Navigation Links
Taipan venom no snake oil

Australian snakes' venom could provide the next generation of human therapeutic drugs.

A blood-clotting protein in taipan venom has been identified by Queensland University of Technology PhD researcher Liam St Pierre to rapidly stop excessive bleeding during vascular surgery and major trauma.

The genetic code for the toxin, Factor X (Factor Ten), was identified by PhD researcher Liam St Pierre from QUT's School of Life Sciences who studied the venom of eight of Australia's deadliest land snakes for their therapeutic potential.

His study focussed on the genes in the coastal taipan's venom that are responsible for the pro coagulant or blood clotting agent called Factor X which could stem blood flow in a matter of seconds.

A drug lead based on Factor X is being evaluated for clinical trials by bio pharmaceutical development company QRxPharma.

"Australian snakes literally have a two-pronged attack when they bite their prey," Dr St Pierre said.

"Firstly, venom injection causes massive blood clots instantaneously followed by paralysis as a result of neurotoxins which eventually immobilise and kill the victim."

Dr St Pierre said mammals and snakes naturally produced a small amount of Factor X in their livers.

"Snakes produce a more stable and faster acting form of Factor X in their venom which is the only source of Factor X other than mammalian livers," he said.

"They have developed the ability to deliver massive fatal doses of Factor X to specifically target the systems ofmammals."

Dr St Pierre studied the venom of the inland and coastal taipan, the common brown, the red bellied black, the mulga, the rough-scaled snake, Stephens banded snake and the tiger snake.

"Only the mulga did not have Factor X as it has developed its own unique mechanism of killing."

Dr St Pierre said snake venom was a huge untapped source of potential drug therapies.

His study is the most detailed ever conducted on the genes responsible for Australian snakes' toxins. It is hoped a comprehensive study of all the venom components from Australian snakes may yield further novel components thatcould be targeted as human drugs.


'"/>

Source:Research Australia


Related biology news :

1. Researchers find first evidence of venom system in extinct mammal
2. Evolution mystery: Spider venom and bacteria share same toxin
3. Stanford snake venom study shows that certain cells may eliminate poison
4. Radioactive scorpion venom for fighting cancer
5. Tarantula venom and chili peppers target same pain sensor
6. Nonvenomous Asian snakes borrow defensive poison from toxic toads
7. Venom doc tracks down snake bioweapons
8. Researchers reveal secrets of flying snakes
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:2/11/2016)...  According to new research from Acuity Market ... 200 fingerprint, iris, and eye-vein biometric smartphones have ... names. This includes market leaders Apple, Samsung, Huawei, ... that 600 million biometric smartphones are currently in ... Maxine Most , Acuity Market Intelligence ...
(Date:2/11/2016)... , Feb. 11, 2016  Vigilant Solutions announces today that ... are being used by Lee,s Summit ... recent location and arrest of a homicide suspect. ... covers around 65 square miles and is home to ... Department has a single mobile license plate reader system and ...
(Date:2/10/2016)... PUNE, India , February 10, 2016 ... --> According to 2016 iris ... fingerprint identification iris recognition is more widely ... are available with both fingerprint and iris ... allows the user to avoid purchasing two ...
Breaking Biology News(10 mins):
(Date:2/12/2016)... Biocom, the association representing the Southern California ... San Diego companies to Washington D.C. ... Fly-In. Biocom Fly-In participants had the opportunity to meet with ... for Medicare and Medicaid Services (CMS), the National Institutes of ... Susan Davis and Scott Peters to discuss ...
(Date:2/12/2016)... ... February 12, 2016 , ... ... Congress Center in Atlanta, Georgia, will include 848 exhibitors (count as of February ... be displaying products and services used by the scientific community in industrial, academic, ...
(Date:2/12/2016)...  BD (Becton, Dickinson and Company) (NYSE: BDX ... the launch of the BD CLiC™ System during the ... --> --> ... cost effective NGS library preparation with limited operator intervention. ... next generation sequencing (NGS) library prep instrument, engineered for ...
(Date:2/12/2016)... 12, 2016  PTC Therapeutics, Inc. (NASDAQ: ... (Strategies to Realize Innovation, Vision and Empowerment) grant ... provides funds to patient advocacy organizations to develop ... contributions to the rare disease community by increasing ... patient advocates. Mary Frances Harmon ...
Breaking Biology Technology: