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Three-dimensional, miniature endoscope opens new diagnostic possibilities

application in a live animal, the researchers used the system to image metastatic ovarian tumors on the abdominal wall of a mouse. The SEE probe was passed into the abdominal cavity through a fine-gauge needle. The resulting three-dimensional image showed several raised areas of tumor nodules, the presence of which was confirmed by histologic analysis of the tissue.

"The most important feature of this new endoscope is the ability to obtain three-dimensional images, something we don't believe is offered by any commercially available miniature endoscope system," says Dvir Yelin, PhD, first author of the Nature paper. "While the image resolution we achieved in this demonstration is similar to existing small-diameter endoscopes, with further optimization of the optics it is possible to obtain images with 10 times the number of pixels provided by other miniature endoscopes."

"This new technology will offer physicians and surgeons the capability to bring many more procedures into outpatient settings, reduce anesthesia requirements and minimize tissue damage," Tearney adds. "The device's size and flexibility should allow safer navigation through such delicate structures as the salivary ducts, the fallopian tubes and the pancreatic duct. Fetal and pediatric procedures may also benefit from this tool. Eventually, SEE could give rise to new procedures that permit diagnosis and microsurgery in previously inaccessible areas of the body."


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Source:Massachusetts General Hospital


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