Navigation Links
Successful transplantation from pig embryos to mice

Millions of diabetics face a lifetime of daily injections to replace the insulin their bodies fail to produce, as well as a host of risks that includes blindness, amputation, kidney failure, and heart disease. For many, particularly those afflicted with juvenile diabetes, transplants of the pancreatic tissue in which insulin is produced might alleviate these problems. Unfortunately, there are not nearly enough organ donors available for transplantation.

Insulin-producing pancreas tissues from animals could potentially provide a nearly unlimited supply for transplantation. But until now, attempts to transplant such animal tissues into non-human primates have evoked a fierce immune response. However, embryonic tissues, such as those from pigs (in which the insulin-producing cells are similar to those of humans), might not be rejected as strongly. New research by Prof. Yair Reisner of the Weizmann Institute's Immunology Department has brought the possibility of transplants from pig embryos one step closer. The results of the study appeared in the June issue of PLoS Medicine.

In previous work, Reisner and his team had shown that each embryonic organ has its own 'time window' during which the chances for successful transplantation are optimal. Prior to this window, the early tissue's cells, which are still largely undifferentiated, can give rise to tumors. Past the window, however, they may be too well-developed: The host identifies these cells as foreign, causing the body to reject them. By transplanting tissues from pig embryos into mice lacking proper immune systems, they determined that the best time frame for pancreatic tissue was about a third of the way through gestation (from 42 to 56 days).

In the new study, Reisner's team wanted to see if such tissues could function in the body. They first implanted embryonic pancreatic tissue from pigs into mice that lacked an immune system of their own, but had human immune cells injected into them. Fr
'"/>

Source:American Committee for the Weizmann Institute of Science


Page: 1 2

Related biology news :

1. Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics
2. Visceral Leishmaniasis: Successful Vaccine Trial In Dogs
3. Penn Surgeons Use Completely Robotic Surgery to Successfully Treat Prostate Cancer
4. Successful cell engineering may lead to mad cow prevention, say researchers
5. Successful lung cancer surgery not enough to break nicotine dependence in many smokers
6. Monkeying around to improve organ transplantation
7. New cell transplantation technique restores insulin production in diabetics
8. Diabetes researchers pioneer islet cell xenotransplantation in primate studies
9. Guiding principles for facial transplantation unveiled
10. Plastic surgeons countdown first full facial transplantation
11. Researchers create genetically matched embryonic stem cells for transplantation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Successful transplantation from pig embryos mice

(Date:3/24/2015)... March 24, 2015   NexID Biometrics LLC, ... security-authentication needs, today announced the beginning of shipments of ... The company, based in Potsdam, ... three-day Connect:ID Expo, which began here today at the ... version 2.0 of its SDK boosts the accuracy rate ...
(Date:3/23/2015)... -- SoundView Technology Group issues a new research update following ... smart wallet. SoundView was one of the selected user groups to ... Wocket in multiple scenarios and outlets. Soundview ... making both debit and credit card payments.  ... company meets their plans in 2015, it would push our ...
(Date:3/23/2015)... -- In the 2014 fiscal year, irs.gov recorded over $100 ... accounts for a fraction of the estimated losses for ... $11 billion globally. The polygraph has traditionally been used ... Investor Mark Saint Juste along with former ... partnered to administer the test in a new way: ...
Breaking Biology News(10 mins):NexID Begins Shipments Of Version 2.0 Fake-Finger-Detection Solution 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 2Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 3Technology Research Note Update from SoundView; Real-World Usage and Feedback of Wocket Smart Wallet at CVS, Whole Foods and other Retailers 4Polygraph Test Now Used to Protect Investors From Fraud 2Polygraph Test Now Used to Protect Investors From Fraud 3
... robotics technology make it possible to create prosthetics that ... capability promises to dramatically improve the mobility of lower-limb ... uneven ground, significantly reducing their risk of falling as ... bodies. That is the view of Michael Goldfarb, ...
... conditions such as current directions and water temperature play ... migrating salmon as they move from rivers and hit ... research. The findings inform restoration policies and practices focused ... The findings, from ecologists at the Department of ...
... often think about it, fluid dynamics touches almost every aspect ... flag, to swirling river currents that shape canyons to the ... of bodily functions -- urination -- is governed primarily by ... at the American Physical Society (APS) Division of Fluid Dynamics ...
Cached Biology News:Robotic advances promise artificial legs that emulate healthy limbs 2Robotic advances promise artificial legs that emulate healthy limbs 3Robotic advances promise artificial legs that emulate healthy limbs 4Tracking young salmon's first moves in the ocean 2Tracking young salmon's first moves in the ocean 3Tracking young salmon's first moves in the ocean 4The Tao of pee 2
(Date:4/27/2015)... 27, 2015 SynGen Inc., a company that ... that harvest stem and progenitor cells from umbilical cord ... today that it has added three new members to ... Blood Business Units focus on product commercialization. ... its Vice President and Chief Financial Officer.  Chuck was ...
(Date:4/27/2015)... tru Shrimp™ Systems announced today that it has ... the exclusive worldwide rights to commercialize Tidal Basin™ technology, ... agreement for the patented technology, developed by world-renowned shrimp ... China, Taiwan, France, Germany, Italy, Spain, the Netherlands and ... from all over the world for our Tidal Basin™ ...
(Date:4/24/2015)... April 24, 2015 Top student social ... San Diego area universities, including UCSD and SDSU, will ... from prominent local, national and nonprofit companies for an ... 5th Annual Social Innovation Challenge 2015 . , ... social venture ideas addressing a diverse range of issues ...
(Date:4/24/2015)... DIEGO , April 24, 2015  Pfenex Inc. ... the development of biosimilar therapeutics including high value and ... its follow-on public offering of 6,000,000 shares of its ... $15.50 per share. Of the shares being offered, 2,610,000 ... shares are being offered by existing stockholders. Pfenex will ...
Breaking Biology Technology:SynGen Inc. Expands Its Management Team 2tru Shrimp™ Systems Acquires Global Patent for Tidal Basin™ Shrimp Production 25th Annual Social Innovation Challenge at University of San Diego - Students Pitch to Live Judging Panel to Take Home $75K 25th Annual Social Innovation Challenge at University of San Diego - Students Pitch to Live Judging Panel to Take Home $75K 3Pfenex Inc. Announces Pricing Of Follow-on Offering 2
... hearings on affordable Internet access for all Chicagoans by Mayor ... ,Hopefully, what the council will get out of the testimony ... network infrastructure is as basic to supporting the city's growth ... today. , ,Some view this council as a "make ...
... Gov. Jim Doyle today proposed a joint public-private ... the development of renewable energy programs in Wisconsin. , ... low-interest loans, and grants that would come from business ... - would leverage an additional $370 million in private ...
... Eau Claire, Wis. - Two companies, including an ... Own Business" contest sponsored by the Eau Claire ... micro business and emerging-growth categories, respectively, were STAGE5, LLC, ... software, and KingBuilt.com, Inc ., a producer of ...
Cached Biology Technology:Chicago's Wi-Fi inertia harms business 2Chicago's Wi-Fi inertia harms business 3Chicago's Wi-Fi inertia harms business 4Doyle announces $80M renewable energy strategy 2Doyle announces $80M renewable energy strategy 3Doyle announces $80M renewable energy strategy 4Eau Claire business contest honors tech start ups 2
... Captivate magnetic separator for ... used in conjunction with the ... C-21476) or other magnetic particles ... 96-well microplates. Cell Biology Cell ...
ANTI DEOXY CORTICO...
RABBIT ANTI RAT AQUAPORIN 5...
...
Biology Products: