Navigation Links
Successful transplantation from pig embryos to mice

Millions of diabetics face a lifetime of daily injections to replace the insulin their bodies fail to produce, as well as a host of risks that includes blindness, amputation, kidney failure, and heart disease. For many, particularly those afflicted with juvenile diabetes, transplants of the pancreatic tissue in which insulin is produced might alleviate these problems. Unfortunately, there are not nearly enough organ donors available for transplantation.

Insulin-producing pancreas tissues from animals could potentially provide a nearly unlimited supply for transplantation. But until now, attempts to transplant such animal tissues into non-human primates have evoked a fierce immune response. However, embryonic tissues, such as those from pigs (in which the insulin-producing cells are similar to those of humans), might not be rejected as strongly. New research by Prof. Yair Reisner of the Weizmann Institute's Immunology Department has brought the possibility of transplants from pig embryos one step closer. The results of the study appeared in the June issue of PLoS Medicine.

In previous work, Reisner and his team had shown that each embryonic organ has its own 'time window' during which the chances for successful transplantation are optimal. Prior to this window, the early tissue's cells, which are still largely undifferentiated, can give rise to tumors. Past the window, however, they may be too well-developed: The host identifies these cells as foreign, causing the body to reject them. By transplanting tissues from pig embryos into mice lacking proper immune systems, they determined that the best time frame for pancreatic tissue was about a third of the way through gestation (from 42 to 56 days).

In the new study, Reisner's team wanted to see if such tissues could function in the body. They first implanted embryonic pancreatic tissue from pigs into mice that lacked an immune system of their own, but had human immune cells injected into them. Fr
'"/>

Source:American Committee for the Weizmann Institute of Science


Page: 1 2

Related biology news :

1. Successful Test Of Single Molecule Switch Opens The Door To Biomolecular Electronics
2. Visceral Leishmaniasis: Successful Vaccine Trial In Dogs
3. Penn Surgeons Use Completely Robotic Surgery to Successfully Treat Prostate Cancer
4. Successful cell engineering may lead to mad cow prevention, say researchers
5. Successful lung cancer surgery not enough to break nicotine dependence in many smokers
6. Monkeying around to improve organ transplantation
7. New cell transplantation technique restores insulin production in diabetics
8. Diabetes researchers pioneer islet cell xenotransplantation in primate studies
9. Guiding principles for facial transplantation unveiled
10. Plastic surgeons countdown first full facial transplantation
11. Researchers create genetically matched embryonic stem cells for transplantation
Post Your Comments:
*Name:
*Comment:
*Email:
TAG: Successful transplantation from pig embryos mice

(Date:1/22/2015)... 2015 Technology Showcase, Hall E -   EyeLock Inc. ... announced it will showcase its EyeLock ID technology integrated in ... of Energy,s Oak Ridge National Laboratory (ORNL) at ... iris identity authentication technology is being used to validate the ...
(Date:1/22/2015)... POINT ROBERTS, Washington , January 20, 2015 ... sectors including technology and tech stocks, releases video from the ... pickpocket and security consultant Apollo Robbins . ... about the Wocket™ biometric smart wallet, a product of NXT-ID, ...
(Date:1/22/2015)...   EyeLock, Inc. , a market leader of iris-based identity ... to the new role of Senior Vice President of ... of mobile platforms and wearable solutions for EyeLock,s technologies. Gerber ... the semiconductor industry to his role at EyeLock, with expertise ...
Breaking Biology News(10 mins):EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 2EyeLock Debuts First Iris Authentication Technology Embedded in 3D Printed Automobile 3Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 2Apollo Robbins Talks about the Illusion of Personal Safety and How Easily Your Wallet is Stolen; If a Wocket Wallet is Stolen the Thief Can't do Anything With it! 3EyeLock Names Steve Gerber as Senior Vice President of Mobile and Wearables 2
... the tiny holes in our teeth that make them ... of adults and children worldwide. , Preliminary research ... 2005 shows that creating tiny spheres of a ceramic ... or cure for sensitive teeth. , Sensitive teeth or ...
... diseases they can carry and spread to humans is ... Mike Kanost, university distinguished professor of biochemistry and head ... lab are studying how insects protect themselves against infection. ... proteins. , The researchers have made progress in understanding ...
... A sensitive new genetic test can now detect a crippling ... south to Virginia and north to Canada. Although it does ... as red tide, the disease can have a significant impact ... shellfish harvests and commercial aquaculture operations. , QPX - for ...
Cached Biology News:'Nanospheres' that block pain of sensitive teeth 2K-State researchers study insects' immune system 2New genetic test can detect clam disease 2
(Date:1/23/2015)... Portal Solutions , a technology consulting firm that ... 365 and SharePoint platforms , today announces its inclusion in ... of the region’s fastest-growing mid-sized companies based on a combined ... be recognized a second year in a row by SmartCEO ...
(Date:1/22/2015)...  Transwestern | RBJ today announces the firm brokered a long-term ... a leading biopharmaceutical company, at Two Ledgemont Center in ... Richards , president, and Brian Cohen , senior vice ... building at 95 Hayden Ave. Photo - ...
(Date:1/22/2015)... (PRWEB) January 21, 2015 Cambridge Semantics, the ... technology, today announced that 2014 was a record-breaking year across ... capabilities of the Anzo Smart Data Platform and our Smart ... utilize insights from diverse data which led to record growth ...
(Date:1/22/2015)... OH (PRWEB) January 22, 2015 Crystal Diagnostics ... today that it has received AOAC-PTM Certifications for the six ... O121, and O145; collectively referred to as STEC or the ... 1 colony forming unit (cfu) per 325 g of raw ...
Breaking Biology Technology:Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 2Washington SmartCEO Announces Portal Solutions as 2015 Future 50 Award Winner Second Year in a Row 3Transwestern | RBJ Advises Shire in 202,000 SF Lease, Creating Boston's Largest Suburban Biotech Campus 2Cambridge Semantics Announces Record Results for 2014 2Crystal Diagnostics Awarded AOAC-PTM Accreditation for the Rapid Detection of “Big 6” E.coli Food Pathogens 2
... PICK: Pinpoint accuracy: DNA vaccines that home in on ... pursued to develop new vaccines against infectious diseases is ... a DNA vaccine, the body converts the information in ... immune response. However, current DNA vaccines induce relatively weak ...
... Inc.,(TSX:SDI) today announced that Mr. Anthony Bihl has ... "As the former CEO of Siemens Medical Solutions ... Diagnostic Products,Corporation, Mr. Bihl will be a valuable ... and CEO of Spectral Diagnostics. "Mr. Bihl is ...
... IRVINE, Calif., March 6 Alsius Corporation,(Nasdaq: ALUS ... announced it will release its fourth quarter and,year-end 2007 ... A conference call and webcast to review the ... Time (4:30 p.m. Eastern Time). This call will,be open ...
Cached Biology Technology:JCI online early table of contents: March 6, 2008 2JCI online early table of contents: March 6, 2008 3JCI online early table of contents: March 6, 2008 4Spectral appoints Anthony Bihl to Board of Directors 2Alsius Corporation to Host Fourth Quarter and Year-End 2007 Financial Results Conference Call/Webcast on March 13, 2008 2
S. O'Hare & C.K. Atterwill • In vitro toxicity techniques for regular lab use. Ex vivo techniques are also covered with the aim of reducing and refining the use of animals in the future....
Form: Concentrated Applications: ELISA...
RABBIT ANTI HALOPERIDOL...
Form: Ready to use Applications: Western Blot, ELISA...
Biology Products: