Navigation Links
Three-in-one virus killer prevents common, often fatal infections

A novel combination therapy drastically reduces the infection rate of three viruses ?and risk of death ?in transplant patients with compromised immune systems. The findings, to be reported in the Nov. 1 print edition of Nature Medicine, originate from a study conducted at Baylor College of Medicine, The Methodist Hospital, and Texas Children's Hospital.

The journal has posted the findings online.

The phase 1 trial, funded by the National Heart, Lung, and Blood Institute, one of the National Institutes of Health, tested the first multivirus killer of its kind, called Trivirus-specific cytotoxic T lymphocytes (CTLs), which control infections caused by three commonplace viruses ?cytomegalovirus (CMV), Epstein-Barr virus (EBV), and adenovirus. Although benign in people with normal immune systems, the viruses can cause life-threatening illnesses in transplant patients and others with compromised immune systems.

The CTLs proved effective and safe in all 11 bone marrow transplant patients, who recovered completely within two to four weeks of being treated without any side effects or toxicity. Preexisting therapies for adenovirus have had little success ?there is an 80 percent chance of death following the development of adenovirus.

"Not only were patients prevented from getting these infections after transplant, but those patients who had infections responded to the T-cell therapy and did not require any other treatment," said senior author Dr. Catherine Bollard, assistant professor of pediatrics, immunology, and medicine at BCM and a researcher at the Center for Cell and Gene Therapy at BCM, Methodist and Texas Children's. "To make dramatic recoveries like these was really quite something."

The research team drew cells from bone marrow donors and "trained" T-cells to target the three viruses before injecting them into transplant recipients.

"Drugs only control the virus. They don't cure the underlying problem," sai
'"/>

Source:Baylor College of Medicine


Page: 1 2

Related biology news :

1. Association of herpesvirus with lung disorder questioned
2. Topical treatment shown to inhibit HIV and herpes simplex virus infection
3. Elusive HIV shape change revealed; Key clue to how virus infects cells
4. Newly discovered virus linked to childhood lung disorders and Kawasaki disease
5. Live Recombinant Adenovirus Vaccine Technique Explored
6. Marburg virus disease in Angola - update
7. Studies reveal methods viruses use to sidestep immune system
8. Norovirus, AIDS vaccine and Hepatitis Virus
9. Epstein-Barr virus protein crucial to its role in blood cancers
10. Live vaccines more effective against horse herpes virus
11. Turning viruses into allies against cancer
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Three one virus killer prevents common often fatal infections

(Date:1/22/2015)... OXFORD, Conn. , Jan. 20, 2015 NXT-ID, Inc. (NASDAQ: ... growing mobile commerce market, reports on the recent success of the Wocket™ ... Wocket smart wallet was named as one of the ... of the "5 Best Products Launched At CES So Far" by Newseveryday.com ...
(Date:1/22/2015)... Research and Markets ( http://www.researchandmarkets.com/research/wxdglm/global_wearable ) ... Wearable Technologies Market and Applications, Opportunities, Industry Analysis, ... 2014-2020" report to their offering. , ... can be worn on the user,s body and ...
(Date:12/22/2014)... Conn. , Dec. 22, 2014  NXT-ID, Inc. (NASDAQ: ... biometric authentication company focused on the growing mobile commerce market, ... Apollo Robbins for the 2015 International CES debut ... Apollo Robbins will be at the NXT-ID booth January ...
Breaking Biology News(10 mins):CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 2CES Response for NXT-ID's Wocket Smart Wallet Kicks Off 2015 3Global Wearable Technologies Market and Applications, Opportunities, Industry Analysis, Segmentation, Size, Growth, Share, Overview, Trends and Forecast 2014-2020 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 2NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 3NXT-ID Hires Master Pickpocket and Security Consultant Apollo Robbins for Wocket Smart Wallet CES 2015 Debut 4
... to join the pantheon of superstars in the materials ... size, shape and physical identity, vanadium dioxide can now ... researchers with the U.S. Department of Energy (DOE),s Lawrence ... robotic torsional muscle/motor made from vanadium dioxide that for ...
... peer into a tidepool anywhere along the northeastern U.S. coast, ... They,re most likely common Atlantic slipper shells, a species of ... ubiquitous snails, and discovered that how their larvae swim is ... cranny along the coast. And to how the snails may ...
... YORK , Dec. 19, 2013 /PRNewswire-iReach/ -- HGH.us.com, a ... factual information about HGH and anti aging, has ... will include information about the latest anti aging therapies. The ... aging HGH supplements, weight loss trends, diets, and current special ...
Cached Biology News:A micro-muscular breakthrough 2A micro-muscular breakthrough 3Oh, the places you'll go -- if you're an Atlantic slipper shell 2HGH Supplements Information Website HGH.us.com Announces New Discounts on Sytropin and Genf20 Plus 2HGH Supplements Information Website HGH.us.com Announces New Discounts on Sytropin and Genf20 Plus 3
(Date:1/22/2015)... 22, 2015 Shimadzu Scientific Instruments ... multipurpose UV-visible spectrophotometer. Offering wavelength scanning from 190 ... ideal for applications in a variety of industries, ... The user-friendly UV-1280 enables intuitive operation, while the ...
(Date:1/22/2015)...  Transwestern | RBJ today announces the firm brokered a long-term ... a leading biopharmaceutical company, at Two Ledgemont Center in ... Richards , president, and Brian Cohen , senior vice ... building at 95 Hayden Ave. Photo - ...
(Date:1/22/2015)... Protocol Networks brings independent technology consulting ... brand-neutral, independent consultants, Protocol Networks has recently announced its ... the years, his company has attracted several clients in ... as well as others. With the success of these ...
(Date:1/22/2015)... 2015 zFlo Motion , a US ... an exciting product from a new partner. STT-Systems ... the past 15 years, with offerings in the optical-motion capture, ... IMU system (inertial measurement unit), iSen, is opening eyes around ...
Breaking Biology Technology:Shimadzu’s New Monitored Single-Beam UV-Vis Spectrophotometer Offers Comprehensive Measurement Options in a Compact Body 2Transwestern?RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Protocol Networks Brings Independent Technology Consulting to the Constitution State 23D Motion Capture Just Got Easy 2
... LONDON , February 4 GlaxoSmithKline ... return to,sales growth for the first time since 2007. , ... also announced,a reduction in the investment into treatments for pain and depression and ... "Now obviously I don,t like to see anybody leave the organisation ...
... Global ... ... a unique opportunity today to engage, innovate and deliver sustainable solutions to the growing global ... CEO Forum of the Delhi Sustainable Development Summit 2010 in India. , , ...
... , Research Superiority Award to Enable Recruitment of Stellar ... (TcSUH-ARH) , HOUSTON , Feb. 3 ... Award from the Texas Emerging Technology Fund (ETF), announced today by ... The University of Houston ,s Texas Center for Superconductivity (TcSUH) ...
Cached Biology Technology:Sustainability Is A Business Imperative 2UH Superconductivity Center Receives Texas Emerging Technology Fund Award 2UH Superconductivity Center Receives Texas Emerging Technology Fund Award 3UH Superconductivity Center Receives Texas Emerging Technology Fund Award 4UH Superconductivity Center Receives Texas Emerging Technology Fund Award 5UH Superconductivity Center Receives Texas Emerging Technology Fund Award 6UH Superconductivity Center Receives Texas Emerging Technology Fund Award 7
... the translation boosting Cap 1 structure. mScript™ ... 40% to 80% capped using co-transcriptional systems) ... mScript™ also features the Cap 1 structure, ... to 50% more efficient in in vivo ...
...
Request Info...
... pPIC9K and pPIC3.5K vectors carry the kanamycin ... Reagent in Pichia. Spontaneous generation of multiple ... to increased levels of Geneticin Reagent. Pichia ... screened for their level of resistance to ...
Biology Products: