Navigation Links
Study identifies gene in mice that may control risk-taking behavior in humans

One teenager likes to snowboard off a cliff. Another prefers to read a book and wouldn't think of trading places. Why these differences exist is a mystery, but for the first time researchers have identified a possible genetic explanation behind risk-seeking behavior.

Scientists at Fred Hutchinson Cancer Research Center have found that a specific neurodevelopmental gene, called neuroD2, is related to the development of an almond-shaped area of the brain called the amygdala, the brain's emotional seat. This gene also controls emotional-memory formation and development of the fear response, according to research led by James Olson, M.D., Ph.D., associate member of the Clinical Research Division at the Hutchinson Center.

The findings will be published in the early online edition of the Proceedings of the National Academy of Sciences the week of Sept. 26.Olson and colleagues studied mice with a single copy of the neuroD2 gene and found they had an impaired ability to form emotional memories and conditioned fear.

"Most of us are familiar with the fact that we can remember things better if those memories are formed at a time when there is a strong emotional impact - times when we are frightened, angry or falling in love," he said. "That's called emotional-memory formation. The amygdala is the part of the brain that is responsible for formation of emotional memory."

In the brain's early development, the neuroD2 gene encodes the neuroD2 protein to transform undifferentiated stem cell-like cells into neurons, or brain cells. Under the microscope, certain areas of the amygdala were absent in mice with no neuroD2 gene. In mice with just one copy of neuroD2, researchers also found fewer nerve cells in the amygdala.

Researchers conducted experiments on mice with a single copy of the neuroD2 gene to test the theory that only having one copy of the gene impacts emotional learning and the development of traits such as fear and aggressio
'"/>

Source:Fred Hutchinson Cancer Research Center


Page: 1 2 3

Related biology news :

1. Novel Asthma Study Shows Multiple Genetic Input Required; Single-gene Solution Shot Down
2. Emory Study Tests Bone Marrow Stem Cells to Improve Circulation in Legs
3. UCLA Study Shows One-Third of Drug Ads in Medical Journals Do Not Contain References Supporting Medical Claims
4. Study Demonstrates Gene Expression Microarrays are Comparable and Reproducible
5. Study Links Ebola Outbreaks To Animal Carcasses
6. Breakthrough Microarray-based Technology for the Study of Cancer
7. NYU Study Reveals How Brains Immune System Fights Viral Encephalitis
8. Study finds more than one-third of human genome regulated by RNA
9. Leukemia Drug Breakthrough Study In New England Journal Of Medicine
10. Study identifies predictors of HIV drug resistance in patients beginning triple therapy
11. New Study from Affymetrix Laboratories Points to Changing View of How Genome Works
Post Your Comments:
(Date:7/31/2014)... LA Dr. Oren Tessler, Assistant Professor of Clinical ... of Medicine, is part of a team of plastic ... using a method to screen and select patients for ... of the patients who underwent this surgery to decompress ... got a bonus cosmetic eyelid surgery. The study, which ...
(Date:7/31/2014)... NXT-ID, Inc., (NXTD: OTCQB) a biometric authentication company ... and consumers wanting to learn more about its  ... on-air today, July 31 st . ... featured in a segment of NewsWatch, a weekly ... the History Channel, FYI Network today. ...
(Date:7/30/2014)... by the Red Queen in Lewis Carroll,s Through ... Illinois and National University of Singapore improved a ... evolve over decades to millions of years. , ... for competition, incorporates the "Red Queen Effect," an ... the 1970s, which suggests that organisms must constantly ...
Breaking Biology News(10 mins):Surgeons report significant migraine relief from cosmetic eyelid surgery technique 2NXT-ID's Next Generation Biometric Smart Wallet Featured on NewsWatch Consumer Show on the History Channel and FYI Network Today, July 31st 2NXT-ID's Next Generation Biometric Smart Wallet Featured on NewsWatch Consumer Show on the History Channel and FYI Network Today, July 31st 3Classic Lewis Carroll character inspires new ecological model 2Classic Lewis Carroll character inspires new ecological model 3
... since scientists first discovered the gene that causes cystic ... causes disease remain unanswered. Using a newly created ... of cystic fibrosis, University of Iowa researchers have now ... pigs and does not end up in the correct ...
... observe behavior in fossil specimens that are dead even ... modern, living, species that has some similarities to the ancient ... University of Cincinnati professor of geology and colleagues as they ... they resemble clams or other shelled mollusks, brachiopods are more ...
... edition of the journal Fungal Biology Reviews , published ... a total of 76 videos which together comprise the most ... movies were produced by Professor Gero Steinberg of the University ... field of fungal cell biology. The editors of ...
Cached Biology News:Pig model of cystic fibrosis improves understanding of disease 2Pig model of cystic fibrosis improves understanding of disease 3Paleontologists audition modern examples of ancient behavior 2
(Date:7/31/2014)... Francisco, Calif. (PRWEB) July 31, 2014 ... newly diagnosed patients with an overview of the disease ... management of drug side effects, as well as updates ... “We’re grateful to Dr. Sandy Srinivas for organizing this ... survivor of kidney cancer. “Sandy and her colleagues have ...
(Date:7/31/2014)... July 31, 2014 Although RNA-Sequencing ... the first transcriptome-wide analyses appearing around 2008, RNA-Sequencing ... for RNA measurement. In the last several years, ... specific, work with smaller input amounts, process degraded ... blood samples). On the bioinformatics side, there have ...
(Date:7/31/2014)... MA (PRWEB) July 31, 2014 ... (UC) and collaboration company, is proud to announce ... (LMS). LMS complements Adobe Connect’s elearning tools to ... LMS delivers content with training tools for desktop ... eLearning with LMS is the perfect online training ...
(Date:7/31/2014)... July 31, 2014 Sales Horizons, a ... its online sales training course – Mastering the ... sales performance. , Drawn from proven sales training programs ... Mastering the Complex Sale online sales training course is ... who has face-to-face contact with customers, like technical support, ...
Breaking Biology Technology:The Evolution of RNA-Sequencing, Upcoming Live Webinar August 22 hosted by Xtalks 2SoundConnect Enhances Portfolio with Adobe Connect Learning Management System (LMS) 2Sales Horizons Offers Mastering the Complex Sale - a Comprehensive, Online Sales Skills Training Course 2Sales Horizons Offers Mastering the Complex Sale - a Comprehensive, Online Sales Skills Training Course 3
... 0 clinical testing has been gaining acceptance and ... development process in the years to come. The ... and technology dependence is also expected to result ... in this sector.(Logo: http://www.newscom.com/cgi-bin/prnh/20081117/FSLOGO )"There is every ...
... Health Care Business Conference, an MBA-student organized event, will be held ... distinguished speakers and panelists from Healthcare Services, Investment, Pharma, Biotech, and ... ... 10, 2009 -- The 2009 Wharton Health Care Business Conference ...
... Feb. 10 DSM Biologics and Crucell N.V. (Euronext, ... today that they have entered into an agreement with ... Vendor Network. Under the terms of the agreement, Bioceros ... licensees of the PER.C6(R) cell line located in the ...
Cached Biology Technology:Frost & Sullivan Sees Microdosing as Compelling Advantage for Big Pharma 2Frost & Sullivan Sees Microdosing as Compelling Advantage for Big Pharma 314th Annual Wharton Health Care Business Conference to Feature CEOs from WebMD, McKesson, Humana and Given Imaging 2DSM and Crucell Sign Agreement with Bioceros to Serve as Pre-Approved Cell Line Generation Partner of PER.C6(R) Cell Line Proteins 2DSM and Crucell Sign Agreement with Bioceros to Serve as Pre-Approved Cell Line Generation Partner of PER.C6(R) Cell Line Proteins 3DSM and Crucell Sign Agreement with Bioceros to Serve as Pre-Approved Cell Line Generation Partner of PER.C6(R) Cell Line Proteins 4DSM and Crucell Sign Agreement with Bioceros to Serve as Pre-Approved Cell Line Generation Partner of PER.C6(R) Cell Line Proteins 5
... Experion software, PC, is used to ... data obtained from the Experion automated ... in electropherogram and simulated gel views ... calculations in a Results table. This ...
... PRKAR2 cAMP is a signaling molecule ... cAMP exerts its effects by activating the ... signal through phosphorylation of different target proteins. ... tetramer composed of two regulatory and two ...
The large Dodeca stainer shaking rack holds the staining trays in the large Dodeca stainer....
...
Biology Products: