Navigation Links
Tendency to hair loss inherited from the mother

It begins with receding hairlines, the forehead becomes higher, the hair at the back of the man's head gets thinner and thinner. Every second man suffers from greater or lesser hair loss. There are hardly any successful counter-measures ?despite an enormous range of obscure lotions and tinctures.

It has long been suspected that hereditary factors are important in causing hair loss. However, up to now it was unclear which genes are involved. The researchers in the team headed by Professor Markus Nöthen of the Life & Brain Centre of the Bonn University Clinic and Dr. Roland Kruse of the Skin Clinic of Düsseldorf University Clinic seem to have now discovered one of the factors responsible for the first time.

For several years the researchers had searched nationwide for families in which several men were affected by hair loss. In blood samples taken from the volunteers they then looked for candidate genes ?and eventually discovered them: in their initial step they succeeded in narrowing down the search to a series of areas on various chromosomes. In an area where the largest contribution was suspected lay the gene for the androgen receptor. "One variant of this gene was found among men who suffered from premature balding at a very early stage very much more often than among men who still had a full head of hair when over 60," Professor Nöthen says.

More androgen receptors in the scalp

Probably the genetic variant results in more androgen receptors in the scalp. "Our findings permit two explanations," Axel Hillmer from Prof. Nöthen's team explains. "Either more androgen receptors are formed among the men affected, or the variant of the receptor which develops as a result of the genetic change is more stable and is not broken down so quickly. Both mechanisms can lead to the effect of the androgens becoming greater, which in turn brings about hair loss."

The findings are also interesting for the aspect of how hair loss is inherite
'"/>

Source:University of Bonn


Page: 1 2

Related biology news :

1. Genetic therapy reverses nervous system damage in animal model of inherited human disease
2. Gene therapy cures inherited liver disease in rats
3. Cell therapy slows progression of an inherited neurological disease; Improves motor skills in mice
4. Origin of inherited pain disorder pinpointed
5. Early-stage immune system control of HIV may depend on inherited factors
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Tendency hair loss inherited from the mother

(Date:8/19/2014)... Aug. 19, 2014 To improve students, chances ... grades, the University of Houston (UH) implemented a ... students at risk for failure. , Through ... Board (THECB), the Department of Biology and Biochemistry ... students taking "General Biology" for non-majors and "Introductory ...
(Date:8/19/2014)... is available in German . ... intermittent energy sources. If a large amount of electricity is ... excess energy will have to be stored during productive periods ... storage capacities are far from adequate for the purpose. Science ... important focus lies on battery systems that used to be ...
(Date:8/19/2014)... lemur. It,s not an African Bush Baby or even a ... downright "cool" primate from Southeast Asia. , "It,s really not ... Brown, curator-in-charge at the University of Kansas, Biodiversity Institute. "A ... body; a long tail with a furry tuft at the ... a bit like the disks on the digits of tree ...
Breaking Biology News(10 mins):University of Houson program earns kudos for improving grades, retaining students 2University of Houson program earns kudos for improving grades, retaining students 3Asian inventions dominate energy storage systems 2Asian inventions dominate energy storage systems 3Philippine tarsier gets boost from Kansas research, and genetic proof of a new variety 2Philippine tarsier gets boost from Kansas research, and genetic proof of a new variety 3
... by global warming can prove extremely destructive to island habitats, ... C. Bellard, C. Leclerc and F. Courchamp of the ... possible scenarios, from optimistic to very pessimistic, to bring attention ... biodiversity hotspots worldwide. The study was published in the open ...
... measures carbon dioxide and suggests that far from being a ... a biological signalling molecule. Researchers led by Professor Nick ... of Warwick have shown that the body senses carbon dioxide ... receptor for the gas. Connexin 26 is better known as ...
... largest lake in Britain and Ireland, Lough Neagh, has lost ... to researchers at Queen,s University Belfast., The study by Quercus, ... number of diving ducks migrating to the lake for the ... in the space of a decade., The research, published in ...
Cached Biology News:Island biodiversity in danger of total submersion with climate change 2Carbon dioxide's new-found signalling role could be applied to blood flow, birth and deafness 2Largest lake in Britain and Ireland has lost three-quarters of winter water birds 2
(Date:8/18/2014)... unprecedented efficiency and data storage may someday ... electric polarizations to read and write digital ... data-driven technology. But ferroelectrics must first overcome ... curious habit of "forgetting" stored data. ... of Energy,s Brookhaven National Laboratory have discovered ...
(Date:8/18/2014)... 2014 According to a ... "Life Science Reagents Market(Products- PCR Reagent Kits, Cell ... Diagnostic Reagents and Others; End Users- Commercial and ... and Forensic Laboratories)- Global Industry Analysis, Size, Share, ... global life science reagents market was valued at ...
(Date:8/18/2014)... , Aug. 18, 2014 TNI BioTech, Inc. ... pioneering the manufacturing and marketing of innovative therapies for ... Company is providing a second notice of TNI BioTech,s ... making the announcement, Noreen Griffin , founder and ... advance for your participation in the Annual Meeting. On ...
(Date:8/18/2014)... 2014 China is increasingly being ... clinical research industry. Clinicaltrial.gov statistics highlight the popularity ... aging population; a high increase in infectious diseases; ... populated pool of patients and a track record ... points, China also presents challenges for the clinical ...
Breaking Biology Technology:Promising ferroelectric materials suffer from unexpected electric polarizations 2Promising ferroelectric materials suffer from unexpected electric polarizations 3Promising ferroelectric materials suffer from unexpected electric polarizations 4Global Life Science Reagents Market Expected to Reach USD 25.7 Billion in 2019: Transparency Market Research 2Global Life Science Reagents Market Expected to Reach USD 25.7 Billion in 2019: Transparency Market Research 3Global Life Science Reagents Market Expected to Reach USD 25.7 Billion in 2019: Transparency Market Research 4Global Life Science Reagents Market Expected to Reach USD 25.7 Billion in 2019: Transparency Market Research 5TNI BioTech Inc., provides 2nd Notice of Annual Meeting September 4, 2014 2TNI BioTech Inc., provides 2nd Notice of Annual Meeting September 4, 2014 3TNI BioTech Inc., provides 2nd Notice of Annual Meeting September 4, 2014 4China – Land of Opportunities & Challenges for the Clinical Research Industry, New Webinar Hosted by Xtalks 2
... when theoretical work is eventually supported by experimentation. Such ... Italian and US scientists when they received preliminary confirmation ... that is currently orbiting the Earth on the Foton-M3 ... week ago, the scientists are already very excited about ...
... Board Reflects Emphasis on Drug Development and Recent ... ... Lexicon,Pharmaceuticals, Inc. (Nasdaq: LXRX ) announced several changes to ... drug development and the completion of a major strategic financing,with ...
... NanoBio(R) Corporation, a,biopharmaceutical company developing novel anti-infective ... infections, today announced,the addition of four new scientists ... PharmD, Ph.D.; Susan Ciotti, Ph.D.; Robert L. Hagan, ... developing and commercializing,its novel topical anti-infectives and mucosal ...
Cached Biology Technology:Fluid theory confirmed by Foton 2Lexicon Appoints Judith Swain, M.D. to Board of Directors 2Lexicon Appoints Judith Swain, M.D. to Board of Directors 3Lexicon Appoints Judith Swain, M.D. to Board of Directors 4NanoBio Expands Drug Development Team for Its Anti-Infective Products 2NanoBio Expands Drug Development Team for Its Anti-Infective Products 3
... spotting and preparation for MS analysis. ... can be accurately and continuously spotted onto ... solutions can be added automatically. This allows ... MALDI-TOF-MS measurements. By using it in conjunction ...
A camera based compact unit for high speed scanning of 2D barcoded tubes in a cluster rack. This reader has been designed to read both 96 and 48 tube rack configurations and be compatible with common...
A compact, high-speed single tube reader unit designed for benchtop 2D barcode reading. The unit can be used with all of ABgene's 2D barcoded tubes, including the 2ml CryoCode tube....
... Enzymatic method stops PCR carry-over ... ,Designed to degrade PCR products from ... nucleic acid templates, which improves amplification ... core reagents and GeneAmp instrument systems ...
Biology Products: