Navigation Links
Technique makes it easier to see mouse embryo in all its glory

A fast, high-resolution, 3D mouse embryo visualization technique developed by collaborators at the University of Texas Health Science Center at San Antonio and the University of Utah will revolutionize the way birth defects and cancer genes are studied in animal models. That's the prediction of the researchers in an article to be published online in PLoS Genetics on April 28, a peer-reviewed, open-access journal from the Public Library of Science.

The new tool, called Virtual Histology, has already boosted the researchers' ability to study the mouse embryo and more rapidly focus on abnormalities of development, including childhood cancers. Birth defects are diagnosed in 150,000 babies in the U.S. annually. Suspected causes are genetic abnormalities, environmental insults, and drug and chemical exposures.

Charles Keller, M.D., assistant professor at the Children's Cancer Research Institute (CCRI) at The University of Texas Health Science Center at San Antonio, is studying ways to improve treatment of two types of childhood cancers '" brain tumors called medulloblastomas and muscle tumors called alveolar rhabdomyosarcomas. Dr. Keller, a pediatric oncologist, moved to the CCRI from the University of Utah in 2005, and continues his collaborations with engineers and computer scientists at Utah's Scientific Computing and Imaging Institute. Dr. Keller routinely works with mouse embryos in trying to understand the role of developmentally regulated genes in the types of cancers that children sometimes acquire. The study of genetically modified embryos and their birth defects is usually a slow and laborious process, but Dr. Keller and colleagues have found a way to make the analysis much faster '" and more accurate.

Traditional histology involves embedding embryos in wax, thinly slicing the wax and delicately placing it on slides, staining the sections and viewing slides under the microscope, then mentally reconstructing the three-dimensional aspect
'"/>

Source:Public Library of Science


Page: 1 2 3

Related biology news :

1. New Technique for Tracking Gene Regulators
2. Live Recombinant Adenovirus Vaccine Technique Explored
3. Technique may allow cancer patients to freeze eggs, preserving fertility before starting treatment
4. Researchers Find New Technique To Identify Fetal Genetic Material From Amniotic Fluid
5. Techniques available to detect soil that inhibits destructive soybean pest
6. Technique offers new view of dynamic biological landscape
7. Technique speeds up detecting, treating wound bacteria
8. Technique monitors thousands of molecules simultaneously
9. University of Manchester makes made-to-measure skin and bones a reality using inkjet printers
10. Grass makes environmentally friendly biofuel
11. Shampoo detergent added to paint makes surfaces self-sterilizing
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Technique makes easier see mouse embryo all its glory

(Date:5/21/2015)... 21, 2015 The Sync Project™ , ... for health, today announced a collaborative partnership with ... will center on collaboration on original research, joint course ... in the collaboration, The Sync Project and BerkleeICE are ... Medicine" in the 2015-2016 academic year.  ...
(Date:5/19/2015)... YORK , May 19, 2015  Technology is ... both internally and in the cloud. Passwords and their ... use of OTP and standards-based specifications such as those ... the outmoded use of passwords presents for BYOD, COPE, ... a unified biometric identity protocol. In ...
(Date:5/14/2015)... 2015  Verificient Technologies, Inc., a technology ... remote proctoring, announced a new alliance partnership ... creator of the Canvas Learning Management System ... will benefit from the seamless integration of ... a fully integrated multifactor biometrics behavioral application, ...
Breaking Biology News(10 mins):The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 2The Sync Project Announces Partnership with Berklee College of Music's Institute for Creative Entrepreneurship 3HYPR Corp. Biometric Security Integration Kit Shields Applications and Devices Across the Internet of Things 2HYPR Corp. Biometric Security Integration Kit Shields Applications and Devices Across the Internet of Things 3Verificient and Instructure Announce Alliance Partnership to Provide Online Proctoring for K-12 and Higher Education Institutions 2
... It is estimated that 38 million people worldwide are ... are added each year. For scientists to design treatment ... essential to learn more about how the virus mutates ... by University of Victoria biomedical engineer Stephanie Willerth has ...
... lapatinib, trastuzumab and paclitaxel significantly improved tumor response rates ... cancers, according to data presented at the 33rd Annual ... Full results were presented at the symposium during a ... CT. Reporters who cannot attend in person ...
... Today, the International Osteoporosis Foundation (IOF) and the World ... University of Sheffield, UK announced the launch of a FRAX ... freely accessible online calculator which has been developed by the ... risk of fragility fractures based on clinical risk factors, with ...
Cached Biology News:UVic biomedical engineer 'outsmarts' HIV 2Combination therapy reduced HER2-positive breast cancers 2WHO Fracture Risk Assessment Tool (FRAX) newly released for Singapore 2
(Date:6/3/2015)... Calif. , June 3, 2015 The ... life of myeloma patients while working toward prevention and ... Annual International Myeloma Working Group (IMWG) Summit June 8-10 ... 100-plus IMWG members will attend the 2015 Summit, which ... the European Hematology Association (EHA).  The focus of the ...
(Date:6/3/2015)... On April 21, 2015, California Senate Bill ... (11-0) and indicates the legislature's desire to support both individual ... Committee Chairman supports the bill and would like to see ... and would also like to see any new participants be ... List” and timing are extremely important. , To be considered ...
(Date:6/3/2015)... CHICAGO , June 3, 2015 ... CIR), a specialty biopharmaceutical company focused on allergy, today ... Company,s novel immunotherapy candidates targeting house dust mite, grass ... European Academy of Allergy and Clinical Immunology (EAACI) Annual ... on 6-10 June. Sunday, 7 June 2015 ...
(Date:6/3/2015)... Innovative biomass supply chain industry leader, ... sponsorship of the first annual Advanced Bioeconomy Feedstocks ... Hotel in New Orleans, June 9-10, the conference brings ... to further the advancements of feedstock by discussing pressing ... logistics, yield improvement and more. , As ...
Breaking Biology Technology:International Myeloma Foundation Brings Together 100 of the World's Top Myeloma Experts June 8-10 in Vienna, Austria for 6th Annual Summit 2International Myeloma Foundation Brings Together 100 of the World's Top Myeloma Experts June 8-10 in Vienna, Austria for 6th Annual Summit 3International Myeloma Foundation Brings Together 100 of the World's Top Myeloma Experts June 8-10 in Vienna, Austria for 6th Annual Summit 4Bmark Energy Announces the Sign-up Deadline for Companies Interested in California’s Direct Access Program is June 12th, 2015 at 5:00pm. 2Circassia to Present at EAACI Annual Meeting, Barcelona, Spain, 6-10 June 2015 2Circassia to Present at EAACI Annual Meeting, Barcelona, Spain, 6-10 June 2015 3Genera to Sponsor Advanced Bioeconomy Feedstocks Conference 2015 2Genera to Sponsor Advanced Bioeconomy Feedstocks Conference 2015 3
... Orleans and Biloxi by Hurricane Katrina has released another type ... making deadly weather even deadlier. The debate wont help last ... prepare us for tomorrows hurricanes. , ,About a month before ... climate researcher at the Massachusetts Institute of Technology published a ...
... - When you don't use or refrigerate your dairy products, ... stem cells may have the same problem. Except instead of ... new study in the magazine Nature Genetics ... few cell types that self-renew, show deviations in their genetic ...
... Waukesha, Wis. -- DSC Logistics has selected ... Management system to improve productivity and customer service ... DCS Logistics , with corporate offices in ... solution at all of its logistics centers. ...
Cached Biology Technology:In the wake of Katrina, more questions than answers about global climate change 2In the wake of Katrina, more questions than answers about global climate change 3New study reveals potential instability in stem cells 2New study reveals potential instability in stem cells 3
... a complete, flexible system designed specifically ... as is frequently required in biological ... Instechs miniature Clark-style polarographic electrode. Measuring ... diameter (3.2 mm), it is ideal ...
... the family of human cullin genes (CUL-1, -2, -3, ... cdc53 gene. Cullin-3 is proposed to be a part ... with cyclin E and targets it for ubiquitination, which ... an activator of cdk2, which leads the cell to ...
... The MetaVue Imaging System is the cost-effective ... With commands tailored to common research imaging ... morphometric analysis and simple image analysis. ... control library means that MetaVue has the ...
... miRCURY Array LNA microarray slides for ... microarray slides incorporate Exiqons unique Locked Nucleic ... and excellent mismatch discrimination for short microRNA ... less than 1 g total RNA (no ...
Biology Products: