( available in the waters off of her Cape...)Study identifies predictors of HIV drug resistance in patients beginning triple therapy

available in the waters off of her Cape Cod lab. The species is famous among scientists as a model for the study of cellular processes that are common among all animals, including humans. Reinisch and her colleagues collected surf clam eggs and sperm, fertilized them in vitro, and added BCE to normally developing clam embryos. The investigators used a combination of antibodies and dyes to show the presence of neurotransmitters in single neurons. "We've actually taken superlative three-dimensional pictures where we go right through the embryo," says Reinisch. The sequence of images yields a three-dimensional representation of the embryos' developing neurons. Reinisch and company examined periodically recorded images to see what effect, if any, the chemicals had. They also measured the levels of proteins in the normal and treated embryos to check the visual data. Read the full paper
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