Navigation Links
The structure of a virus infecting bacteria resembles a human virus

New research has revealed that the structure of a bacteriophage, a virus infecting bacteria, resembles that of certain dangerous viruses that infect people. Studying this bacteriophage reveals various characteristics about viruses and their life cycle without having to study actual human viruses.

Structural biologists Juha Huiskonen and Sarah Butcher from the Academy of Finland Virus Research Centre of Excellence, University of Helsinki, have determined the structure of the double-stranded RNA virus (phi6) in co-operation with their colleagues in the European Molecular Biology Laboratory (EMBL). The virus in question is a bacteriophage, which means that instead of eukaryotic cells it infects bacteria. To the researchers' surprise, its structure turned out to be very similar to human viruses, such as rotavirus. Rotaviruses are the most common cause of severe diarrhoea, particularly in neonatal babies and young children. Diarrhoea is one of the main causes of infant mortality in developing countries.

By studying the viruses in bacteria, researchers can determine various characteristics about the life cycle of viruses that are much harder to study using dangerous human viruses. The newly described structure of the bacteriophage furthers researchersâ?super>TM understanding of how the particles of the double-stranded RNA virus are formed in the host cell. However, it is still unclear how the virus distinguishes itsâ?super>TM own genetic information from that of other corresponding cellular molecules. Studying these events with the bacteriophage will help the understanding of similar events in human viruses.

The similarity of double-stranded RNA viruses that infect different organisms is probably due to their mutual, primitive origin. During evolution, the basic structure has been maintained even though the gene sequences of the viruses have changed dramatically. Corresponding similarities between different viruses have earlier been detected between a double-stranded DNA bacteriophage and an archaeal virus.


'"/>

Source:University of Helsinki


Related biology news :

1. Man and mouse share genome structures
2. Scientists solve structure of key protein in innate immune response
3. Vascular structure and function improve with diet and exercise
4. Biochemists report discovery of structure of major piece of telomerase; implications for cancer
5. SuperLigands - a database of ligand structures derived from the Protein Data Bank
6. PHACCS, an online tool for estimating the structure and diversity of uncultured viral communities using metagenomic information
7. DNA constraints control structure of attached macromolecules
8. Scripps research scientists solve structure of a critical innate immune system protein
9. Major advance made on DNA structure
10. Protein structure key for AIDS, cell function
11. Computers close in on protein structure prediction
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:5/16/2017)... , May 16, 2017   Bridge ... health organizations, and MD EMR Systems , ... development partner for GE, have established a partnership ... Portal product and the GE Centricity™ products, including ... EMR. These new integrations will ...
(Date:4/19/2017)... York , April 19, 2017 ... as its vendor landscape is marked by the presence ... market is however held by five major players - ... Together these companies accounted for nearly 61% of the ... the leading companies in the global military biometrics market ...
(Date:4/13/2017)... , April 13, 2017 UBM,s Advanced ... will feature emerging and evolving technology through ... Innovation Summits will run alongside the expo portion of ... sessions, panels and demonstrations focused on trending topics within ... advanced design and manufacturing event will take place June ...
Breaking Biology News(10 mins):
(Date:5/16/2017)... (PRWEB) , ... May 16, 2017 , ... ... and Trademark Office (USPTO) for a wireless electrocardiogram (ECG or EKG) acquisition and ... to be integrated into clothing, or secured directly onto the skin, making them ...
(Date:5/16/2017)... YORK , May 16, 2017 ... many healthcare organizations and something that has been ... record (EHR) optimization. But according to   Logicalis ... US, an international IT solutions and managed services ... – and often overlooked – interrelationship between telehealth, ...
(Date:5/16/2017)... MA (PRWEB) , ... May 16, 2017 , ... On ... have an ideal audience for introducing the advance in stem cell medicine that his ... Tuesday will be the second day of the Alliance for Regenerative Medicine’s first partnering ...
(Date:5/15/2017)... Somerset, N.J. (PRWEB) , ... May 15, 2017 ... ... advanced delivery technologies and development solutions for drugs, biologics and consumer health products, ... biotechnology company focused on rare genetic diseases, to support preclinical and clinical development ...
Breaking Biology Technology: