Navigation Links
Swimming 'to the left' gets bacteria upstream, and may promote infection

Yale engineers who study both flow hydrodynamics and how bacteria propel themselves report that one reason for the high incidence of infections associated with catheters in hospital patients may be that some pathogenic bacteria swim "to the left," in a study published in Physical Review Letters.

"Escherichia coli (E. coli) and some other pathogenic bacteria with flagella interact with the flow of liquid when they are near a surface," said Hür Köser, assistant professor of electrical engineering at Yale and the study's senior author, who has collaborated with a diverse team of scientists for this study.

"Each cell normally has two to six flagella that can rotate together as a bundle and act as a propeller to drive the cell forward. Away from any boundaries, the cells swim in a straight line, but near a surface, opposing forces of flow and bacterial forward motion cause the bacteria to continuously swim to one side ?to the left." The study determined that swimming "to the left" is a hydrodynamic process that is fundamentally related to the way the cells propel themselves in this manner.

Köser and his colleagues show that this phenomenon allows flagellated bacteria, such as E. coli, to find crevices or imperfections on the surface, get trapped, and swim upstream. This allows the bacteria to eventually locate large reservoirs with richer sources of food and better conditions for multiplying.

"We think that upstream swimming of bacteria may be relevant to the transport of E. coli in the urinary tract," said Köser. "It might also explain the high rates of infection in catheterized patients and the incidence of microbial contamination at protected wellheads. To our knowledge, this is the first time that a natural propensity to swim upstream has been discovered and described in bacteri a."

To study the hydrodynamics of these bacteria in a flow environment, Köser's team constructed microfluidic devices using soft lithography. Inside the devices they set up various flow patterns to observe the bacteria in channels that were only 150 or 300 microns wide and between 50 and 450 microns deep. They were able to observe how the bacteria moved at a wide range of flow rates ?between 0.05 and 20 microliters per minute.


'"/>

Source:Yale University


Related biology news :

1. Swimming with dolphins can alleviate depression
2. Anti-bacterial additive widespread in U.S. waterways
3. A bacterial genome reveals new targets to combat infectious disease
4. Discovery of key proteins shape could lead to improved bacterial pneumonia vaccine
5. Scientists discover that host cell lipids facilitate bacterial movement
6. Family trees of ancient bacteria reveal evolutionary moves
7. Drug-resistant bacteria on poultry products differ by brand
8. Programmable cells: Engineer turns bacteria into living computers
9. NASA links nanobacteria to kidney stones and other diseases
10. Substance protects resilient staph bacteria
11. Physiological effects of reduced gravity on bacteria
Post Your Comments:
*Name:
*Comment:
*Email:


(Date:6/22/2016)... ANGELES , June 22, 2016 /PRNewswire/ ... identity management and verification solutions, has partnered ... edge software solutions for Visitor Management, Self-Service ... provides products that add functional enhancements ... partnership provides corporations and venues with an ...
(Date:6/21/2016)... 21, 2016 NuData Security announced today that ... of principal product architect and that Jon ... customer development. Both will report directly to ... moves reflect NuData,s strategic growth in its product ... customer demand and customer focus values. ...
(Date:6/16/2016)... SAN FRANCISCO , June 16, 2016 /PRNewswire/ ... Market size is expected to reach USD ... report by Grand View Research, Inc. Technological proliferation ... and banking applications are expected to drive the ... ) , The development of ...
Breaking Biology News(10 mins):
(Date:12/9/2016)... MA (PRWEB) , ... December 09, 2016 , ... Aditya ... that in addition to Australia, Europe, and the United States, Axiomed is now gaining ... assure interest in this technology." , Mr. Humad went on to say that, “We ...
(Date:12/9/2016)... India , December 9, 2016 According ... & Services (Primer, Probe, Custom, Predesigned, Reagent Equipment), Application (Research, PCR, ... Forecasts to 2021" published by MarketsandMarkets, the global market is expected ... in 2016, at a CAGR of 10.6% during the forecast period. ... ...
(Date:12/8/2016)... ... December 08, 2016 , ... From wearable ... is taking over sports. On Thursday, December 15th a panel of entrepreneurs, innovators ... the playing field at a Smart Talk session. Smart Talk will run from ...
(Date:12/8/2016)... and CARDIFF, UK (PRWEB) , ... December 08, ... ... very high precision light to control cells — optogenetics — is key to ... current state of the art, spatially patterned light projected via free-space optics stimulates ...
Breaking Biology Technology: