Navigation Links
The nude mouse tale: Omega-3 fats save the life of a terminal cancer patient

Ron Pardini is not a medical doctor. Yet he is seen as a hero by his cancer-stricken neighbor, "D.H." Pardini helped the 78-year-old after D.H. was diagnosed with terminal lung cancer.

"In 2000 he was told by his doctor he had only a few months to live," said Pardini, a professor of biochemistry and associate director of the Nevada Agricultural Experiment Station at the University of Nevada, Reno. "But five years later, he is still alive, and has even gained a little weight."

The cancerous tumors found in D.H.'s lungs have shrunk to 10 percent of what they were in 2000, according to last year's computed tomography (CT) scans.

What worked with DH is not a common medical treatment such as chemotherapy or surgical excision. It was a nutritional intervention, drastically increasing the patient's intake of omega-3 fatty acids, which are often found in fish oil or golden algae oil.

Pardini's previous research showed that omega-3 fatty acids significantly depressed the growth of human mammary, ovarian, colon, prostate and pancreatic cancer cells that were injected into athymic mice--also known as nude mice.

His studies also demonstrated that fish oil consumption improves a mouse's responsiveness to chemotherapy.

Fish oil research was inspired by observations that Inuit Eskimo populations have less breast and prostate cancer deaths. So far, though, most studies in this country are limited to animal models, but a case study about D.H., which was published in the recent issue of the Nutrition and Cancer journal, could be a major step forward for human clinical trials.

While beginning to take high dose of fish oil and golden algae oil capsules daily, D.H. also reduced corn-based foods from his diet. Corn contains omega-6 fatty acids that Pardini said are found to increase cancer growth.

Pardini is optimistic of what his findings may contribute to cancer treatment.

"We have good evidence for employing nutritional interventions to improve cancer treatment and patient well-being," he said.

Pardini wants to be able to provide viable non-toxic, over-the-counter solutions for the numerous people with fear of cancer in the back of their minds. The Nutrition and Cancer article is co-authored by Nevada nutrition Professor David Wilson and University of Nevada medical school Professors Steven Schiff, Stephen Bajo and Randall Pierce.


Source:University of Nevada College of Agriculture, Biotechnology, and Natural Resources

Related biology news :

1. Man and mouse share genome structures
2. Genome-wide mouse study yields link to human leukemia
3. Report that delayed motherhood decreases life expectancy of mouse offspring
4. Agilent Technologies introduces advanced zebrafish, mouse microarrays for stem cell and developmental biology research
5. Stem cells in bone marrow replenish mouse ovaries
6. Mosaic mouse technique offers a powerful new tool to study diseases and genetics
7. Researchers extend mouse lifespan by protecting against free radicals
8. Gene therapy advance treats hemophilia in mouse models
9. Targeting a key enzyme with gene therapy reversed course of Alzheimers disease in mouse models
10. New technique could alter field of mouse genetics
11. Building a better mouse model of lung cancer: FHIT counts
Post Your Comments:

(Date:6/20/2016)... Securus Technologies, a leading provider of ... safety, investigation, corrections and monitoring announced that after ... secured the final acceptance by all three (3) ... Systems (MAS) installed. Furthermore, Securus will have contracts ... by October, 2016. MAS distinguishes between legitimate wireless ...
(Date:6/7/2016)... June 7, 2016  Syngrafii Inc. and San ... relationship that includes integrating Syngrafii,s patented LongPen™ eSignature ... This collaboration will result in greater convenience for ... union, while maintaining existing document workflow and compliance ... ...
(Date:6/1/2016)... NEW YORK , June 1, 2016 ... Biometric Technology in Election Administration and Criminal Identification to ... According to a recently released TechSci Research report, " ... Sector, By Region, Competition Forecast and Opportunities, 2011 - ... $ 24.8 billion by 2021, on account of growing ...
Breaking Biology News(10 mins):
(Date:6/24/2016)... , June 24, 2016 Epic Sciences ... detects cancers susceptible to PARP inhibitors by targeting ... cells (CTCs). The new test has already been ... in multiple cancer types. Over 230 ... damage response pathways, including PARP, ATM, ATR, DNA-PK ...
(Date:6/23/2016)... June 23, 2016   Boston Biomedical , ... compounds designed to target cancer stemness pathways, announced ... granted Orphan Drug Designation from the U.S. Food ... gastric cancer, including gastroesophageal junction (GEJ) cancer. Napabucasin ... to inhibit cancer stemness pathways by targeting STAT3, ...
(Date:6/23/2016)... Prostate Cancer Foundation (PCF) is pleased to announce 24 new Young Investigator ... Members of the Class of 2016 were selected from a pool of 128 ... About the Class of 2016 PCF Young Investigators ... ... ...
(Date:6/23/2016)... Durham, NC (PRWEB) , ... June 23, 2016 , ... ... Odense University Hospital in Denmark detail how a patient who developed lymphedema after being ... (fat) tissue. The results could change the paradigm for dealing with this debilitating, frequent ...
Breaking Biology Technology: