Navigation Links
Technique makes it easier to see mouse embryo in all its glory

A fast, high-resolution, 3D mouse embryo visualization technique developed by collaborators at the University of Texas Health Science Center at San Antonio and the University of Utah will revolutionize the way birth defects and cancer genes are studied in animal models. That's the prediction of the researchers in an article to be published online in PLoS Genetics on April 28, a peer-reviewed, open-access journal from the Public Library of Science.

The new tool, called Virtual Histology, has already boosted the researchers' ability to study the mouse embryo and more rapidly focus on abnormalities of development, including childhood cancers. Birth defects are diagnosed in 150,000 babies in the U.S. annually. Suspected causes are genetic abnormalities, environmental insults, and drug and chemical exposures.

Charles Keller, M.D., assistant professor at the Children's Cancer Research Institute (CCRI) at The University of Texas Health Science Center at San Antonio, is studying ways to improve treatment of two types of childhood cancers '" brain tumors called medulloblastomas and muscle tumors called alveolar rhabdomyosarcomas. Dr. Keller, a pediatric oncologist, moved to the CCRI from the University of Utah in 2005, and continues his collaborations with engineers and computer scientists at Utah's Scientific Computing and Imaging Institute. Dr. Keller routinely works with mouse embryos in trying to understand the role of developmentally regulated genes in the types of cancers that children sometimes acquire. The study of genetically modified embryos and their birth defects is usually a slow and laborious process, but Dr. Keller and colleagues have found a way to make the analysis much faster '" and more accurate.

Traditional histology involves embedding embryos in wax, thinly slicing the wax and delicately placing it on slides, staining the sections and viewing slides under the microscope, then mentally reconstructing the three-dimensional aspect
'"/>

Source:Public Library of Science


Page: 1 2 3

Related biology news :

1. New Technique for Tracking Gene Regulators
2. Live Recombinant Adenovirus Vaccine Technique Explored
3. Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment
4. Researchers Find New Technique To Identify Fetal Genetic Material From Amniotic Fluid
5. Techniques available to detect soil that inhibits destructive soybean pest
6. Technique offers new view of dynamic biological landscape
7. Technique speeds up detecting, treating wound bacteria
8. Technique monitors thousands of molecules simultaneously
9. University of Manchester makes made-to-measure skin and bones a reality using inkjet printers
10. Grass makes environmentally friendly biofuel
11. Shampoo detergent added to paint makes surfaces self-sterilizing
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Technique makes easier see mouse embryo all its glory

(Date:7/24/2014)... Angeles, where electric cars ply silent freeways, solar panels ... beneath the earth, from howling winds and from the ... that it is technically and economically feasible to convert ... renewable energy. Published in Energy , the plan ... energy supply in California that could create tens of ...
(Date:7/24/2014)... 24, 2014 Some sticky research out of York ... a certain species of toxic grass fungus: moose saliva ... Biology Letters , "Ungulate saliva inhibits a grassendophyte ... to red fescue grass (which hosts a fungus called ... slower fungus growth and less toxicity. , "Plants have ...
(Date:7/24/2014)... of researchers has developed a new nanoscale agent for ... for assessing the function and properties of the GI ... and treatment of gut diseases. , Illnesses ... and inflammatory bowel disease all occur in the intestine ... with diseases such as diabetes and Parkinson,s. , ...
Breaking Biology News(10 mins):Stanford study shows how to power California with wind, water and sun 2Stanford study shows how to power California with wind, water and sun 3Stanford study shows how to power California with wind, water and sun 4Moose drool inhibits growth of toxic fungus: York U research 2New imaging agent provides better picture of the gut 2
... Inc., today announced that its 12,200 Online Books ... of HINARI, AGORA and OARE, benefitting research and ... including Malawi, Cambodia, and Bolivia. Research4Life provides ... low cost access to peer-reviewed online content from ...
... /PRNewswire-iReach/ -- Successful businesses stay connected to the ... with industry leaders at global biotech conferences with ... go to learn about new innovations, how to ... and risks while overcoming regulatory and technological hurdles. ...
... by English naturalist Charles Darwin on the Galapagos Islands, ... as isolation on a particular island, can lead to ... natural selection. Natural selection is a process whereby ... successive generations, while unfavorable heritable traits become less common. ...
Cached Biology News:Over 12,000 Wiley Online Books made available in developing countries via Research4Life 2Early Bird Conference Registrations Expiring This Friday 2Early Bird Conference Registrations Expiring This Friday 3Early Bird Conference Registrations Expiring This Friday 4LSU professor discovers how new corals species form in the ocean 2LSU professor discovers how new corals species form in the ocean 3
(Date:7/24/2014)... 2014 Gain recognition for leadership ... of the biotech industry. Nominations are now being ... to you by the Bio Supply Management ... chain management professionals for the past 7 years. ... the Biotech industry – Manufacturers, Service Providers, Material ...
(Date:7/24/2014)... , July 24, 2014  Asterias Biotherapeutics, Inc. ... emerging field of regenerative medicine, announced today that ... presentation to investors on Tuesday, July 29, 2014, ... presentation will include an overview of Asterias, business ... webcast, visit http://www.ustream.tv/channel/asterias-biotherapeutics at least 15 ...
(Date:7/24/2014)... trained personnel, and detection dogs to safeguard airports ... revolutionary new electronic chip with nano-sized chemical sensors ... , The groundbreaking nanotechnology-inspired sensor, devised by Prof. ... of Chemistry and Center for Nanoscience and Nanotechnology, ... up the scent of explosives molecules better than ...
(Date:7/24/2014)... scientists are making progress in devising suitable means ... relies on quantum dotsa kind of artificial atom, ... new study demonstrates that changing the coupling of ... impulses can help better control them. This has ... quantum information units, which would produce faster quantum ...
Breaking Biology Technology:Call for Submission: BSMA’s Supply Chain Management Innovation Awards 2Call for Submission: BSMA’s Supply Chain Management Innovation Awards 3Asterias Biotherapeutics Announces Live Investor Webcast 2Asterias Biotherapeutics Announces Live Investor Webcast 3Asterias Biotherapeutics Announces Live Investor Webcast 4Nano-sized chip 'sniffs out' explosives far better than trained dogs 2
... Remove >90% of mammalian RNA from , ... Simple procedure takes less than 2 hours , ... Seamless integration with , MICROB Express ... microarray expression analysis with , bacterial RNA isolated from host cells ...
... , , ... methods to isolate high quality RNA from a large number of ... the RNAqueous-96 , Kit . This kit, which ... of intact RNA in a 96-well plate format. An optional on-the-filter , ...
... Amplification Kits-- Now Available with Cy Dyes , ... Extremely sensitive , ArrayScript Reverse , ... yields , ... 4000-fold amplification of mRNA , Optimized buffers--high dye coupling efficiency , ...
Cached Biology Technology:Bacterial RNA Isolation From Infected Eukaryotic Hosts 2Bacterial RNA Isolation From Infected Eukaryotic Hosts 3Bacterial RNA Isolation From Infected Eukaryotic Hosts 4Bacterial RNA Isolation From Infected Eukaryotic Hosts 5Bacterial RNA Isolation From Infected Eukaryotic Hosts 6Automating RNA Isolation 2Automating RNA Isolation 3Automating RNA Isolation 4Automating RNA Isolation 5aRNA Synthesis and Labeling for Array Analysis 2aRNA Synthesis and Labeling for Array Analysis 3aRNA Synthesis and Labeling for Array Analysis 4aRNA Synthesis and Labeling for Array Analysis 5
Request Info...
See product name for description....
... Amino acid mixture excluding l-[U-14C]methionine, ... containing 2% ethanol, sterilized. > ... mCi/mg atom carbon. Mixture of ... Ile, Leu, Lys, Phe, Pro, Ser, ...
Request Info...
Biology Products: