Navigation Links
TGen awarded $7.1 million to accelerate brain disease research

The Translational Genomics Research Institute (TGen) today announced the receipt of a $7.1 million grant from the National Institutes of Health (NIH) to continue a project designed to uncover the genetic causes of neurological and mental health disorders using sophisticated genetic scanning technologies. This award is part of a greater $25 million grant that TGen will share with three other microarray centers that are part of the NIH Neuroscience Microarray Consortium supported by the NIH Neuroscience Blueprint (http://neuroscienceblueprint.nih.gov).

The Microarray Consortium was initially funded in 2002 by the National Institute of Neurological Disorders and Stroke (NINDS; www.ninds.nih.gov) and the National Institute of Mental Health (NIMH; www.nimh.nih.gov). The new award is supported by these two institutes as well as the thirteen other NIH Neuroscience Blueprint institutes. The consortium combines technology resources from TGen, Duke University in Durham, NC, and the University of California in Los Angeles. Because of the consortium's success and an expanding need for consortium services in neuroscience, a fourth research center, Yale University in New Haven, Connecticut, will be added to the program in June.

About 10,000 investigators from the 15 different NIH institutes that are part of the NIH Neuroscience Blueprint will have access to the technology and expertise within the consortium. These investigators will be able to further their research through the use of microarray technology used for scanning through the entire human genome (3 billion letters) and all of the genes for which it encodes (30,000-40,000 genes).

"The application of the newest and most sophisticated genome scanning technologies will allow us to unlock the mysteries of how the brain functions normally, as well as what causes common human disorders like Alzheimer's disease, multiple sclerosis, and others," said Dr. Dietrich A. Stephan, Director of the Neurogenomics D ivision at the Translational Genomics Research Institute.

Genomic scanning technologies make use of the human genome sequence to visualize how gene flavors or aberrant amounts of genes can cause human disease. The consortium centers specialize in technologies which provide information about the genes turned on or off in the diseased tissues being studied. Scientists use these microarray technologies to compare genetic patterns between an individual with a disease and an unaffected person. Using this information, investigators can identify the root causes responsible for certain disorders so that diagnostics and treatments can be developed that have a direct impact on the disease mechanisms.

The Microarray Consortium initially received $9 million from the NIH from June 2002 to June 2005, and the new funding will be approximately $25 million over the next five years.

"It is exciting to have the microarray consortium expanded in capacity and expertise to serve the entire community of neuroscientists funded by NIH institutes. The application of genomic technologies in neuroscience is an important step in the development of future therapies for diseases and disorders of the nervous system," said Dr. Thomas Miller, Program Director of Extramural Research Programs at the NINDS.

The consortium worked with 5 AM solutions, a software development company in Phoenix, to create a central database for data generated by the consortium. These data are freely available so the entire scientific community can benefit from this publicly funded endeavor.

The Neuroscience Blueprint institutes are components of the National Institutes of Health in Bethesda, Maryland and are the nation's primary supporters of basic and applied biomedical research on the brain and nervous system. Additional information about the NIH Neuroscience Microarray Consortium can be accessed at http://arrayconsortium.tgen.org.


'"/>

Source:The Translational Genomics Research Institute


Related biology news :

1. A comprehensive response to HIV could prevent 10 million AIDS deaths in Africa by 2020
2. UCLA launches $20 million stem cell institute to investigate HIV, cancer and neurological disorders
3. Six million Africans face famine because of locusts, drought
4. Retrovirus struck ancestors of chimpanzees and gorillas millions of years ago, but did not affect ancestral humans
5. Evidence of 600-million-year old fungi-algae symbiosis discovered in marine fossils
6. $5.1 billion would save 6 million children
7. Health costs soar as 60 million Americans classed as obese
8. Malaria killing a million a year
9. Spider blood found in 20 million year old fossil
10. MSU researchers receive $4 million grant to uncover gene functions
11. South Africa still debating how to tackle HIV/AIDS when 5 million are infected
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/9/2016)... Paris Police Prefecture ... solution to ensure the safety of people and operations in ... major tournament Teleste, an international technology group specialised ... today that its video security solution will be utilised by ... public safety across the country. The system roll-out is scheduled ...
(Date:6/2/2016)... , June 2, 2016   The Weather Company , ... Watson Ads, an industry-first capability in which consumers will be ... able to ask questions via voice or text and receive ... Marketers have long sought an advertising ... that can be personal, relevant and valuable; and can scale ...
(Date:5/20/2016)... 2016  VoiceIt is excited to announce its ... By working together, VoiceIt and VoicePass will ... VoicePass take slightly different approaches to voice biometrics, ... and usability. ... partnership. "This marketing and technology partnership ...
Breaking Biology News(10 mins):
(Date:6/22/2016)... 22, 2016 Cell Applications, Inc. and ... to produce up to one billion human induced ... one week. These high-quality, consistent stem cells enable ... and spend more time doing meaningful, relevant research. ... high-volume manufacturing process that produces affordable, reliable HiPSC ...
(Date:6/22/2016)... ANGELES , June 22, 2016   StockNewsNow.com ... SNNLive Video Interview with Dr. Nader Pourhassan , ... biotechnology company focused on the clinical development and potential ... prevention of HIV infection, according to the company,s website ... recorded on Tuesday, June 7 th , 2016, at ...
(Date:6/22/2016)... ... June 21, 2016 , ... New light-based technologies that facilitate ... tissue — promise to enable both compact, wearable devices for point-of-care diagnostics as well ... the skin. , Recent work and visionary future directions are detailed in a new ...
(Date:6/22/2016)... and ALBANY, N.Y. ... Corporation (Teewinot) and Albany Molecular Research, Inc. (NASDAQ: ... has licensed Teewinot,s technology to produce and sell ... standard. The CBCA analytical standard is manufactured using ... the expression of cannabinoid biosynthetic genes in microorganisms ...
Breaking Biology Technology: