Navigation Links
Taipan venom no snake oil

Australian snakes' venom could provide the next generation of human therapeutic drugs.

A blood-clotting protein in taipan venom has been identified by Queensland University of Technology PhD researcher Liam St Pierre to rapidly stop excessive bleeding during vascular surgery and major trauma.

The genetic code for the toxin, Factor X (Factor Ten), was identified by PhD researcher Liam St Pierre from QUT's School of Life Sciences who studied the venom of eight of Australia's deadliest land snakes for their therapeutic potential.

His study focussed on the genes in the coastal taipan's venom that are responsible for the pro coagulant or blood clotting agent called Factor X which could stem blood flow in a matter of seconds.

A drug lead based on Factor X is being evaluated for clinical trials by bio pharmaceutical development company QRxPharma.

"Australian snakes literally have a two-pronged attack when they bite their prey," Dr St Pierre said.

"Firstly, venom injection causes massive blood clots instantaneously followed by paralysis as a result of neurotoxins which eventually immobilise and kill the victim."

Dr St Pierre said mammals and snakes naturally produced a small amount of Factor X in their livers.

"Snakes produce a more stable and faster acting form of Factor X in their venom which is the only source of Factor X other than mammalian livers," he said.

"They have developed the ability to deliver massive fatal doses of Factor X to specifically target the systems ofmammals."

Dr St Pierre studied the venom of the inland and coastal taipan, the common brown, the red bellied black, the mulga, the rough-scaled snake, Stephens banded snake and the tiger snake.

"Only the mulga did not have Factor X as it has developed its own unique mechanism of killing."

Dr St Pierre said snake venom was a huge untapped source of potential drug therapies.

His study is the most detailed
'"/>

Source:Research Australia


Page: 1 2

Related biology news :

1. Researchers find first evidence of venom system in extinct mammal
2. Evolution mystery: Spider venom and bacteria share same toxin
3. Stanford snake venom study shows that certain cells may eliminate poison
4. Radioactive scorpion venom for fighting cancer
5. Tarantula venom and chili peppers target same pain sensor
6. Nonvenomous Asian snakes borrow defensive poison from toxic toads
7. Venom doc tracks down snake bioweapons
8. Researchers reveal secrets of flying snakes
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Taipan venom snake oil

(Date:8/19/2014)... the seas during warm phases and became extinct during ... establishes a link between marine crocodilian diversity and the ... than 140 million years. , The research, led ... France and formerly from the University of Bristol, UK ... Today, crocodiles are ,cold-blooded, animals that mainly live in ...
(Date:8/19/2014)... ever had a glass of fizzy soda knows that ... in a finding with wide industrial applications, Princeton researchers ... down into the liquid as well. , "It is ... we were surprised, and fascinated, to discover that when ... injected tiny oil droplets into the water," said Howard ...
(Date:8/19/2014)... Rochelle, August 19, 2014A new ovoid structure discovered in ... clay, contains a variety of minerals, and shows evidence ... resulting melting of the permafrost and mixing of surface ... broad range of analytical studies to determine the origin ... for how this ovoid formed, point to the most ...
Breaking Biology News(10 mins):Evolution of marine crocodilians constrained by ocean temperatures 2Bubbling down: Discovery suggests surprising uses for common bubbles 2Bubbling down: Discovery suggests surprising uses for common bubbles 3Life on Mars? Implications of a newly discovered mineral-rich structure 2
... Doha, Qatar Urgent law enforcement action by governments ... crucial to addressing the illicit ivory trade, according to ... Detailed regional summaries of the data held in ... database on ivory seizures, highlight the failure of law ...
... ever before of how much radiation reaches sensitive tissues ... models of the human body being developed at the ... of computer simulation tools and 3-D patient models that ... said Wesley E. Bolch, Ph.D., a professor in the ...
... monster movies, but palaeontologists have discovered evidence of how an ... place 4 million years ago. Such fossil evidence ... of bite marks on an otherwise well-preserved dolphin skeleton, the ... that led to the death of the dolphin, and determined ...
Cached Biology News:New analysis points to ivory enforcement failures in parts of Africa, Asia 2Age, gender can affect risk to radiation treatment 2Age, gender can affect risk to radiation treatment 3Jaws -- 4 million BC 2
(Date:8/18/2014)... Global HIV Infection Drug Market and ... Reportstack. The rate of HIV infection and the number of ... at a positive rate across the globe. It has been ... 2005 to 1.5 in 2013, with the rates for children ... changes in the infection rates has been the improved access ...
(Date:8/18/2014)... China is increasingly being recognized ... research industry. Clinicaltrial.gov statistics highlight the popularity of ... population; a high increase in infectious diseases; a ... pool of patients and a track record of ... China also presents challenges for the clinical research ...
(Date:8/16/2014)... Madison, Virginia (PRWEB) August 16, 2014 ... of NDA Partners LLC announced today that Agnes ... Premier Expert consultant. NDA Partners Premier Experts are ... enable them to bring extraordinary value to the ... implement critical solutions to help clients successfully develop ...
(Date:8/15/2014)... DUBLIN , Aug. 15, 2014 Research ... "Global non-GMO Food Market 2014-2018" report to their offering. ... stands for genetically modified organism, in this the scientist conducts ... genes from the DNA of an organism, such as a ... of the plant they want to alter or make genetic ...
Breaking Biology Technology:Global HIV Infection Drug Market Overview 2Global HIV Infection Drug Market Overview 3Global HIV Infection Drug Market Overview 4China – Land of Opportunities & Challenges for the Clinical Research Industry, New Webinar Hosted by Xtalks 2Former GlaxoSmithKline Senior Executive Agnes Westelinck Joins NDA Partners as a Premier Expert Consultant 2Global non-GMO Food Market 2014-2018: Key Vendors are Amy's Kitchen, Nature's Path, Organic Valley and The Hain Celestial 2Global non-GMO Food Market 2014-2018: Key Vendors are Amy's Kitchen, Nature's Path, Organic Valley and The Hain Celestial 3
... 2011 Inovio Pharmaceuticals, Inc. (NYSE Amex: ... and preventive vaccines against cancers and infectious diseases, announced ... showed remarkable immune responses in monkeys, following similarly strong, ... data from earlier animal studies. The data was presented ...
... the term "splitsville" usually means "check your prenup." ... from boron nitride nanotubes, "splitsville" could mean "happily ... National Laboratory (Berkeley Lab) and the University of ... University, have developed a technique in which boron ...
... HAYWARD, Calif., June 28, 2011 Intarcia Therapeutics, ... results of a phase 2 clinical study of ... for the treatment of type 2 diabetes at ... San Diego, California. (Logo:   http://photos.prnewswire.com/prnh/20050301/SFTU126LOGO ...
Cached Biology Technology:Inovio Pharmaceuticals' Prostate Cancer DNA Vaccine Demonstrates Strong T Cell Responses in Monkeys; Company on Track for Phase I Clinical Trial 2Inovio Pharmaceuticals' Prostate Cancer DNA Vaccine Demonstrates Strong T Cell Responses in Monkeys; Company on Track for Phase I Clinical Trial 3Inovio Pharmaceuticals' Prostate Cancer DNA Vaccine Demonstrates Strong T Cell Responses in Monkeys; Company on Track for Phase I Clinical Trial 4Inovio Pharmaceuticals' Prostate Cancer DNA Vaccine Demonstrates Strong T Cell Responses in Monkeys; Company on Track for Phase I Clinical Trial 5Inovio Pharmaceuticals' Prostate Cancer DNA Vaccine Demonstrates Strong T Cell Responses in Monkeys; Company on Track for Phase I Clinical Trial 6Splitsville for boron nitride nanotubes 2Splitsville for boron nitride nanotubes 3Splitsville for boron nitride nanotubes 4Intarcia Presents Positive Phase 2 48-week Results From ITCA 650 Study at the American Diabetes Association 71st Scientific Sessions 2Intarcia Presents Positive Phase 2 48-week Results From ITCA 650 Study at the American Diabetes Association 71st Scientific Sessions 3Intarcia Presents Positive Phase 2 48-week Results From ITCA 650 Study at the American Diabetes Association 71st Scientific Sessions 4Intarcia Presents Positive Phase 2 48-week Results From ITCA 650 Study at the American Diabetes Association 71st Scientific Sessions 5
SpectroQuest single beam 4nm UV/Vis spectrophotometer; stand-alone unit; large angled LCD screen; large sample compartment...
Fluorescence Preserving Media, 100 mL...
... Blunt-Ended PCR Cloning Kit, 40 reactions. ... cloning of all PCR products with ... cloning approaches by offering consistently better ... 25-fold more positive clones.Amplicons generated by ...
... development to targets including proteins and to ... cancer-specific surface antigens. A&Gs service is ... in approximately 40 days (duration may vary ... Phase I: Immunization, test bleed and ...
Biology Products: