Colorados largest city, businessman John Hickenlooper invited ... was to ceremoniously bury the hatchet of intra-regional rivalry and ... metropolitan area, or not at all. , ,Every suburban ... a near-unanimous effort to pass a $4.7-billion mass transit initiative ...
... data quality firm Firstlogic for about $69 million ... second quarter. , ,Firstlogic is a privately held firm that ... sure their data is as correct as they need to ... call centers, web sites, customer relationship management systems, and business ...
... settled with a Belgian company that sued last September ... virus genotyping technology from Innogenetics, for undisclosed financial terms. ... Aril 2004 Third Wave forged a deal under which ... line of products in Europe. It was Third Wave's ...
Cached Biology Technology:Economic collaboration in Denver sets tall goal for Wisconsin 2Economic collaboration in Denver sets tall goal for Wisconsin 3
Anti-ACTH Immunogen: Porcine ACTH conjugated to BSA. Available Date: 38566...
Goat polyclonal to BACE1 ( Abpromise for all tested applications). entrezGeneID: 23621 SwissProtID: P56817...
... (Ser385) Immunogen: ... acid region encompassing the human, ... Accession Number: ... Quality Assurance: Routinely evaluated ...
Mouse monoclonal [MN-8C4] to zona radiata ( Abpromise for all tested applications). Antigen: Purified eggshell proteins (zona radiata proteins and small amounts of zona pellucida proteins) from ...
Biology Products: