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Tendency to hair loss inherited from the mother

d. The gene for the androgen receptor lies on the x chromosome. Men always inherit the x chromosome from their mother. In many cases men therefore take after their grandfather on their mother's side rather than their father. However, this defect is not simply caused by one gene: "We have indications that other genes are involved which are independent of the parents' sex," Prof. Nöthen stresses. The hereditary defect can therefore sometimes also be passed on directly from father to son. Bald men wanted

In order to identify more genes involved the research team is searching for more volunteers. "Men under 40 with severe hair loss can take part," Dr. Kruse says. "If they have a brother who is affected and the parents are also prepared to give blood samples, so much the better. Volunteers taking part in the study will, of course, be paid for their assistance."

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The project is being supported by the German Research Association (DFG) and the Alfried Krupp von Bohlen und Halbach Foundation. Professor Nöthen holds the Alfried Krupp von Bohlen und Halbach Chair of Genetic Medicine. The Life & Brain Centre is a new research team at the Bonn University Clinic which uses state of the art technologies to carry out application-oriented aetiology.

The original paper can be downloaded from the following URL: http://www.journals.uchicago.edu/AJHG/journal/issues/v77n1/42360/42360.web.pdf


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Source:University of Bonn


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