Navigation Links
SuperLigands - a database of ligand structures derived from the Protein Data Bank

Scientists have isolated the first human embryonic stem cell lines specifically tailored to match the nuclear DNA of patients, both males and females of various ages, suffering from disease or spinal cord injury.

The research is being released by the journal Science, which is published by AAAS, the non-profit science society, on the Science Express website on 19 May, 2005.

These cell lines will enable the study of human disease in cells in the laboratory. The work also moves scientists one step closer to the goal of transplanting healthy cells into humans to replace cells damaged by diseases such as Parkinson's and diabetes.

Each of the 11 new human embryonic stem cell lines was created by transferring the nuclear genetic material from a non-reproductive cell of a patient into a donated egg, or "oocyte," whose nucleus had been removed. This method is called "somatic cell nuclear transfer" or SCNT. Next, oocytes with the patient's genetic material were allowed to grow to the blastocyst stage, an early stage of embryo development. Stem cells were then derived from the inner cell mass of the blastocyst. In laboratory culture, these cell lines displayed signs of immunological compatibility with the patients' cells, Science authors reported.

Oocyte donors and patients who donated non-reproductive cells were all unpaid volunteers. All donors signed informed-consent agreements. For underage donors of non-reproductive cells, both parents signed informed-consent agreements.

Before patient-specific stem cells can potentially be used in the clinic, a variety of issues must be addressed, the researchers emphasized. The stem cell lines produced from patients with disease will likely display characteristics of the disease, so they will probably not be appropriate for direct use in treating patients. In addition, researchers must develop methods to efficiently direct the differentiation of embryonic stem cells to specific stable cell types. S
'"/>

Source:


Page: 1 2 3 4

Related biology news :

1. New comparative toxicogenomics database
2. Roche clinical trial registry and results database launched
3. wFleaBase: the Daphnia genome database
4. The shape of things to come: Morphology database going global
5. Virginia Bioinformatics Institutes launches microbial database
6. Man and mouse share genome structures
7. DNA self-assembly used to mass-produce patterned nanostructures
8. Scientists map one of biologys critical light-sensing structures
9. Sandia work launched on space shuttle shows live cells influence growth of nanostructures
10. New understanding of parasite cell structures may provide treatments for serious tropical diseases
11. Chemotherapy temporarily affects the structures of the human brain
Post Your Comments:
(Date:7/10/2014)... from The University of Texas Health Science Center at ... (IYG), a health education program designed to delay sexual ... dating violence behaviors among minority youth. , According to ... of high school youth are victims of physical dating ... percent are victims of emotional dating violence. Previous studies ...
(Date:7/10/2014)... children and teens living with a cardiac pacemaker, a ... quality of life, reports a study in the July ... , the official journal of the Society for ... published by Lippincott Williams & Wilkins , a ... may function as a protective factor against lower health-related ...
(Date:7/10/2014)... National Cancer Research Centre (CNIO) Macromolecular Crystallography Group ... protein called BuD to DNA in order to ... the researcher who led the study, says the ... the instructions contained in the genome to treat ... study is published in the journal Acta ...
Breaking Biology News(10 mins):It's Your Game ... Keep It Real reduces dating violence among minority youth 2For children with pacemakers, 'self-competence' affects quality of life 2CNIO scientists develop technology to redirect proteins towards specific areas of the genome 2
... Munich have developed a new method for visualizing material ... team led by Bert Nickel has, for the first ... organic thin-film solar cells using laser light for localized ... the scientific journal " Advanced Materials ". "We have ...
... has published research this week in a leading science ... they were raised rather than that likely to maximize ... of habitat selection theory. The paper is published ... on June 26 and includes co-authors Michael Palmer, ...
... significantly challenged as production levels fall due to ... the industry,s competitiveness are being sought. The South ... Resources and Energy (DMITRE) has invited VTT Technical ... study that identifies potential routes by which the ...
Cached Biology News:Organic electronics: Imaging defects in solar cells 2Bioeconomy as a solution for South Australia's declining forest industry 2Bioeconomy as a solution for South Australia's declining forest industry 3
(Date:1/14/2014)... , Jan. 14, 2014  3D Communications, a leading provider of ... regulatory, business, and media events in the United States ... former associate Virginia Cox , JD, is returning to the ... Virginia Cox re-joins 3D after more than two years of ...
(Date:1/14/2014)... and BETHESDA, Md. , Jan. 14, ... with two institutes from the National Institutes of Health ... bringing safer, more effective treatments to patients on a ... for Advancing Translational Sciences (NCATS) and the National Eye ...
(Date:1/14/2014)... (PRWEB) January 14, 2014 Global ... developing innovative information technology solutions for patients, physicians, ... care stakeholders, announced today the signing of a ... Food and Drug Administration (FDA). This initiative ...
(Date:1/14/2014)... 14, 2014 During the 1600’s through the ... “The Doctor’s Plague.” In this time period, doctors did not ... at times, to the death of vulnerable patients. In the ... that they may be unwittingly transmitting herpes viruses to their ...
Breaking Biology Technology:Former FDA Associate Commissioner Returns To 3D Communications 2Organovo Announces Collaboration with National Institutes of Health 2Organovo Announces Collaboration with National Institutes of Health 3Global Record Systems Announces Research Collaboration Agreement with FDA to Create a Novel “Big Data” Paradigm for Collection of Patient Safety and Outcomes Information 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 2Study: Fatigued Medical Interns Infect Their Patients with Herpes Viruses; The CBCD Sees a Parallel with “The Doctor’s Plague” 3
... Encorium Group, Inc. (Nasdaq:  ENCO), (the "Company"), ... conducting studies in over 30 countries for many ... today announced that, on October 20, 2010, it ... (the "Panel") has determined to delist the Company,s ...
... Inc (OTC: OMCM.OB) today announced that it ranked number ... 500 of the fastest growing technology, media, telecommunications, life ... are based on the percentage of fiscal year revenue ... percent during this period. OmniComm,s CEO, Cornelis ...
... even harder in recent years the influenza A virus has ... Reporting their findings in the journal Science, researchers ... not, and how future treatments can defeat the nasty bug no ... are no longer recommended by the CDC for use against flu. ...
Cached Biology Technology:Encorium Announces NASDAQ Panel Decision to Delist Common Stock; Announces Changes to its Board of Directors 2Encorium Announces NASDAQ Panel Decision to Delist Common Stock; Announces Changes to its Board of Directors 3Encorium Announces NASDAQ Panel Decision to Delist Common Stock; Announces Changes to its Board of Directors 4OmniComm Ranks Number 220 on Deloitte's 2010 Technology Fast 500 for Fastest Growing Companies in North America 2OmniComm Ranks Number 220 on Deloitte's 2010 Technology Fast 500 for Fastest Growing Companies in North America 3Putting a bull's-eye on the flu: Detailing influenza's structure for drug targeting 2
...
... The Varian 500-MS LC Ion Trap ... high-throughput LC/MS analysis where sensitivity, reliability ... 500-MS provides a robust platform for ... mass resolution, and mass stability reflect ...
... modular benchtop fume hood ventilates ... safe indoor release of exhaust. ... organic contaminants. Configurations are available ... options include final HEPA filter, ...
... ideal modular cleanroom for biological safety ... require cleanliness (to Class 10/ISO 3) ... to create ultra-smooth surfaces that are ... One-inch radius corners simplify cleaning. Unique ...
Biology Products: