Navigation Links
Test for early detection of prostate cancer shows promise

In the first clinical study of a new blood protein associated with prostate cancer, researchers have found that the marker, called EPCA or early prostate cancer antigen, can successfully detect prostate cancer in its earliest stages. At the same time, the marker successfully avoids the problem of false positive results that plagues prostate-specific antigen (PSA) testing.

Study results appear in the May 15, 2005, issue of Cancer Research. The lead author is Robert H. Getzenberg, Ph.D., professor of urology and director of research at the James Buchanan Brady Urological Institute at Johns Hopkins.

The traditional two-step approach of PSA testing and digital rectal examination has helped doctors identify prostate tumors early, while the cancers can still be cured. But PSA testing, like many disease-screening procedures, misses some cases of cancer and in other cases erroneously highlights noncancerous conditions.

“This new blood test, when coupled with PSA screening, may help reduce the number of both unnecessary biopsies and undetected prostate tumors,?said Getzenberg, In addition to being highly sensitive to prostate cancer, the EPCA test is also very specific to it, meaning that other cancers and benign prostate conditions are not detected, thus boosting doctors?confidence that a positive EPCA test is really a sign of prostate cancer, added Getzenberg.

“Once this test is refined and approved for general use, it will have an impact on the detection and treatment of prostate cancer,?said Getzenberg.

For the current study, Getzenberg and colleagues developed a simple test that would detect EPCA in the blood and then measured the EPCA levels in 46 patients, including those with prostate cancer (12 patients), bladder cancer (six patients), colon cancer (two patients), kidney cancer (one patient), spinal cord injury (seven patients) and noncancerous prostate inflammation (two patients), and 16 healthy individuals. The study was cond
'"/>

Source:Johns Hopkins


Page: 1 2

Related biology news :

1. UCSB scientists probe sea floor venting to gain understanding of early life on Earth
2. Neuronal traffic jam marks early Alzheimers disease
3. New imaging method gives early indication if brain cancer therapy is effective, U-M study shows
4. In the migratory marathon, parasitized monarchs drop out early
5. PET/CT can identify new cancer lesions at early stage, allowing for prompt treatment
6. Confocal imaging promises early detection of skin cancer
7. Measles Deaths Worldwide Drop By Nearly 40% Over Five Years
8. Oldest cranial, dental and postcranial fossils of early modern European humans confirmed
9. A whole lot of shaking goin on triggers early hatching in red-eyed tree frogs
10. New mitochondrial DNA gene chip may be early cancer diagnosis tool
11. MicroRNA tweaks protein that controls early heart development
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Test for early detection prostate cancer shows promise

(Date:5/22/2013)... cellular DNA can endanger the whole organism, as they ... Ludwig-Maximilians-Universitaet (LMU) in Munich now report how byproducts of ... , The DNA in our cells controls the form ... The instructions for this are encoded in the linear ... bases adenine (A), cytosine (C), guanine (G) and thymine ...
(Date:5/22/2013)... known as phthalates (pronounced THAL-ates) are odorless, colorless ... flooring, plastic cups, beach balls, plastic wrap, intravenous ... and Preventionthe bodies of most Americans. Once perceived ... A growing collection of evidence suggests dietary exposure ... mix with food) may cause significant metabolic and ...
(Date:5/21/2013)... in the body, stem cells in the blood ... into mature immune cells that can fight off ... these cell populations, potentially leading to the development ... a team of researchers led by biologists at ... that, in mouse models, the molecule microRNA-146a (miR-146a) ...
Breaking Biology News(10 mins):DNA damage: The dark side of respiration 2Study links chemicals widely found in plastics and processed food to elevated blood pressure in children and teens 2Keeping stem cells strong 2
... WALNUT CREEK, CA -- A powerful set of computational ... genomes flooding the public domain is now available in ... data management system hosted by the U.S. Department of ... content of IMG 2.3, upgraded with new microbial genomes ...
... the hottest fields in research, investment, and manufacturing. ... Revolution." , But how many Americans ... feel that the potential benefits of nanotechnology will ... monitor the safety of new technologies? And will ...
... popular building blocks of nanotechnology and is commonly used ... the most part, DNA is looked upon as a ... bottom up. Now a team of researchers at Young ... and lithography tools to form features such as nanochannels, ...
Cached Biology News:Upgraded IMG 2.3 Data Management System released by DOE JGI to eager user community 2Upgraded IMG 2.3 Data Management System released by DOE JGI to eager user community 3Nanotechnology: What's that? 2Unmasking DNA 2
(Date:5/23/2013)... Patheon Inc ., a leading provider ... pharmaceutical industry, will host a complimentary webinar on “Cleaning ... Tuesday, June 4, 2013 at 11 a.m. Eastern Standard ... comply with regulations for cleaning validation. Many companies ... and little evaluation of risk. Some companies have ...
(Date:5/23/2013)... May 23, 2013 PI’s new ... and provide 15 mm travel range with closed-loop ... small dimensions make these new positioners the ideal ... A vacuum rated version is also available. ... and datasheets can be found at: , ...
(Date:5/23/2013)... , May 23, 2013 BioTrends ... and advisory firms for specialized biopharmaceutical issues, finds ... and infectious disease specialists reported that in the ... (e.g., intentionally delaying treatment) in anticipation of the ... six months ago, when only 6 percent reported ...
(Date:5/23/2013)... (PRWEB) May 23, 2013 The New ... STEM industries, Black Data Processing Associates (BDPA), is hosting ... June 8, 2013. This all-day event will encourage students ... learn the ins and outs from many of the ... p.m. at the New Jersey Institute of Technology, the ...
Breaking Biology Technology:Patheon to Present on “Cleaning Validation: Science, Risk and Novel Approaches to Testing” 2Precision Positioning System Uses Miniaturezed Piezo Linear Motor: LPS-24 Linear Stage by PI 2The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 2The Majority of Physicians that Treat Hepatitis C Virus (HCV) Have Begun "Warehousing" and Preparing Their HCV Patients for the Next Generation of HCV Treatments 3Black Data Processing Associates (BDPA) New Jersey Hosts 10th Annual Families in Technology Day June 8, 2013 2
... FOLD ) will announce third quarter 2008 ... Monday, November 3, 2008. The results,announcement will be ... that,afternoon at 5 p.m. ET., Interested participants ... p.m. ET by dialing 877-419-6591 (U.S./Canada) or 719-325-4858,(international). ...
... /Xinhua-PRNewswire-FirstCall/ -- China Medical,Technologies, Inc. (the "Company") ... device company that develops, manufactures and markets ... it will report selected,unaudited financial numbers including ... for the second fiscal quarter ended September ...
... Oct. 27 Carna Biosciences, Inc. ("Carna"),announced on ... Agreement with,Shanghai Universal Biotech Company ("SUBC"). Under the ... distributor of Carna,s Protein,Kinases within China., With ... in,the life sciences, major biopharmaceutical companies have now ...
Cached Biology Technology:Amicus Therapeutics Announces Third Quarter 2008 Results Release Date 2China Medical Technologies Announces Reporting Dates for the September Quarter Results and Addresses Investor Inquiries 2China Medical Technologies Announces Reporting Dates for the September Quarter Results and Addresses Investor Inquiries 3Carna Biosciences Signs Distribution Agreement with Shanghai Universal Biotech Company 2
Black Polypropylene 384 Round Well Plate 70/Box...
... Rabbit polyclonal to Peroxiredoxin 1 ... family, whose mammalian members have been ... differentiation, and apoptosis. Many isoforms (about ... the amino acid sequence homology, particularly ...
... Eliminates nonspecific products due to inactivity ... allows extension through DNA regions which contain ... an 'A' overhang ,TEMPase II is ... Polymerase that remains inactive at room ...
... Synucleins are small, soluble proteins expressed ... tumors. The family includes three known proteins: ... The alpha and beta synuclein proteins are ... are seen mainly in presynaptic terminals. ...
Biology Products: