Navigation Links
The structure of a virus infecting bacteria resembles a human virus

New research has revealed that the structure of a bacteriophage, a virus infecting bacteria, resembles that of certain dangerous viruses that infect people. Studying this bacteriophage reveals various characteristics about viruses and their life cycle without having to study actual human viruses.

Structural biologists Juha Huiskonen and Sarah Butcher from the Academy of Finland Virus Research Centre of Excellence, University of Helsinki, have determined the structure of the double-stranded RNA virus (phi6) in co-operation with their colleagues in the European Molecular Biology Laboratory (EMBL). The virus in question is a bacteriophage, which means that instead of eukaryotic cells it infects bacteria. To the researchers' surprise, its structure turned out to be very similar to human viruses, such as rotavirus. Rotaviruses are the most common cause of severe diarrhoea, particularly in neonatal babies and young children. Diarrhoea is one of the main causes of infant mortality in developing countries.

By studying the viruses in bacteria, researchers can determine various characteristics about the life cycle of viruses that are much harder to study using dangerous human viruses. The newly described structure of the bacteriophage furthers researchersâ?super>TM understanding of how the particles of the double-stranded RNA virus are formed in the host cell. However, it is still unclear how the virus distinguishes itsâ?super>TM own genetic information from that of other corresponding cellular molecules. Studying these events with the bacteriophage will help the understanding of similar events in human viruses.

The similarity of double-stranded RNA viruses that infect different organisms is probably due to their mutual, primitive origin. During evolution, the basic structure has been maintained even though the gene sequences of the viruses have changed dramatically. Corresponding similarities between different viruses have earlier been detected between a double-stranded DNA bacteriophage and an archaeal virus.


'"/>

Source:University of Helsinki


Related biology news :

1. Man and mouse share genome structures
2. Scientists solve structure of key protein in innate immune response
3. Vascular structure and function improve with diet and exercise
4. Biochemists report discovery of structure of major piece of telomerase; implications for cancer
5. SuperLigands - a database of ligand structures derived from the Protein Data Bank
6. PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information
7. DNA constraints control structure of attached macromolecules
8. Scripps research scientists solve structure of a critical innate immune system protein
9. Major advance made on DNA structure
10. Protein structure key for AIDS, cell function
11. Computers close in on protein structure prediction
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:7/20/2017)... Delta (NYSE: DAL ) customers now can use fingerprints instead ... National Airport (DCA). ... Delta launches biometrics to board aircraft at Reagan Washington National Airport ... Delta,s biometric boarding pass experience that launched in ... the boarding process to allow eligible Delta SkyMiles Members who are enrolled ...
(Date:5/16/2017)... May 16, 2017  Veratad Technologies, LLC ( www.veratad.com ... age and identity verification solutions, announced today they will ... 2017, May 15 thru May 17, 2017, in ... International Trade Center. Identity impacts the ... in today,s quickly evolving digital world, defining identity is ...
(Date:4/18/2017)... -- Socionext Inc., a global expert in SoC-based imaging and computing solutions, ... which features the company,s hybrid codec technology. A demonstration utilizing TeraFaces ... will be showcased during the upcoming Medtec Japan at Tokyo Big ... Las Vegas Convention Center April 24-27. ... Click here for an image of ...
Breaking Biology News(10 mins):
(Date:10/10/2017)... ... 2017 , ... For the second time in three years, ... Award. Representatives of the FirstHand program travelled to Washington, D.C. Tuesday, October 10th, ... mission is to change the trajectory of STEM education in America by dramatically ...
(Date:10/10/2017)... ... October 10, 2017 , ... The Pittcon Program ... honoring scientists who have made outstanding contributions to analytical chemistry and ... 2018, the world’s leading conference and exposition for laboratory science, which will be ...
(Date:10/9/2017)... San Antonio, Texas (PRWEB) , ... ... ... a new study published on October 5, 2017, in the medical journal, ... demonstrated equivalence with the gold standard, video EEG, in detecting generalized tonic-clonic ...
(Date:10/6/2017)... , ... October 06, 2017 , ... ... a lunch discussion and webinar on INSIGhT, the first-ever adaptive clinical trial for ... Dana-Farber Cancer Institute. The event is free and open to the public, but ...
Breaking Biology Technology: